IN2014DN09416A - - Google Patents

Info

Publication number
IN2014DN09416A
IN2014DN09416A IN9416DEN2014A IN2014DN09416A IN 2014DN09416 A IN2014DN09416 A IN 2014DN09416A IN 9416DEN2014 A IN9416DEN2014 A IN 9416DEN2014A IN 2014DN09416 A IN2014DN09416 A IN 2014DN09416A
Authority
IN
India
Prior art keywords
microspheres
api
manufacture
present
dispersions
Prior art date
Application number
Other languages
English (en)
Inventor
Cecil W Propst
Marc W Meadows
Michael S Todd
Original Assignee
Spi Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spi Pharma Inc filed Critical Spi Pharma Inc
Publication of IN2014DN09416A publication Critical patent/IN2014DN09416A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IN9416DEN2014 2012-04-25 2013-04-25 IN2014DN09416A (enExample)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261638073P 2012-04-25 2012-04-25
US201361783603P 2013-03-14 2013-03-14
PCT/US2013/038257 WO2013163453A1 (en) 2012-04-25 2013-04-25 Crystalline microspheres and the process for manufacturing the same

Publications (1)

Publication Number Publication Date
IN2014DN09416A true IN2014DN09416A (enExample) 2015-07-17

Family

ID=49483900

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9416DEN2014 IN2014DN09416A (enExample) 2012-04-25 2013-04-25

Country Status (9)

Country Link
US (5) US9089487B2 (enExample)
EP (2) EP3583935A1 (enExample)
JP (2) JP6577865B2 (enExample)
BR (1) BR112014026351B1 (enExample)
CA (1) CA2871429C (enExample)
ES (1) ES2729035T3 (enExample)
IN (1) IN2014DN09416A (enExample)
MX (1) MX359554B (enExample)
WO (1) WO2013163453A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL219362A (en) 2012-04-23 2017-04-30 Verint Systems Ltd A system and method for predicting threatened points of interest
EP3583935A1 (en) 2012-04-25 2019-12-25 SPI Pharma, INC. Crystalline microspheres and the process for manufacturing the same
US10560842B2 (en) 2015-01-28 2020-02-11 Verint Systems Ltd. System and method for combined network-side and off-air monitoring of wireless networks
IL242354B (en) 2015-10-29 2019-09-26 Verint Systems Ltd System and method for identifying genuine base stations that serve rogue base stations
IL245299B (en) 2016-04-25 2021-05-31 Verint Systems Ltd A system and method for decoding communication transmitted in a wireless local communication network
AU2020214626B2 (en) 2019-01-31 2025-10-16 Halozyme Hypercon, Inc. Particle formation and morphology
AU2020344675B2 (en) 2019-09-13 2026-06-25 Halozyme Hypercon, Inc. Compositions and methods for the delivery of therapeutic biologics for treatment of disease
US10639312B1 (en) * 2019-12-06 2020-05-05 Edenbridge Pharmaceuticals, LLC Finished pharmaceutical dosage form of a methenamine salt such as methenamine mandelate

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820627A (en) * 1986-03-24 1989-04-11 Em Diagnostic Systems, Inc. Method of preparing particles suitable for tabletting into diagnostic reagents
JPH0192403A (ja) 1987-09-30 1989-04-11 Aprica Kassai Inc 使い捨ておむつ
FR2670398B1 (fr) * 1990-12-14 1995-02-17 Roquette Freres Composition pulverulente directement compressible et procede d'obtention.
US5573783A (en) 1995-02-13 1996-11-12 Nano Systems L.L.C. Redispersible nanoparticulate film matrices with protective overcoats
US6548095B1 (en) 1996-08-24 2003-04-15 Südzucker Aktiengesellschaft Sugar-free compressed products
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation
US5780055A (en) 1996-09-06 1998-07-14 University Of Maryland, Baltimore Cushioning beads and tablet comprising the same capable of forming a suspension
JPH1092403A (ja) 1996-09-17 1998-04-10 Sanyo Electric Co Ltd 電池収納機構及びこれを具えた電子機器
JP3447042B2 (ja) * 1997-07-23 2003-09-16 フロイント産業株式会社 単一物質球形粒の製造方法
GB9716432D0 (en) * 1997-08-05 1997-10-08 Cerestar Holding Bv Tableting of erythritol
JP2000128774A (ja) 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
WO2002035991A2 (en) * 2000-10-30 2002-05-10 The Board Of Regents, The University Of Texas System Spherical particles produced by a hot-melt extrusion/spheronization process
US20030129250A1 (en) * 2001-11-20 2003-07-10 Advanced Inhalation Research Inc. Particulate compositions for improving solubility of poorly soluble agents
US7118765B2 (en) 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
PT1487416E (pt) * 2002-03-26 2010-01-25 Teva Pharma Micropartículas de fármacos
GB0228826D0 (en) * 2002-12-11 2003-01-15 Okpala Joseph Hair technology in creating particles with improved delivery capabilities
EP1589824A4 (en) * 2003-01-29 2006-12-27 Spi Polyols Inc POLYOLGRANULATE COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
WO2005009375A2 (en) 2003-07-22 2005-02-03 Baxter International Inc. Small spherical particles of low molecular weight organic molecules and methods of preparation and use thereof
US20070092562A1 (en) 2003-10-28 2007-04-26 Spi Pharma, Inc. Product and process for increasing compactibility of carbohydrates
EP1677736A4 (en) * 2003-10-28 2007-09-12 Spi Pharma Inc PRODUCT AND PROCESS FOR INCREASING COMPACTION ABILITY FOR CARBOHYDRATES
JP2007513147A (ja) 2003-12-04 2007-05-24 ファイザー・プロダクツ・インク 押し出し機を使用して、好ましくはポロキサマーとグリセリドを含有する多粒子結晶性医薬組成物を製造するための噴霧凝結方法
CN103393601A (zh) * 2004-05-12 2013-11-20 巴克斯特国际公司 含有蛋白并在高浓度蛋白下显示可注射性的微球体
EP1817009A2 (en) 2004-11-24 2007-08-15 Spi Pharma, Inc. Orally disintegrating compositions
CN101155859B (zh) 2005-04-06 2012-04-25 三洋化成工业株式会社 树脂颗粒和树脂分散体
JP2007217651A (ja) 2006-02-20 2007-08-30 Daicel Chem Ind Ltd 環状ポリオレフィン系樹脂の球状粒子およびその製造方法
JP2009544812A (ja) 2006-08-01 2009-12-17 ザ プロクター アンド ギャンブル カンパニー 有益剤含有デリバリー粒子
US10357462B2 (en) 2006-11-30 2019-07-23 Ben Research, Inc. Multiparticulates of spray-coated drug and polymer on a meltable core
WO2008094877A2 (en) 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
BRPI0810978B1 (pt) * 2007-05-28 2021-05-25 Mitsubishi Shoji Foodtech Co., Ltd Partícula esférica de manitol cristalino
JP5258268B2 (ja) 2007-11-19 2013-08-07 フロイント産業株式会社 球形粒の製造方法
CA2734847C (en) * 2008-08-18 2016-08-30 Mitsubishi Shoji Foodtech Co., Ltd. Novel excipient for mannitol tableting
AU2010223105B2 (en) 2009-03-09 2016-05-12 Spi Pharma, Inc. Highly compactable and durable direct compression excipients and excipient systems
WO2010128300A1 (en) * 2009-05-08 2010-11-11 Aduro Materials Ab Composition for sustained drug delivery comprising geopolymeric binder
JP2011157348A (ja) * 2010-01-05 2011-08-18 Fuji Chem Ind Co Ltd 崩壊性高強度球状粒子組成物
DE102010045479A1 (de) 2010-09-16 2014-10-30 Brace Capital Gmbh Verfahren zur Mikroverkapselung, Herstellung von festen Formen mehrphasiger mischbarer und nichtmischbarer Materialien und Methode zur Herstellung vorgenannter Systeme
US10561621B2 (en) 2010-09-20 2020-02-18 Diane Goll Microencapsulation process and product
EP3583935A1 (en) 2012-04-25 2019-12-25 SPI Pharma, INC. Crystalline microspheres and the process for manufacturing the same

Also Published As

Publication number Publication date
BR112014026351B1 (pt) 2022-09-27
US10245232B2 (en) 2019-04-02
US9089487B2 (en) 2015-07-28
BR112014026351A2 (pt) 2017-06-27
JP6577865B2 (ja) 2019-09-18
EP2841057B1 (en) 2019-03-20
CA2871429C (en) 2018-07-31
US20150140097A1 (en) 2015-05-21
US20160015640A1 (en) 2016-01-21
MX2014012805A (es) 2015-01-22
EP2841057A1 (en) 2015-03-04
US20140099372A1 (en) 2014-04-10
CA2871429A1 (en) 2013-10-31
MX359554B (es) 2018-10-02
US12233163B2 (en) 2025-02-25
US20220151932A1 (en) 2022-05-19
JP2019112438A (ja) 2019-07-11
US20190224126A1 (en) 2019-07-25
JP2015514809A (ja) 2015-05-21
EP3583935A1 (en) 2019-12-25
ES2729035T3 (es) 2019-10-29
WO2013163453A1 (en) 2013-10-31
EP2841057A4 (en) 2015-09-16
US11278496B2 (en) 2022-03-22

Similar Documents

Publication Publication Date Title
MX359554B (es) Microesferas cristalinas y proceso para fabricacion de las mismas.
MX389751B (es) Composición farmacéutica y administraciones de la misma.
MX348823B (es) Formulaciones estables de linaclotida.
WO2011099832A3 (en) Novel benzimidazole compound, preparation method thereof and pharmaceutical composition comprising the same
WO2012088266A3 (en) Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
MY196014A (en) Eutectic Formulations of Cyclobenzaprine Hydrochloride and Amitriptyline Hydrochloride
SG11201406141UA (en) Immortalized stem cells and medicinal composition and medicinal preparation comprising product thereof as active ingredient
PH12015501096A1 (en) Composition for immediate and extended release
NZ628451A (en) Dehydrated plant-derived products and methods for making the same
SG10201902203VA (en) Eutectic formulations of cyclobenzaprine hydrochloride
PH12014502512A1 (en) Topical pharmaceutical compositions comprising terbinafine and urea
WO2013134534A3 (en) Solid state forms of cabazitaxel and processes for preparation thereof
GEP20186825B (en) Formulation comprising hypolipidemic agent
PH12012502083A1 (en) Manufacturing of active-free granules and tablets comprising the same
NZ708821A (en) Lfa-1 inhibitor formulations
TN2013000386A1 (en) Suspension type topical formulations comprising cyclic depsipeptide
MX369549B (es) Un proceso para la fabricación de núcleos de tabletas duros con recubrimiento.
MX2016001422A (es) Composicion farmaceutica de fingolimod.
TN2015000267A1 (en) Solid unit with high fexofenadine content and process for the preparation thereof
TR201009167A2 (tr) Sefalosporin içeren farmasötik granüller.
PH12016502544B1 (en) Pharmaceutical preparation containing entecavir as active ingredient, and preparation method therefor
MX356373B (es) Composiciones que comprenden un agente antibacterial y tazobactam.
WO2016195194A3 (ko) 신규한 tlr2 길항제
PH12013500980A1 (en) Complex formulation comprising lercanidipine hydrochloride and valsartan and method for the preparation thereof
WO2012007758A3 (en) Pharmaceutical formulations