MX360783B - Proceso para la manufactura de isavuconazol o ravuconazol. - Google Patents

Proceso para la manufactura de isavuconazol o ravuconazol.

Info

Publication number
MX360783B
MX360783B MX2015000744A MX2015000744A MX360783B MX 360783 B MX360783 B MX 360783B MX 2015000744 A MX2015000744 A MX 2015000744A MX 2015000744 A MX2015000744 A MX 2015000744A MX 360783 B MX360783 B MX 360783B
Authority
MX
Mexico
Prior art keywords
isavuconazole
ravuconazole
manufacture
resolution
diastereomerically
Prior art date
Application number
MX2015000744A
Other languages
English (en)
Spanish (es)
Other versions
MX2015000744A (es
Inventor
Van Summeren Ruben
Vaessen Harrie
Mink Daniel
Waser Mario
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of MX2015000744A publication Critical patent/MX2015000744A/es
Publication of MX360783B publication Critical patent/MX360783B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Enzymes And Modification Thereof (AREA)
MX2015000744A 2012-08-07 2013-07-31 Proceso para la manufactura de isavuconazol o ravuconazol. MX360783B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12179540 2012-08-07
PCT/EP2013/066071 WO2014023623A1 (en) 2012-08-07 2013-07-31 Process for the manufacture of isavuconazole or ravuconazole

Publications (2)

Publication Number Publication Date
MX2015000744A MX2015000744A (es) 2015-04-14
MX360783B true MX360783B (es) 2018-11-16

Family

ID=48979725

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000744A MX360783B (es) 2012-08-07 2013-07-31 Proceso para la manufactura de isavuconazol o ravuconazol.

Country Status (15)

Country Link
US (2) US9783508B2 (enExample)
EP (1) EP2882723B1 (enExample)
JP (1) JP6334529B2 (enExample)
KR (1) KR102129150B1 (enExample)
CN (1) CN104507917B (enExample)
BR (1) BR112015002526B1 (enExample)
CA (1) CA2878361C (enExample)
ES (1) ES2616412T3 (enExample)
HR (1) HRP20170171T1 (enExample)
HU (1) HUE031679T2 (enExample)
MX (1) MX360783B (enExample)
PL (1) PL2882723T3 (enExample)
PT (1) PT2882723T (enExample)
SI (1) SI2882723T1 (enExample)
WO (1) WO2014023623A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105801500B (zh) * 2014-12-31 2018-08-24 四川科伦药物研究院有限公司 拆分艾沙康唑中间化合物消旋体的方法
CN106317044A (zh) * 2015-06-30 2017-01-11 刘玫君 一种制造艾沙康唑或雷夫康唑的方法
CN104961695A (zh) * 2015-07-27 2015-10-07 成都塞恩斯医药科技有限公司 一种艾沙康唑和雷夫康唑中间体的制备方法
CN106467534B (zh) * 2015-08-17 2019-10-11 江苏奥赛康药业有限公司 一种硫酸艾沙康唑鎓化合物及其药物组合物
CN105907832B (zh) * 2015-12-02 2019-07-12 成都师范学院 一种酶法拆分艾沙康唑中间体的方法
CN108452848B (zh) * 2016-02-24 2020-12-11 上海兰立生物科技有限公司 一种催化剂
WO2018200214A2 (en) * 2017-04-27 2018-11-01 Codexis, Inc. Ketoreductase polypeptides and polynucleotides
WO2021245590A1 (en) * 2020-06-04 2021-12-09 Metrochem Api Private Limited An improved process for the preparation of triazole derivatives
CN111574444A (zh) * 2020-07-07 2020-08-25 安徽贝克生物制药有限公司 一种贝达喹啉的制备方法
CN116478103B (zh) * 2023-03-24 2025-07-25 四川澄华生物科技有限公司 一种拆分艾沙康唑中间体4的方法
CN119661453B (zh) * 2025-02-17 2025-04-22 四川澄华生物科技有限公司 一种制备艾沙康唑的主链中间体的方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8510195D0 (en) * 1985-04-22 1985-05-30 Ici Plc Heterocyclic compounds
US5134152A (en) 1989-12-07 1992-07-28 Sankyo Company, Limited Oxetane derivatives and their use as anti-fungal or fungicidal agents
JP2887523B2 (ja) * 1990-11-30 1999-04-26 富山化学工業株式会社 新規なトリアゾール誘導体およびその塩
GB9107055D0 (en) * 1991-04-04 1991-05-22 Pfizer Ltd Triazole antifungal agents
JP4208269B2 (ja) * 1996-10-01 2009-01-14 東芝ソリューション株式会社 異種物混入検査方法及びそのシステム
AU7937998A (en) 1997-07-08 1999-02-08 Sankyo Company Limited Antifungal triazole compounds
WO1999045008A1 (en) 1998-03-06 1999-09-10 F. Hoffmann-La Roche Ag 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity
MXPA03010914A (es) 2001-06-26 2004-02-17 Basilea Pharmaceutica Ag DERIVADOS DE HALOFENILO INTERMEDIARIOS Y SU USO EN UN PROCESO PARA LA PREPARACIoN DE DERIVADOS DE AZOL.
WO2007062542A2 (en) 2005-12-01 2007-06-07 Basilea Pharmaceutica Ag Process for the manufacture of epoxybutanol intermediates
GB0712972D0 (en) 2007-07-04 2007-08-15 Glaxosmithkline Consumer Healt Formulation
ES2652559T3 (es) 2007-07-04 2018-02-05 Dpx Holdings B.V. Preparación de una esterasa
CN102344457B (zh) 2007-09-12 2015-07-22 杏林制药株式会社 作为 gsk-3 抑制剂的螺环状氨基喹诺酮
EP2289868B1 (en) 2008-06-25 2014-08-13 Daiichi Sankyo Company, Limited Carboxylic acid compound
SI2298747T1 (sl) * 2008-07-03 2017-08-31 Astellas Pharma Inc. Derivat triazola ali njegova sol
US8921080B2 (en) 2009-04-24 2014-12-30 Dsm Ip Assets B.V. Pig liver esterases
US8207352B2 (en) * 2009-10-08 2012-06-26 Drug Process Licensing Associates LLC Process for the manufacture of enantiomerically pure antifungal azoles as ravuconazole and isavuconazole
WO2011145669A1 (ja) * 2010-05-19 2011-11-24 大日本住友製薬株式会社 アミド誘導体

Also Published As

Publication number Publication date
JP6334529B2 (ja) 2018-05-30
KR20150037875A (ko) 2015-04-08
CA2878361A1 (en) 2014-02-13
CN104507917A (zh) 2015-04-08
PT2882723T (pt) 2017-02-23
EP2882723A1 (en) 2015-06-17
WO2014023623A1 (en) 2014-02-13
KR102129150B1 (ko) 2020-07-02
CN104507917B (zh) 2017-10-17
ES2616412T3 (es) 2017-06-13
US20150239852A1 (en) 2015-08-27
US9783508B2 (en) 2017-10-10
BR112015002526A2 (pt) 2018-06-12
MX2015000744A (es) 2015-04-14
US20190077771A1 (en) 2019-03-14
EP2882723B1 (en) 2016-11-16
JP2015527345A (ja) 2015-09-17
BR112015002526B1 (pt) 2022-09-06
CA2878361C (en) 2020-09-22
PL2882723T3 (pl) 2017-05-31
HRP20170171T1 (hr) 2017-04-07
SI2882723T1 (sl) 2017-04-26
HUE031679T2 (en) 2017-07-28
US10590092B2 (en) 2020-03-17

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