MX359554B - Microesferas cristalinas y proceso para fabricacion de las mismas. - Google Patents

Microesferas cristalinas y proceso para fabricacion de las mismas.

Info

Publication number
MX359554B
MX359554B MX2014012805A MX2014012805A MX359554B MX 359554 B MX359554 B MX 359554B MX 2014012805 A MX2014012805 A MX 2014012805A MX 2014012805 A MX2014012805 A MX 2014012805A MX 359554 B MX359554 B MX 359554B
Authority
MX
Mexico
Prior art keywords
microspheres
manufacturing
same
api
manufacture
Prior art date
Application number
MX2014012805A
Other languages
English (en)
Spanish (es)
Other versions
MX2014012805A (es
Inventor
W Propst Cecil
W Meadows Marc
S Todd Michael
Original Assignee
Spi Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spi Pharma Inc filed Critical Spi Pharma Inc
Publication of MX2014012805A publication Critical patent/MX2014012805A/es
Publication of MX359554B publication Critical patent/MX359554B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MX2014012805A 2012-04-25 2013-04-25 Microesferas cristalinas y proceso para fabricacion de las mismas. MX359554B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261638073P 2012-04-25 2012-04-25
US201361783603P 2013-03-14 2013-03-14
PCT/US2013/038257 WO2013163453A1 (en) 2012-04-25 2013-04-25 Crystalline microspheres and the process for manufacturing the same

Publications (2)

Publication Number Publication Date
MX2014012805A MX2014012805A (es) 2015-01-22
MX359554B true MX359554B (es) 2018-10-02

Family

ID=49483900

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014012805A MX359554B (es) 2012-04-25 2013-04-25 Microesferas cristalinas y proceso para fabricacion de las mismas.

Country Status (9)

Country Link
US (5) US20150140097A1 (enExample)
EP (2) EP3583935A1 (enExample)
JP (2) JP6577865B2 (enExample)
BR (1) BR112014026351B1 (enExample)
CA (1) CA2871429C (enExample)
ES (1) ES2729035T3 (enExample)
IN (1) IN2014DN09416A (enExample)
MX (1) MX359554B (enExample)
WO (1) WO2013163453A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL219362A (en) 2012-04-23 2017-04-30 Verint Systems Ltd A system and method for predicting threatened points of interest
CA2871429C (en) 2012-04-25 2018-07-31 Spi Pharma, Inc. Crystalline microspheres and the process for manufacturing the same
US10560842B2 (en) 2015-01-28 2020-02-11 Verint Systems Ltd. System and method for combined network-side and off-air monitoring of wireless networks
IL242354B (en) 2015-10-29 2019-09-26 Verint Systems Ltd System and method for identifying genuine base stations that serve rogue base stations
IL245299B (en) 2016-04-25 2021-05-31 Verint Systems Ltd A system and method for decoding communication transmitted in a wireless local communication network
JP2022523510A (ja) * 2019-01-31 2022-04-25 エレクトロフィ，インコーポレイテッド 粒子形成及び形態構造
US10639312B1 (en) * 2019-12-06 2020-05-05 Edenbridge Pharmaceuticals, LLC Finished pharmaceutical dosage form of a methenamine salt such as methenamine mandelate

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820627A (en) * 1986-03-24 1989-04-11 Em Diagnostic Systems, Inc. Method of preparing particles suitable for tabletting into diagnostic reagents
JPH0192403A (ja) 1987-09-30 1989-04-11 Aprica Kassai Inc 使い捨ておむつ
FR2670398B1 (fr) * 1990-12-14 1995-02-17 Roquette Freres Composition pulverulente directement compressible et procede d'obtention.
US5573783A (en) 1995-02-13 1996-11-12 Nano Systems L.L.C. Redispersible nanoparticulate film matrices with protective overcoats
US6548095B1 (en) 1996-08-24 2003-04-15 Südzucker Aktiengesellschaft Sugar-free compressed products
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
US5780055A (en) 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension
JPH1092403A (ja) 1996-09-17 1998-04-10 Sanyo Electric Co Ltd 電池収納機構及びこれを具えた電子機器
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
GB9716432D0 (en) * 1997-08-05 1997-10-08 Cerestar Holding Bv Tableting of erythritol
JP2000128774A (ja) 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2002035991A2 (en) * 2000-10-30 2002-05-10 The Board Of Regents, The University Of Texas System Spherical particles produced by a hot-melt extrusion/spheronization process
US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
ES2334991T3 (es) * 2002-03-26 2010-03-18 Teva Pharmaceutical Industries Ltd. Microparticulas de farmaco.
GB0228826D0 (en) * 2002-12-11 2003-01-15 Okpala Joseph Hair technology in creating particles with improved delivery capabilities
MXPA05008187A (es) * 2003-01-29 2006-03-30 Spi Polyols Inc Composiciones de granulos de poliol y procesos de manufactura.
JP2007508240A (ja) * 2003-07-22 2007-04-05 バクスター・インターナショナル・インコーポレイテッド 低分子量有機分子の小球状粒子ならびにその調製方法および使用方法
US20070092562A1 (en) 2003-10-28 2007-04-26 Spi Pharma, Inc. Product and process for increasing compactibility of carbohydrates
WO2005044193A2 (en) * 2003-10-28 2005-05-19 Spi Pharma, Inc. Product and process for increasing compactibility of carbohydrates
EP1689368B1 (en) 2003-12-04 2016-09-28 Bend Research, Inc Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions
JP5634009B2 (ja) * 2004-05-12 2014-12-03 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ タンパク質を含み、そして高濃度のタンパク質で注射性能を示すミクロスフェア
WO2006058250A2 (en) 2004-11-24 2006-06-01 Spi Pharma, Inc. Orally disintegrating compositions
WO2006109653A1 (ja) * 2005-04-06 2006-10-19 Sanyo Chemical Industries, Ltd. 樹脂粒子および樹脂分散体
JP2007217651A (ja) * 2006-02-20 2007-08-30 Daicel Chem Ind Ltd 環状ポリオレフィン系樹脂の球状粒子およびその製造方法
ES2358178T3 (es) 2006-08-01 2011-05-06 The Procter And Gamble Company Partícula liberadora que contiene un agente beneficioso.
WO2008065504A1 (en) 2006-11-30 2008-06-05 Pfizer Products Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
WO2008094877A2 (en) 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
US8883307B2 (en) 2007-05-28 2014-11-11 Mitsubishi Shoji Foodtech Co., Ltd. Spherical particle of crystalline mannitol
JP5258268B2 (ja) 2007-11-19 2013-08-07 フロイント産業株式会社 球形粒の製造方法
JP5650532B2 (ja) * 2008-08-18 2015-01-07 三菱商事フードテック株式会社 新規マンニトール打錠用賦形剤
WO2010104563A2 (en) 2009-03-09 2010-09-16 Spi Pharma, Inc. Highly compactable and durable direct compression excipients and excipient systems
BRPI1011412A8 (pt) * 2009-05-08 2018-01-02 Orexo Ab composição para liberação sustentada de droga compreendendo aglutinante geopolimérico
JP2011157348A (ja) * 2010-01-05 2011-08-18 Fuji Chem Ind Co Ltd 崩壊性高強度球状粒子組成物
DE102010045479A1 (de) 2010-09-16 2014-10-30 Brace Capital Gmbh Verfahren zur Mikroverkapselung, Herstellung von festen Formen mehrphasiger mischbarer und nichtmischbarer Materialien und Methode zur Herstellung vorgenannter Systeme
MX364560B (es) 2010-09-20 2019-05-02 Spi Pharma Inc Star Proceso de microencapsulacion y producto.
CA2871429C (en) 2012-04-25 2018-07-31 Spi Pharma, Inc. Crystalline microspheres and the process for manufacturing the same

Also Published As

Publication number Publication date
US9089487B2 (en) 2015-07-28
BR112014026351A2 (pt) 2017-06-27
EP2841057B1 (en) 2019-03-20
EP2841057A4 (en) 2015-09-16
US20220151932A1 (en) 2022-05-19
CA2871429A1 (en) 2013-10-31
IN2014DN09416A (enExample) 2015-07-17
JP2015514809A (ja) 2015-05-21
CA2871429C (en) 2018-07-31
EP2841057A1 (en) 2015-03-04
US12233163B2 (en) 2025-02-25
ES2729035T3 (es) 2019-10-29
US10245232B2 (en) 2019-04-02
US11278496B2 (en) 2022-03-22
WO2013163453A1 (en) 2013-10-31
BR112014026351B1 (pt) 2022-09-27
JP6577865B2 (ja) 2019-09-18
US20150140097A1 (en) 2015-05-21
JP2019112438A (ja) 2019-07-11
US20190224126A1 (en) 2019-07-25
US20140099372A1 (en) 2014-04-10
EP3583935A1 (en) 2019-12-25
MX2014012805A (es) 2015-01-22
US20160015640A1 (en) 2016-01-21

Similar Documents

Publication Publication Date Title
MX359554B (es) Microesferas cristalinas y proceso para fabricacion de las mismas.
MX389751B (es) Composición farmacéutica y administraciones de la misma.
IN2015KN00262A (enExample)
TN2011000370A1 (en) Alkylamine-substituted dicyanopyridine and amino acid ester prodrugs thereof
MX348823B (es) Formulaciones estables de linaclotida.
PH12013501143A1 (en) Substituted 1-benzylcycloalkylcarboxlic acids and use thereof
MX2013004759A (es) Compuestos de oxima como agentes de elevacion de colesterol de lipoproteina de alta densidad (hdl).
WO2014016848A3 (en) Solid forms of tyrosine kinase inhibitors, process for the preparation and their pharmaceutical composition thereof
WO2012040804A3 (en) Synergistic combinations of triazoles, strobilurins and benzimidazoles, uses, formulations, production processes and applications using the same
NZ628451A (en) Dehydrated plant-derived products and methods for making the same
MX350545B (es) Partículas de suministro con pluralidad de núcleos.
WO2013134534A3 (en) Solid state forms of cabazitaxel and processes for preparation thereof
WO2012101653A3 (en) Modified release pharmaceutical compositions memantine
TN2013000386A1 (en) Suspension type topical formulations comprising cyclic depsipeptide
ZA201500362B (en) Novel compound having ability to inhibit 11b-hsd1 enzyme or pharmaceutically acceptable salt thereof, method for producing same, and pharmaceutical composition containing same as active ingredient
MX2016001422A (es) Composicion farmaceutica de fingolimod.
TN2015000267A1 (en) Solid unit with high fexofenadine content and process for the preparation thereof
MX2013013079A (es) Composiciones que comprenden un agente antibacterial y tazobactam.
WO2016195194A3 (ko) 신규한 tlr2 길항제
PH12013500980A1 (en) Complex formulation comprising lercanidipine hydrochloride and valsartan and method for the preparation thereof
WO2012007758A3 (en) Pharmaceutical formulations
PH12013502080A1 (en) Modified release pharmaceutical compositions of desvenlafaxine
CA2865484A1 (en) Stabilized controlled-release pharmaceutical composition comprising gliclazide
WO2011139255A3 (en) Pharmaceutical compositions comprising cefetamet
WO2012023145A3 (en) Prasugrel hydrochloride crystalline particles

Legal Events

Date Code Title Description
FG Grant or registration