MX369847B - Derivados de ácido carboxilico con un anillo oxazolo [5,4-d] pirimidina. - Google Patents

Derivados de ácido carboxilico con un anillo oxazolo [5,4-d] pirimidina.

Info

Publication number
MX369847B
MX369847B MX2014000033A MX2014000033A MX369847B MX 369847 B MX369847 B MX 369847B MX 2014000033 A MX2014000033 A MX 2014000033A MX 2014000033 A MX2014000033 A MX 2014000033A MX 369847 B MX369847 B MX 369847B
Authority
MX
Mexico
Prior art keywords
carboxylic acid
acid derivatives
oxazolo
pyridine ring
formula
Prior art date
Application number
MX2014000033A
Other languages
English (en)
Other versions
MX2014000033A (es
Inventor
Schäfer Matthias
Kadereit Dieter
Huebschle Thomas
Hiss Katrin
Hachtel Stephanie
Haag-Diergarten Silke
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2014000033A publication Critical patent/MX2014000033A/es
Publication of MX369847B publication Critical patent/MX369847B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a derivados de ácido cicloalquiloxicarboxílico de la fórmula I (ver Fórmula) en donde A, R1, R2, R2b, R2C, R3 y X están definidos como se indica en las reivindicaciones. Los compuestos de la fórmula I son apropiados, por ejemplo, para la cicatrización de heridas.
MX2014000033A 2011-07-07 2012-07-06 Derivados de ácido carboxilico con un anillo oxazolo [5,4-d] pirimidina. MX369847B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11305879 2011-07-07
EP12305527 2012-05-11
PCT/EP2012/063302 WO2013004828A1 (de) 2011-07-07 2012-07-06 Carbonsäurederivate mit einem oxazolo [4, 5-c] pyridinring

Publications (2)

Publication Number Publication Date
MX2014000033A MX2014000033A (es) 2014-02-17
MX369847B true MX369847B (es) 2019-11-25

Family

ID=46514336

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000033A MX369847B (es) 2011-07-07 2012-07-06 Derivados de ácido carboxilico con un anillo oxazolo [5,4-d] pirimidina.

Country Status (17)

Country Link
US (1) US8735402B2 (es)
EP (1) EP2729475B8 (es)
JP (1) JP5913586B2 (es)
KR (1) KR20140061386A (es)
CN (1) CN103797015B (es)
AU (1) AU2012280208B2 (es)
BR (1) BR112014000078A2 (es)
CA (1) CA2841229C (es)
DK (1) DK2729475T3 (es)
ES (1) ES2547110T3 (es)
HK (1) HK1192237A1 (es)
IL (1) IL230313A (es)
MX (1) MX369847B (es)
MY (1) MY165099A (es)
PT (1) PT2729475E (es)
RU (1) RU2609003C2 (es)
WO (1) WO2013004828A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
US7060697B2 (en) * 2003-05-19 2006-06-13 Irm Llc Immunosuppressant compounds and compositions
US8530483B2 (en) * 2008-05-30 2013-09-10 Merck Sharp & Dohme Corp. Substituted azabenzoxazoles
TW201000099A (en) * 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
NZ590377A (en) 2008-07-15 2011-11-25 Sanofi Aventis Oxazolopyrimidines as edg-1 receptor agonists
US8907093B2 (en) * 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring

Also Published As

Publication number Publication date
CA2841229A1 (en) 2013-01-10
US8735402B2 (en) 2014-05-27
US20130023545A1 (en) 2013-01-24
EP2729475A1 (de) 2014-05-14
JP2014518249A (ja) 2014-07-28
CA2841229C (en) 2019-07-30
WO2013004828A1 (de) 2013-01-10
RU2014104233A (ru) 2015-08-20
IL230313A (en) 2016-08-31
ES2547110T3 (es) 2015-10-01
AU2012280208A1 (en) 2014-02-06
CN103797015A (zh) 2014-05-14
DK2729475T3 (en) 2015-09-21
AU2012280208B2 (en) 2016-07-21
MX2014000033A (es) 2014-02-17
KR20140061386A (ko) 2014-05-21
EP2729475B1 (de) 2015-06-10
BR112014000078A2 (pt) 2016-10-18
EP2729475B8 (de) 2015-08-26
RU2609003C2 (ru) 2017-01-30
MY165099A (en) 2018-02-28
HK1192237A1 (en) 2014-08-15
CN103797015B (zh) 2015-12-09
PT2729475E (pt) 2015-10-14
JP5913586B2 (ja) 2016-04-27

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