IN2014DN09621A - - Google Patents

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Publication number
IN2014DN09621A
IN2014DN09621A IN9621DEN2014A IN2014DN09621A IN 2014DN09621 A IN2014DN09621 A IN 2014DN09621A IN 9621DEN2014 A IN9621DEN2014 A IN 9621DEN2014A IN 2014DN09621 A IN2014DN09621 A IN 2014DN09621A
Authority
IN
India
Prior art keywords
protein
sterilized
radiation
activity
function
Prior art date
Application number
Inventor
Yukako Kageyama
Kentaro Fujinaga
Ayuko Yamaguchi
Susumu Honda
Makoto Satake
Hiroaki Kaneko
Ayumi Ishiwari
Original Assignee
Teijin Ltd
Teijin Pharma Ltd
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd, Teijin Pharma Ltd, Chemo Sero Therapeut Res Inst filed Critical Teijin Ltd
Publication of IN2014DN09621A publication Critical patent/IN2014DN09621A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/363—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01021—Beta-glucosidase (3.2.1.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Abstract

A sterilized composition sterilized by radiation and containing a protein and an aliphatic polyester containing said protein. This sterilized composition retains the structure and function (activity) of the protein.
IN9621DEN2014 2012-05-14 2013-05-13 IN2014DN09621A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2012110765 2012-05-14
JP2012110390 2012-05-14
JP2013040593 2013-03-01
PCT/JP2013/063868 WO2013172468A1 (en) 2012-05-14 2013-05-13 Sterilized composition

Publications (1)

Publication Number Publication Date
IN2014DN09621A true IN2014DN09621A (en) 2015-07-31

Family

ID=49583866

Family Applications (1)

Application Number Title Priority Date Filing Date
IN9621DEN2014 IN2014DN09621A (en) 2012-05-14 2013-05-13

Country Status (18)

Country Link
US (1) US10071061B2 (en)
EP (1) EP2851085B1 (en)
JP (1) JP5746430B2 (en)
KR (1) KR102037555B1 (en)
CN (1) CN104284673B (en)
AU (1) AU2013261308B2 (en)
BR (1) BR112014028443B1 (en)
CA (1) CA2873602C (en)
DK (1) DK2851085T3 (en)
ES (1) ES2746300T3 (en)
HK (1) HK1204947A1 (en)
IN (1) IN2014DN09621A (en)
MX (1) MX356545B (en)
PL (1) PL2851085T3 (en)
PT (1) PT2851085T (en)
RU (1) RU2695522C2 (en)
TW (1) TWI636799B (en)
WO (1) WO2013172468A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX357254B (en) * 2012-05-14 2018-07-03 Teijin Pharma Ltd Sheet molding and hemostatic material.
NZ726323A (en) 2014-04-30 2020-02-28 Matoke Holdings Ltd Antimicrobial compositions
CA2975197A1 (en) * 2015-02-03 2016-08-11 Matoke Holdings Limited Antimicrobial fibers and compositions
GB201716986D0 (en) 2017-10-16 2017-11-29 Matoke Holdings Ltd Antimicrobial compositions
KR20210132054A (en) 2019-01-31 2021-11-03 셀 메디신 가부시키가이샤 Inorganic salt protein complex medical device

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2209937B (en) 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
JPH0622570B2 (en) 1989-01-31 1994-03-30 多木化学株式会社 Biomaterial
CH679207A5 (en) 1989-07-28 1992-01-15 Debiopharm Sa
US5225205A (en) 1989-07-28 1993-07-06 Debiopharm S.A. Pharmaceutical composition in the form of microparticles
US5439688A (en) 1989-07-28 1995-08-08 Debio Recherche Pharmaceutique S.A. Process for preparing a pharmaceutical composition
CA2033046C (en) 1990-01-12 1999-08-03 Lowell Saferstein Process for preparing a neutralized oxidized cellulose product and its method of use
JP3351525B2 (en) 1991-06-21 2002-11-25 ジェネティックス・インスティテュート・インコーポレイテッド Osteogenic protein pharmaceutical formulation
CH683149A5 (en) 1991-07-22 1994-01-31 Debio Rech Pharma Sa Process for the preparation of microspheres of a biodegradable polymeric material.
GB9206509D0 (en) 1992-03-25 1992-05-06 Jevco Ltd Heteromorphic sponges containing active agents
US5730933A (en) * 1996-04-16 1998-03-24 Depuy Orthopaedics, Inc. Radiation sterilization of biologically active compounds
US5945128A (en) 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
GB2344519B (en) * 1998-12-07 2004-05-19 Johnson & Johnson Medical Ltd Sterile therapeutic compositions
WO2008045516A1 (en) 2006-10-11 2008-04-17 Qlt Usa, Inc. Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction
US8076448B2 (en) 2006-10-11 2011-12-13 Tolmar Therapeutics, Inc. Preparation of biodegradable polyesters with low-burst properties by supercritical fluid extraction
CA2695288A1 (en) * 2007-08-01 2009-02-05 Ethicon, Inc. Collagen-related peptides and uses thereof
US20100151033A1 (en) 2008-12-15 2010-06-17 Novartis Ag Octreotide depot formulation with constantly high exposure levels
MX345863B (en) * 2009-03-10 2017-02-20 Medprin Regenerative Medical Tech Co Ltd Artificial dura mater and manufacturing method thereof.
JP5555928B2 (en) 2009-08-28 2014-07-23 日本バイリーン株式会社 Method for producing enzyme-containing nanofiber, enzyme-containing nanofiber, nonwoven fabric containing this enzyme-containing nanofiber, and reaction apparatus using this nonwoven fabric
JP5479584B2 (en) * 2010-05-07 2014-04-23 帝人株式会社 Reinforcing material for biological glue and method for producing the same
US8273369B2 (en) 2010-05-17 2012-09-25 Ethicon, Inc. Reinforced absorbable synthetic matrix for hemostatic applications
CN103037847B (en) * 2010-06-01 2016-01-20 巴克斯特国际公司 For the preparation of the method for dry, stable hemostatic composition
JP5792442B2 (en) * 2010-09-01 2015-10-14 帝人株式会社 Fiber structure containing cell-specific peptide

Also Published As

Publication number Publication date
KR102037555B1 (en) 2019-10-28
ES2746300T3 (en) 2020-03-05
RU2695522C2 (en) 2019-07-23
RU2014150498A (en) 2016-07-10
BR112014028443A8 (en) 2018-02-06
AU2013261308B2 (en) 2018-02-08
EP2851085B1 (en) 2019-06-26
US20150125511A1 (en) 2015-05-07
EP2851085A1 (en) 2015-03-25
DK2851085T3 (en) 2019-09-09
MX356545B (en) 2018-06-01
CN104284673B (en) 2018-02-13
CA2873602C (en) 2022-08-16
TW201350147A (en) 2013-12-16
CN104284673A (en) 2015-01-14
WO2013172468A1 (en) 2013-11-21
PL2851085T3 (en) 2019-12-31
KR20150023253A (en) 2015-03-05
US10071061B2 (en) 2018-09-11
BR112014028443A2 (en) 2017-06-27
JPWO2013172468A1 (en) 2016-01-12
TWI636799B (en) 2018-10-01
JP5746430B2 (en) 2015-07-08
HK1204947A1 (en) 2015-12-11
CA2873602A1 (en) 2013-11-21
EP2851085A4 (en) 2015-04-15
AU2013261308A1 (en) 2014-12-04
PT2851085T (en) 2019-10-11
BR112014028443B1 (en) 2021-01-19
MX2014013818A (en) 2015-05-11

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