MX356545B - Composicion esteril. - Google Patents

Composicion esteril.

Info

Publication number
MX356545B
MX356545B MX2014013818A MX2014013818A MX356545B MX 356545 B MX356545 B MX 356545B MX 2014013818 A MX2014013818 A MX 2014013818A MX 2014013818 A MX2014013818 A MX 2014013818A MX 356545 B MX356545 B MX 356545B
Authority
MX
Mexico
Prior art keywords
sterilized composition
sterilized
protein
composition
radiation
Prior art date
Application number
MX2014013818A
Other languages
English (en)
Other versions
MX2014013818A (es
Inventor
Kageyama Yukako
Fujinaga Kentaro
Yamaguchi Ayuko
Honda Susumu
Satake Makoto
Kaneko Hiroaki
Ishiwari Ayumi
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of MX2014013818A publication Critical patent/MX2014013818A/es
Publication of MX356545B publication Critical patent/MX356545B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Moulding By Coating Moulds (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Abstract

La presente invención se refiere a una composición estéril que comprende una proteína y un poliéster alifático y se esteriliza con radiación, en donde al menos parte de la proteína entra en el interior del poliéster alifático, y en donde la proteína se selecciona del grupo que consiste de fibrinógeno, enzimas, proteínas de transporte, proteínas de defensa, proteínas de toxinas, hormonas proteicas, factores de crecimiento y sus mezclas, siempre que la composición estéril en el estado de partículas finas que son capaces de pasar a través de mallas de 180 µm está excluida.
MX2014013818A 2012-05-14 2013-05-13 Composicion esteril. MX356545B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2012110765 2012-05-14
JP2012110390 2012-05-14
JP2013040593 2013-03-01
PCT/JP2013/063868 WO2013172468A1 (ja) 2012-05-14 2013-05-13 滅菌組成物

Publications (2)

Publication Number Publication Date
MX2014013818A MX2014013818A (es) 2015-05-11
MX356545B true MX356545B (es) 2018-06-01

Family

ID=49583866

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014013818A MX356545B (es) 2012-05-14 2013-05-13 Composicion esteril.

Country Status (18)

Country Link
US (1) US10071061B2 (es)
EP (1) EP2851085B1 (es)
JP (1) JP5746430B2 (es)
KR (1) KR102037555B1 (es)
CN (1) CN104284673B (es)
AU (1) AU2013261308B2 (es)
BR (1) BR112014028443B1 (es)
CA (1) CA2873602C (es)
DK (1) DK2851085T3 (es)
ES (1) ES2746300T3 (es)
HK (1) HK1204947A1 (es)
IN (1) IN2014DN09621A (es)
MX (1) MX356545B (es)
PL (1) PL2851085T3 (es)
PT (1) PT2851085T (es)
RU (1) RU2695522C2 (es)
TW (1) TWI636799B (es)
WO (1) WO2013172468A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5844894B2 (ja) * 2012-05-14 2016-01-20 帝人株式会社 シート成形体および止血材
EP3245871A1 (en) 2014-04-30 2017-11-22 Matoke Holdings Limited Antimicrobial compositions
US20180023217A1 (en) * 2015-02-03 2018-01-25 Matoke Holdings Limited Antimicrobial fibers and compositions
FR3036707B1 (fr) * 2015-05-29 2019-05-17 Maco Pharma Procede de sterilisation d'un lysat plaquettaire
GB201716986D0 (en) 2017-10-16 2017-11-29 Matoke Holdings Ltd Antimicrobial compositions
EP3919022A4 (en) 2019-01-31 2022-03-16 Cell-Medicine, Inc. MEDICAL INSTRUMENT WITH INORGANIC SALT-PROTEIN COMPOSITE

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2209937B (en) 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
JPH0622570B2 (ja) 1989-01-31 1994-03-30 多木化学株式会社 生体材料
US5225205A (en) 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
CH679207A5 (es) 1989-07-28 1992-01-15 Debiopharm Sa
US5439688A (en) 1989-07-28 1995-08-08 Debio Recherche Pharmaceutique S.A. Process for preparing a pharmaceutical composition
CA2033046C (en) 1990-01-12 1999-08-03 Lowell Saferstein Process for preparing a neutralized oxidized cellulose product and its method of use
MX9203083A (es) 1991-06-21 1994-08-31 Genetics Inst Formulaciones farmaceuticas de proteinas osteogenicas.
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
US5730933A (en) * 1996-04-16 1998-03-24 Depuy Orthopaedics, Inc. Radiation sterilization of biologically active compounds
US5945128A (en) 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
GB2344519B (en) * 1998-12-07 2004-05-19 Johnson & Johnson Medical Ltd Sterile therapeutic compositions
US8076448B2 (en) 2006-10-11 2011-12-13 Tolmar Therapeutics, Inc. Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction
JP5647788B2 (ja) * 2006-10-11 2015-01-07 トルマー セラピューティクス， インコーポレイテッド． 超臨界流体抽出による低バースト特性の生分解性ポリエステルの調製
JP5566885B2 (ja) * 2007-08-01 2014-08-06 エシコン・インコーポレイテッド コラーゲン関連ペプチド及びその使用
US20100151033A1 (en) 2008-12-15 2010-06-17 Novartis Ag Octreotide depot formulation with constantly high exposure levels
RU2491961C2 (ru) * 2009-03-10 2013-09-10 Медприн Редженератив Медикал Текнолоджис Ко., Лтд. Искусственная твердая мозговая оболочка и способ ее производства
JP5555928B2 (ja) * 2009-08-28 2014-07-23 日本バイリーン株式会社 酵素含有ナノファイバーの製造方法、酵素含有ナノファイバー、この酵素含有ナノファイバーを含む不織布及びこの不織布を用いた反応装置
WO2011138974A1 (ja) * 2010-05-07 2011-11-10 帝人株式会社 生体糊用補強材及びその製造方法
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Also Published As

Publication number Publication date
ES2746300T3 (es) 2020-03-05
JP5746430B2 (ja) 2015-07-08
RU2014150498A (ru) 2016-07-10
CN104284673B (zh) 2018-02-13
TW201350147A (zh) 2013-12-16
BR112014028443A8 (pt) 2018-02-06
KR102037555B1 (ko) 2019-10-28
EP2851085B1 (en) 2019-06-26
EP2851085A1 (en) 2015-03-25
HK1204947A1 (en) 2015-12-11
AU2013261308A1 (en) 2014-12-04
JPWO2013172468A1 (ja) 2016-01-12
CN104284673A (zh) 2015-01-14
CA2873602C (en) 2022-08-16
AU2013261308B2 (en) 2018-02-08
TWI636799B (zh) 2018-10-01
US10071061B2 (en) 2018-09-11
RU2695522C2 (ru) 2019-07-23
KR20150023253A (ko) 2015-03-05
BR112014028443A2 (pt) 2017-06-27
DK2851085T3 (da) 2019-09-09
MX2014013818A (es) 2015-05-11
EP2851085A4 (en) 2015-04-15
BR112014028443B1 (pt) 2021-01-19
US20150125511A1 (en) 2015-05-07
IN2014DN09621A (es) 2015-07-31
PT2851085T (pt) 2019-10-11
WO2013172468A1 (ja) 2013-11-21
CA2873602A1 (en) 2013-11-21
PL2851085T3 (pl) 2019-12-31

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