MX357227B - Nanoparticulas basadas en lipidos. - Google Patents
Nanoparticulas basadas en lipidos.Info
- Publication number
- MX357227B MX357227B MX2013011231A MX2013011231A MX357227B MX 357227 B MX357227 B MX 357227B MX 2013011231 A MX2013011231 A MX 2013011231A MX 2013011231 A MX2013011231 A MX 2013011231A MX 357227 B MX357227 B MX 357227B
- Authority
- MX
- Mexico
- Prior art keywords
- compositions
- lipid
- based nanoparticles
- amyloid
- liposomal
- Prior art date
Links
- 150000002632 lipids Chemical class 0.000 title abstract 2
- 239000002105 nanoparticle Substances 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 5
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 102000013455 Amyloid beta-Peptides Human genes 0.000 abstract 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1806—Suspensions, emulsions, colloids, dispersions
- A61K49/1812—Suspensions, emulsions, colloids, dispersions liposomes, polymersomes, e.g. immunoliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
- A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
- A61K49/0461—Dispersions, colloids, emulsions or suspensions
- A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Radiology & Medical Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161472605P | 2011-04-06 | 2011-04-06 | |
| PCT/US2012/032649 WO2012139080A2 (en) | 2011-04-06 | 2012-04-06 | Lipid-based nanoparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013011231A MX2013011231A (es) | 2015-03-05 |
| MX357227B true MX357227B (es) | 2018-07-02 |
Family
ID=46966277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013011231A MX357227B (es) | 2011-04-06 | 2012-04-06 | Nanoparticulas basadas en lipidos. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9801957B2 (https=) |
| EP (2) | EP2694116B1 (https=) |
| JP (3) | JP6212032B2 (https=) |
| KR (2) | KR102035187B1 (https=) |
| CN (1) | CN104144708B (https=) |
| AU (3) | AU2012239888B9 (https=) |
| BR (1) | BR112013025633A2 (https=) |
| CA (1) | CA2831480C (https=) |
| DK (1) | DK2694116T3 (https=) |
| ES (1) | ES2685824T3 (https=) |
| MX (1) | MX357227B (https=) |
| PL (1) | PL2694116T3 (https=) |
| PT (1) | PT2694116T (https=) |
| WO (1) | WO2012139080A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102035187B1 (ko) * | 2011-04-06 | 2019-11-08 | 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 지질-기반 나노입자들 |
| MX366972B (es) | 2012-01-20 | 2019-08-01 | Ananth Annapragada | Metodos y composiciones para caracterizar imagenes medicas en forma objetiva. |
| US9512092B2 (en) | 2013-12-12 | 2016-12-06 | Albert Einstein College Of Medicine, Inc. | Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof |
| AU2015330824A1 (en) * | 2014-10-08 | 2017-05-25 | Ananth Annapragada | MRI imaging of amyloid plaque using liposomes |
| GB201509934D0 (en) | 2015-06-08 | 2015-07-22 | King S College London | Nanoparticles |
| CN109414451B (zh) * | 2016-05-16 | 2022-08-12 | 德克萨斯大学系统董事会 | 用于作为纳米粒递送tRNA的组合物及其使用方法 |
| EP3548002B1 (en) * | 2016-11-30 | 2025-04-30 | Texas Children's Hospital | Hydrophilic fluorinated molecules for liposomal 19f mri probes with unique mr signatures |
| US20200261605A1 (en) * | 2019-01-24 | 2020-08-20 | Alzeca Biosciences, LLC | Functionalized liposomes for imaging misfolded proteins |
| CN115916263B (zh) * | 2020-01-29 | 2025-10-03 | 德克萨斯儿童医院 | 用于淀粉样蛋白沉积mri的靶向对比剂 |
| US11779664B2 (en) | 2020-02-12 | 2023-10-10 | Texas Children's Hospital | Targeted contrast agents for MRI of alpha-synuclein deposition |
| EP4103239A4 (en) * | 2020-02-12 | 2024-03-20 | Texas Children's Hospital | Targeted contrast agents for mri of alpha-synuclein deposition |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4331751A (en) * | 1980-11-17 | 1982-05-25 | Eastman Kodak Company | Electrically photosensitive materials and elements for photoelectrophoretic imaging processes |
| US5204085A (en) | 1985-01-08 | 1993-04-20 | Mallinckrodt Medical, Inc. | Method for enhancing the safety of metal-ligand chelates as X-ray contrast agents |
| US5674468A (en) | 1992-03-06 | 1997-10-07 | Nycomed Imaging As | Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons |
| WO1995026205A1 (en) | 1994-03-28 | 1995-10-05 | Nycomed Imaging A/S | Liposomes |
| US6071532A (en) | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
| DE60017787T2 (de) * | 1999-11-30 | 2006-01-05 | ARIZONA BOARD OF REGENTS, on behalf of THE UNIVERSITY OF ARIZONA, Tucson | Strahlung-sensitive liposomen |
| WO2002028441A2 (en) * | 2000-10-04 | 2002-04-11 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
| US6821504B2 (en) * | 2001-05-23 | 2004-11-23 | New York University | Detection of alzheimer's amyloid by magnetic resonance imaging |
| EP1480691A4 (en) | 2002-03-05 | 2007-11-28 | Univ State Cleveland | AGGLOMERATED PARTICLES FOR THE DISPOSAL OF A MEDICINAL PRODUCT IN AEROSOL FORM |
| EP1641742A4 (en) | 2003-05-01 | 2006-11-29 | Nst Neurosurvival Technologies | COMPOUNDS BINDING SELECTIVELY TO MEMBRANES OF APOPTOTIC CELLS |
| US7208174B2 (en) | 2003-12-18 | 2007-04-24 | Hoffmann-La Roche Inc. | Liposome compositions |
| US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
| US8357351B2 (en) | 2004-04-21 | 2013-01-22 | Ananth Annapragada | Nano-scale contrast agents and methods of use |
| US7713517B2 (en) | 2004-04-21 | 2010-05-11 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| WO2006026184A2 (en) * | 2004-08-20 | 2006-03-09 | Washington University | Blood brain barrier permeation peptides |
| JP2008513533A (ja) * | 2004-09-23 | 2008-05-01 | ゲルベ | Ｃｅｓｔイメージング用の造影剤封入システム |
| EP1888034A2 (en) * | 2005-05-26 | 2008-02-20 | Yissum Research Development Company, of The Hebrew University of Jerusalem | Compositions and methods using same for delivering agents into a target organ protected by a blood barrier |
| US20070160658A1 (en) * | 2005-10-20 | 2007-07-12 | The Penn State Research Foundation | Delivery system for diagnostic and therapeutic agents |
| WO2008054498A2 (en) * | 2006-04-07 | 2008-05-08 | The Board Of Trustees Of The University Of Illinois | Hydrophilic polymer-conjugated lipids for peptide and protein folding disorders |
| US20090123047A1 (en) | 2007-03-21 | 2009-05-14 | Yfantis Spyros A | Method and system for characterizing prostate images |
| EP1982733A1 (en) | 2007-04-17 | 2008-10-22 | Bayer Schering Pharma Aktiengesellschaft | Use of a contrast agent for magnetic resonance imaging of endoleaks |
| EP2182924A1 (en) | 2007-07-26 | 2010-05-12 | Nanoscan Imaging, Llc | Methods for imaging using improved nanoparticulate contrast agents |
| JP2011506325A (ja) | 2007-12-05 | 2011-03-03 | マーバル バイオサイエンシーズ インコーポレイテッド | ナノスケールのコントラスト剤及びその使用方法 |
| CA2711503A1 (en) | 2008-01-08 | 2009-07-16 | Biogenerix Ag | Glycoconjugation of polypeptides using oligosaccharyltransferases |
| ITMI20081052A1 (it) * | 2008-06-10 | 2009-12-11 | Univ Milano Bicocca | Liposomi in grado di legare efficacemente il peptide beta-amiloide |
| US20090311191A1 (en) | 2008-06-13 | 2009-12-17 | Ananth Annapragada | Imaging of atherosclerotic plaques using liposomal imaging agents |
| WO2010017094A2 (en) * | 2008-07-31 | 2010-02-11 | The General Hospital Corporation | CURCUMIN DERIVATIVES FOR AMYLOID-β PLAQUE IMAGING |
| AR074760A1 (es) | 2008-12-18 | 2011-02-09 | Metabolex Inc | Agonistas del receptor gpr120 y usos de los mismos en medicamentos para el tratamiento de diabetes y el sindrome metabolico. |
| WO2010107990A1 (en) * | 2009-03-19 | 2010-09-23 | Marval Biosciences, Inc. | Compositions and methods for enhancing contrast in imaging |
| US9334304B2 (en) * | 2009-04-02 | 2016-05-10 | The Johns Hopkins University | Self-assembling peptides bearing organic electronic functionality and applications employing the same |
| EP2501696B1 (en) | 2009-10-15 | 2016-12-28 | Guerbet | Imaging agents and their use for the diagnostic in vivo of neurodegenerative diseases, notably alzheimer's disease and derivative diseases |
| JP5746334B2 (ja) | 2010-06-16 | 2015-07-08 | シマベイ セラピューティクス， インコーポレーテッド | Ｇｐｒ１２０受容体作動薬及びその使用 |
| CN103429226A (zh) | 2011-03-02 | 2013-12-04 | 森苏林公司 | 囊泡组合物 |
| KR102035187B1 (ko) | 2011-04-06 | 2019-11-08 | 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 | 지질-기반 나노입자들 |
| GB201112056D0 (en) | 2011-07-14 | 2011-08-31 | Univ Leuven Kath | Antibodies |
| MX366972B (es) | 2012-01-20 | 2019-08-01 | Ananth Annapragada | Metodos y composiciones para caracterizar imagenes medicas en forma objetiva. |
| WO2013164763A2 (en) | 2012-04-30 | 2013-11-07 | Innovative Health Diagnostics | A biological complex specific for alzheimer's disease detection in vitro and use thereof |
| MX2015011677A (es) | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| AU2015330824A1 (en) | 2014-10-08 | 2017-05-25 | Ananth Annapragada | MRI imaging of amyloid plaque using liposomes |
-
2012
- 2012-04-06 KR KR1020197007384A patent/KR102035187B1/ko not_active Expired - Fee Related
- 2012-04-06 EP EP12767275.6A patent/EP2694116B1/en not_active Not-in-force
- 2012-04-06 CN CN201280017548.6A patent/CN104144708B/zh not_active Expired - Fee Related
- 2012-04-06 PT PT12767275T patent/PT2694116T/pt unknown
- 2012-04-06 MX MX2013011231A patent/MX357227B/es active IP Right Grant
- 2012-04-06 CA CA2831480A patent/CA2831480C/en not_active Expired - Fee Related
- 2012-04-06 EP EP18167725.3A patent/EP3366313A1/en not_active Withdrawn
- 2012-04-06 KR KR1020137029510A patent/KR101973063B1/ko not_active Expired - Fee Related
- 2012-04-06 US US13/441,816 patent/US9801957B2/en not_active Expired - Fee Related
- 2012-04-06 WO PCT/US2012/032649 patent/WO2012139080A2/en not_active Ceased
- 2012-04-06 ES ES12767275.6T patent/ES2685824T3/es active Active
- 2012-04-06 DK DK12767275.6T patent/DK2694116T3/en active
- 2012-04-06 BR BR112013025633A patent/BR112013025633A2/pt not_active Application Discontinuation
- 2012-04-06 PL PL12767275T patent/PL2694116T3/pl unknown
- 2012-04-06 AU AU2012239888A patent/AU2012239888B9/en not_active Ceased
- 2012-04-06 JP JP2014504057A patent/JP6212032B2/ja not_active Expired - Fee Related
-
2017
- 2017-09-14 JP JP2017176383A patent/JP6533813B2/ja not_active Expired - Fee Related
- 2017-09-21 AU AU2017232156A patent/AU2017232156C1/en not_active Ceased
-
2019
- 2019-05-27 JP JP2019098174A patent/JP2019151664A/ja active Pending
- 2019-10-08 AU AU2019246775A patent/AU2019246775A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |