MX365934B - Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina. - Google Patents

Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina.

Info

Publication number
MX365934B
MX365934B MX2014000022A MX2014000022A MX365934B MX 365934 B MX365934 B MX 365934B MX 2014000022 A MX2014000022 A MX 2014000022A MX 2014000022 A MX2014000022 A MX 2014000022A MX 365934 B MX365934 B MX 365934B
Authority
MX
Mexico
Prior art keywords
oxazolo
carboxylic acid
acid derivatives
pyridine ring
compounds
Prior art date
Application number
MX2014000022A
Other languages
English (en)
Other versions
MX2014000022A (es
Inventor
Schäfer Matthias
Kadereit Dieter
Hachtel Stephanie
Huebschle Thomas
Hiss Katrin
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of MX2014000022A publication Critical patent/MX2014000022A/es
Publication of MX365934B publication Critical patent/MX365934B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula I: (ver Fórmula) en donde A, X, Y, R1, R2, R3 tienen los significados ya indicados. Los compuestos de fórmula I son adecuados por ejemplo para cicatrización de heridas.
MX2014000022A 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina. MX365934B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11305878 2011-07-07
EP12305526 2012-05-11
PCT/EP2012/063298 WO2013004827A1 (de) 2011-07-07 2012-07-06 Carbonsäurederivate mit einem Oxazolo[5,4-d]Pyrimidinring

Publications (2)

Publication Number Publication Date
MX2014000022A MX2014000022A (es) 2014-02-19
MX365934B true MX365934B (es) 2019-06-20

Family

ID=46458547

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000022A MX365934B (es) 2011-07-07 2012-07-06 Derivados de acidos carboxilicos con un anillo de oxazolo[5,4-d]pirimidina.

Country Status (17)

Country Link
US (1) US9321787B2 (es)
EP (1) EP2729471B1 (es)
JP (1) JP5913585B2 (es)
KR (1) KR20140061385A (es)
CN (1) CN103781792B (es)
AU (1) AU2012280207B2 (es)
BR (1) BR112014000118A2 (es)
CA (1) CA2841226C (es)
DK (1) DK2729471T3 (es)
ES (1) ES2544620T3 (es)
HK (1) HK1192240A1 (es)
IL (1) IL230258A (es)
MX (1) MX365934B (es)
MY (1) MY164134A (es)
PT (1) PT2729471E (es)
RU (1) RU2609008C2 (es)
WO (1) WO2013004827A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
CN103992279B (zh) * 2014-06-06 2016-06-01 重庆华邦胜凯制药有限公司 一种制备硫代巴比妥酸化合物的方法
JP6661885B2 (ja) * 2015-03-09 2020-03-11 セイコーエプソン株式会社 画像表示装置

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3679682A (en) * 1970-04-23 1972-07-25 Fmc Corp CERTAIN 5H-ISOXAZOLO{8 5,4-d{9 PYRIMIDIN-4-ONES
AU6419899A (en) * 1998-10-09 2000-05-01 Regents Of The University Of Michigan, The Hydrogels and water soluble polymeric carriers for drug delivery
AU6679400A (en) * 1999-08-27 2001-03-26 Department Of National Defence Hydrogel wound dressing containing liposome-encapsulated therapeutic agent
DE102005018389A1 (de) * 2005-04-20 2006-10-26 Sanofi-Aventis Deutschland Gmbh Azolderivate als Inhibitoren von Lipasen und Phospholipasen
WO2007000241A1 (en) * 2005-06-27 2007-01-04 Sanofi-Aventis Pyrazolopyridine derivatives as inhibitors of beta-adrenergic receptor kinase 1
EP1964840A1 (en) * 2007-02-28 2008-09-03 sanofi-aventis Imidazo[1,2-a]pyridines and their use as pharmaceuticals
JP2011524864A (ja) * 2008-05-30 2011-09-08 メルク・シャープ・エンド・ドーム・コーポレイション 新規な置換されたアザベンゾオキサゾール
TW201000099A (en) 2008-06-20 2010-01-01 Amgen Inc S1P1 receptor agonists and use thereof
EP2318415B1 (en) 2008-07-15 2013-02-20 Sanofi Oxazolopyrimidines as edg-1 receptor agonists
TWI517851B (zh) 2010-01-13 2016-01-21 賽諾菲阿凡提斯公司 含２，５，７－經取代唑并嘧啶環之雜環羧酸衍生物
TWI485153B (zh) 2010-01-13 2015-05-21 Sanofi Aventis ２，５，７－經取代唑并嘧啶衍生物
AR079981A1 (es) 2010-01-13 2012-03-07 Sanofi Aventis Derivados de acido carboxilico que comprenden un anillo de oxoazolopirimidina 2,5,7- sustituido
AU2011206615B2 (en) * 2010-01-14 2015-03-19 Sanofi Carboxylic acid derivatives having A 2,5-substituted oxazolopyrimidine ring
CN102834399B (zh) 2010-01-14 2015-04-22 赛诺菲 具有2,5-取代的*唑并嘧啶环的杂环羧酸衍生物
MY159857A (en) 2010-01-14 2017-02-15 Sanofi Sa 2,5-substituted oxazolopyrimidine derivatives
US9321787B2 (en) 2011-07-07 2016-04-26 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-d]pyrimidine ring
US8580816B2 (en) 2011-07-07 2013-11-12 Sanofi Carboxylic acid derivatives having an oxazolo[5,4-b]pyridine ring
US8907093B2 (en) 2011-07-07 2014-12-09 Sanofi Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring
US8735402B2 (en) 2011-07-07 2014-05-27 Sanofi Cycloalkyloxycarboxylic acid derivatives

Also Published As

Publication number Publication date
US9321787B2 (en) 2016-04-26
DK2729471T3 (en) 2015-08-10
US20130023544A1 (en) 2013-01-24
HK1192240A1 (en) 2014-08-15
PT2729471E (pt) 2015-09-16
MX2014000022A (es) 2014-02-19
EP2729471A1 (de) 2014-05-14
EP2729471B1 (de) 2015-05-06
JP2014518248A (ja) 2014-07-28
CN103781792A (zh) 2014-05-07
CA2841226C (en) 2019-11-12
RU2014104230A (ru) 2015-08-20
CN103781792B (zh) 2016-06-29
AU2012280207B2 (en) 2017-03-09
KR20140061385A (ko) 2014-05-21
IL230258A (en) 2016-08-31
ES2544620T3 (es) 2015-09-02
BR112014000118A2 (pt) 2017-01-10
JP5913585B2 (ja) 2016-04-27
RU2609008C2 (ru) 2017-01-30
MY164134A (en) 2017-11-30
AU2012280207A1 (en) 2014-01-23
CA2841226A1 (en) 2013-01-10
WO2013004827A1 (de) 2013-01-10

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