MX367364B - Formulaciones de lorazepam de liberación sostenida. - Google Patents

Formulaciones de lorazepam de liberación sostenida.

Info

Publication number
MX367364B
MX367364B MX2015008756A MX2015008756A MX367364B MX 367364 B MX367364 B MX 367364B MX 2015008756 A MX2015008756 A MX 2015008756A MX 2015008756 A MX2015008756 A MX 2015008756A MX 367364 B MX367364 B MX 367364B
Authority
MX
Mexico
Prior art keywords
lorazepam
sustained release
beads
release formulations
composition
Prior art date
Application number
MX2015008756A
Other languages
English (en)
Spanish (es)
Other versions
MX2015008756A (es
Inventor
Vachon Michael
A Saltel Douglas
Original Assignee
Edgemont Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50064764&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX367364(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Edgemont Pharmaceuticals Llc filed Critical Edgemont Pharmaceuticals Llc
Publication of MX2015008756A publication Critical patent/MX2015008756A/es
Publication of MX367364B publication Critical patent/MX367364B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5036Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MX2015008756A 2013-01-09 2014-01-09 Formulaciones de lorazepam de liberación sostenida. MX367364B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750797P 2013-01-09 2013-01-09
US201361762833P 2013-02-08 2013-02-08
PCT/US2014/010854 WO2014110245A1 (en) 2013-01-09 2014-01-09 Sustained release formulations of lorazepam

Publications (2)

Publication Number Publication Date
MX2015008756A MX2015008756A (es) 2016-03-31
MX367364B true MX367364B (es) 2019-08-16

Family

ID=50064764

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015008756A MX367364B (es) 2013-01-09 2014-01-09 Formulaciones de lorazepam de liberación sostenida.

Country Status (30)

Country Link
US (3) US8999393B1 (enExample)
EP (1) EP2943185B1 (enExample)
JP (2) JP6039823B2 (enExample)
KR (1) KR102318274B1 (enExample)
CN (1) CN105209018B (enExample)
AU (1) AU2014205440B2 (enExample)
BR (1) BR112015016304A8 (enExample)
CA (1) CA2897302C (enExample)
CL (1) CL2015001920A1 (enExample)
CY (1) CY1123933T1 (enExample)
DK (1) DK2943185T3 (enExample)
ES (1) ES2856181T3 (enExample)
HR (1) HRP20210236T1 (enExample)
HU (1) HUE054005T2 (enExample)
IL (1) IL239777B (enExample)
LT (1) LT2943185T (enExample)
MX (1) MX367364B (enExample)
NZ (1) NZ710860A (enExample)
PE (1) PE20151432A1 (enExample)
PH (1) PH12015501534B1 (enExample)
PL (1) PL2943185T3 (enExample)
PT (1) PT2943185T (enExample)
RS (1) RS61857B1 (enExample)
RU (1) RU2678324C2 (enExample)
SG (1) SG11201505349RA (enExample)
SI (1) SI2943185T1 (enExample)
SM (1) SMT202100091T1 (enExample)
UA (1) UA117233C2 (enExample)
WO (1) WO2014110245A1 (enExample)
ZA (1) ZA201505082B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019039836A2 (ko) * 2017-08-22 2019-02-28 아주대학교산학협력단 퇴행성 신경질환 치료용 복합 제형 조성물
RU2020117757A (ru) * 2017-11-01 2021-11-29 Эджмонт Фармасьютикалс, Ллк Траст Оральные фармацевтические композиции лоразепама, устойчивые к спирту

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Also Published As

Publication number Publication date
PT2943185T (pt) 2021-02-18
PL2943185T3 (pl) 2022-01-17
AU2014205440A1 (en) 2015-08-27
IL239777A0 (en) 2015-08-31
JP2017019880A (ja) 2017-01-26
UA117233C2 (uk) 2018-07-10
CA2897302C (en) 2022-05-31
PE20151432A1 (es) 2015-09-23
US20150174078A1 (en) 2015-06-25
MX2015008756A (es) 2016-03-31
SMT202100091T1 (it) 2021-03-15
AU2014205440B2 (en) 2018-07-05
JP2016504390A (ja) 2016-02-12
PH12015501534A1 (en) 2015-10-05
BR112015016304A2 (pt) 2017-07-11
CA2897302A1 (en) 2014-07-17
KR102318274B1 (ko) 2021-10-26
NZ710860A (en) 2020-05-29
EP2943185B1 (en) 2020-11-18
HRP20210236T1 (hr) 2021-03-19
CN105209018B (zh) 2019-06-25
ES2856181T3 (es) 2021-09-27
SI2943185T1 (sl) 2021-04-30
US20160228378A1 (en) 2016-08-11
RU2678324C2 (ru) 2019-01-28
RU2015128915A (ru) 2017-02-10
JP6039823B2 (ja) 2016-12-07
US8999393B1 (en) 2015-04-07
RS61857B1 (sr) 2021-06-30
HUE054005T2 (hu) 2021-08-30
EP2943185A1 (en) 2015-11-18
IL239777B (en) 2019-03-31
CN105209018A (zh) 2015-12-30
ZA201505082B (en) 2021-04-28
BR112015016304A8 (pt) 2018-01-23
CL2015001920A1 (es) 2016-01-29
KR20150118119A (ko) 2015-10-21
WO2014110245A1 (en) 2014-07-17
LT2943185T (lt) 2021-03-10
US20150110874A1 (en) 2015-04-23
PH12015501534B1 (en) 2015-10-05
SG11201505349RA (en) 2015-08-28
CY1123933T1 (el) 2022-05-27
DK2943185T3 (da) 2021-02-15
HK1213770A1 (zh) 2016-07-15

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