MX359210B - Composición de combinación de pac-1 y tamoxifeno. - Google Patents

Composición de combinación de pac-1 y tamoxifeno.

Info

Publication number
MX359210B
MX359210B MX2014010713A MX2014010713A MX359210B MX 359210 B MX359210 B MX 359210B MX 2014010713 A MX2014010713 A MX 2014010713A MX 2014010713 A MX2014010713 A MX 2014010713A MX 359210 B MX359210 B MX 359210B
Authority
MX
Mexico
Prior art keywords
compounds
procaspase
activation
combination therapy
combinations
Prior art date
Application number
MX2014010713A
Other languages
English (en)
Spanish (es)
Other versions
MX2014010713A (es
Inventor
j hergenrother Paul
C Botham Rachel
M Fan Timothy
j gilbert Mark
K Handley Michael
S Roth Howard
M Tarasow Theodore
Original Assignee
Univ Illinois
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Illinois filed Critical Univ Illinois
Publication of MX2014010713A publication Critical patent/MX2014010713A/es
Publication of MX359210B publication Critical patent/MX359210B/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K9/007—Pulmonary tract; Aromatherapy
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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    • A61K9/2022—Organic macromolecular compounds
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    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/4965—Non-condensed pyrazines
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
MX2014010713A 2012-03-06 2013-03-06 Composición de combinación de pac-1 y tamoxifeno. MX359210B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261607098P 2012-03-06 2012-03-06
PCT/US2013/029405 WO2013134407A2 (en) 2012-03-06 2013-03-06 Procaspase 3 activation by combination therapy

Publications (2)

Publication Number Publication Date
MX2014010713A MX2014010713A (es) 2015-03-10
MX359210B true MX359210B (es) 2018-09-19

Family

ID=49117502

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2014010713A MX359210B (es) 2012-03-06 2013-03-06 Composición de combinación de pac-1 y tamoxifeno.
MX2017013045A MX365392B (es) 2012-03-06 2013-03-06 Composición de combinación de pac-1 y doxorrubicina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2017013045A MX365392B (es) 2012-03-06 2013-03-06 Composición de combinación de pac-1 y doxorrubicina.

Country Status (14)

Country Link
US (4) US9399035B2 (enExample)
EP (2) EP2822558B1 (enExample)
JP (1) JP6172865B2 (enExample)
KR (1) KR102074530B1 (enExample)
CN (1) CN104507479B (enExample)
AU (1) AU2016213862B2 (enExample)
BR (1) BR112014022103B1 (enExample)
CA (1) CA2866021C (enExample)
DK (1) DK2822558T3 (enExample)
ES (1) ES2774930T3 (enExample)
IN (1) IN2014MN01945A (enExample)
MX (2) MX359210B (enExample)
RU (1) RU2659936C2 (enExample)
WO (2) WO2013134407A2 (enExample)

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CN107249580A (zh) 2014-12-05 2017-10-13 An2H探索有限公司 帕金连接酶活化方法和组合物
EP3302478B1 (en) * 2015-06-05 2021-11-17 The Board of Trustees of the University of Illinois Pac-1 combination therapy
KR101712638B1 (ko) 2015-08-19 2017-03-07 한국과학기술연구원 Pac-1을 이용한 단백질 발현 조절 시스템과 방법 및 pac-1을 유효성분 포함하는 독시사이클린 길항제
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US12090153B2 (en) 2018-10-05 2024-09-17 The Board Of Trustees Of The University Of Illinois Combination therapy for the treatment of uveal melanoma
KR20220016104A (ko) * 2019-05-30 2022-02-08 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 암 치료를 위한 프로카스파아제-3 활성화 및 면역요법

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EP4274558A1 (en) 2023-11-15
CA2866021C (en) 2020-09-22
BR112014022103A2 (enExample) 2017-08-22
EP2822558A2 (en) 2015-01-14
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CN104507479B (zh) 2017-08-18
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US10888560B2 (en) 2021-01-12
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