MX355177B - Composicion farmaceutica de avidina oxidada adecuada para inhalacion. - Google Patents
Composicion farmaceutica de avidina oxidada adecuada para inhalacion.Info
- Publication number
- MX355177B MX355177B MX2014001176A MX2014001176A MX355177B MX 355177 B MX355177 B MX 355177B MX 2014001176 A MX2014001176 A MX 2014001176A MX 2014001176 A MX2014001176 A MX 2014001176A MX 355177 B MX355177 B MX 355177B
- Authority
- MX
- Mexico
- Prior art keywords
- inhalation
- oxidised
- pharmaceutical composition
- avidin
- avidin suitable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/66—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells
- A61K47/665—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid the modifying agent being a pre-targeting system involving a peptide or protein for targeting specific cells the pre-targeting system, clearing therapy or rescue therapy involving biotin-(strept) avidin systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/041—Heterocyclic compounds
- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Marine Sciences & Fisheries (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Otolaryngology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a una avidina oxidada para usarse como un agente de acondicionamiento de pulmón administrable por inhalación, para el tratamiento de enfermedades de cáncer de pulmón, enfermedades de inflamación pulmonar seleccionadas del grupo formado por EPOC, asma, alveolitis pulmonar y la fibrosis quística y deficiencia de alfa-1-antitripsina.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11006338 | 2011-08-02 | ||
PCT/EP2012/064576 WO2013017494A1 (en) | 2011-08-02 | 2012-07-25 | Pharmaceutical composition of oxidised avidin suitable for inhalation |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014001176A MX2014001176A (es) | 2014-07-14 |
MX355177B true MX355177B (es) | 2018-04-09 |
Family
ID=46581966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014001176A MX355177B (es) | 2011-08-02 | 2012-07-25 | Composicion farmaceutica de avidina oxidada adecuada para inhalacion. |
Country Status (18)
Country | Link |
---|---|
US (1) | US9872831B2 (es) |
EP (1) | EP2739314B1 (es) |
JP (1) | JP6019118B2 (es) |
KR (1) | KR101966630B1 (es) |
CN (1) | CN103717239B (es) |
AU (1) | AU2012292229B2 (es) |
BR (1) | BR112014002593B1 (es) |
CA (1) | CA2842276C (es) |
DK (1) | DK2739314T3 (es) |
EA (1) | EA026453B1 (es) |
ES (1) | ES2729549T3 (es) |
IL (1) | IL230597A0 (es) |
MX (1) | MX355177B (es) |
PL (1) | PL2739314T3 (es) |
PT (1) | PT2739314T (es) |
UA (1) | UA114482C2 (es) |
WO (1) | WO2013017494A1 (es) |
ZA (1) | ZA201401921B (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2941243A4 (en) | 2013-01-04 | 2016-09-14 | Massachusetts Inst Technology | SURFACE BINDING IN THE ADMINISTRATION OF A MEDICAMENT ON NANOPARTICLE BASE IN A TISSUE |
US20200179530A1 (en) * | 2016-05-19 | 2020-06-11 | University Of Miami | Targeted delivery of therapeutic agents and imaging reagents to pancreatic cancer cells |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5384128A (en) * | 1993-03-02 | 1995-01-24 | University Of Alabama Research Foundation | Method of and compounds for treatment for cystic fibrosis |
WO1995003034A1 (en) | 1993-07-19 | 1995-02-02 | Amgen Inc. | Stabilization of aerosolized proteins |
ATE296115T1 (de) * | 1997-02-20 | 2005-06-15 | David S Dime | Ortsspezifische arzneimittel verabreichung |
JP2002541213A (ja) * | 1999-04-13 | 2002-12-03 | インヘール セラピューティック システムズ, インコーポレイテッド | 不妊症の処置のための乾燥粉末処方物の肺投与 |
US7001994B2 (en) * | 2001-01-18 | 2006-02-21 | Genzyme Corporation | Methods for introducing mannose 6-phosphate and other oligosaccharides onto glycoproteins |
ITRM20010079A1 (it) | 2001-02-16 | 2002-08-16 | Sigma Tau Ind Farmaceuti | Amminoderivati della biotina e loro coniugati con chelanti macrociclici. |
ITRM20030196A1 (it) * | 2003-04-24 | 2004-10-25 | Sigma Tau Ind Farmaceuti | Uso di reagenti per la preparazione di un medicamento |
KR20070100735A (ko) * | 2004-12-17 | 2007-10-11 | 씨아이피엘에이 엘티디. | 약학적 화합물 및 조성물 |
GB0602778D0 (en) * | 2006-02-10 | 2006-03-22 | Glaxo Group Ltd | Novel compound |
ES2625815T3 (es) * | 2007-08-02 | 2017-07-20 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Avidina oxidada con alto tiempo de residencia en los tejidos tratados |
EP2106806A1 (en) * | 2008-03-31 | 2009-10-07 | Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung e.V. | Nanoparticles for targeted delivery of active agents to the lung |
TW201031436A (en) * | 2009-02-16 | 2010-09-01 | Univ Nat Taiwan | Pharmaceutical composition for inhalation delivery and fabrication method thereof |
-
2012
- 2012-07-25 PL PL12740137T patent/PL2739314T3/pl unknown
- 2012-07-25 EA EA201490401A patent/EA026453B1/ru not_active IP Right Cessation
- 2012-07-25 UA UAA201402021A patent/UA114482C2/uk unknown
- 2012-07-25 CA CA2842276A patent/CA2842276C/en active Active
- 2012-07-25 BR BR112014002593-2A patent/BR112014002593B1/pt active IP Right Grant
- 2012-07-25 EP EP12740137.0A patent/EP2739314B1/en active Active
- 2012-07-25 DK DK12740137.0T patent/DK2739314T3/da active
- 2012-07-25 WO PCT/EP2012/064576 patent/WO2013017494A1/en active Application Filing
- 2012-07-25 KR KR1020147001707A patent/KR101966630B1/ko active IP Right Grant
- 2012-07-25 CN CN201280037217.9A patent/CN103717239B/zh active Active
- 2012-07-25 US US14/236,445 patent/US9872831B2/en active Active
- 2012-07-25 AU AU2012292229A patent/AU2012292229B2/en active Active
- 2012-07-25 PT PT12740137T patent/PT2739314T/pt unknown
- 2012-07-25 ES ES12740137T patent/ES2729549T3/es active Active
- 2012-07-25 JP JP2014523289A patent/JP6019118B2/ja active Active
- 2012-07-25 MX MX2014001176A patent/MX355177B/es active IP Right Grant
-
2014
- 2014-01-22 IL IL230597A patent/IL230597A0/en active IP Right Grant
- 2014-02-27 ZA ZA2014/01921A patent/ZA201401921B/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL2739314T3 (pl) | 2019-09-30 |
UA114482C2 (uk) | 2017-06-26 |
EP2739314A1 (en) | 2014-06-11 |
CN103717239B (zh) | 2017-08-01 |
EA026453B1 (ru) | 2017-04-28 |
EP2739314B1 (en) | 2019-05-22 |
CN103717239A (zh) | 2014-04-09 |
KR20140047668A (ko) | 2014-04-22 |
AU2012292229B2 (en) | 2017-08-03 |
IL230597A0 (en) | 2014-03-31 |
EA201490401A1 (ru) | 2014-05-30 |
BR112014002593B1 (pt) | 2022-11-29 |
BR112014002593A2 (pt) | 2017-03-01 |
CA2842276C (en) | 2020-11-24 |
ZA201401921B (en) | 2015-05-27 |
JP6019118B2 (ja) | 2016-11-02 |
ES2729549T3 (es) | 2019-11-04 |
CA2842276A1 (en) | 2013-02-07 |
WO2013017494A1 (en) | 2013-02-07 |
PT2739314T (pt) | 2019-06-21 |
US9872831B2 (en) | 2018-01-23 |
MX2014001176A (es) | 2014-07-14 |
KR101966630B1 (ko) | 2019-04-09 |
US20140134106A1 (en) | 2014-05-15 |
NZ620202A (en) | 2016-05-27 |
AU2012292229A1 (en) | 2014-02-13 |
JP2014521675A (ja) | 2014-08-28 |
DK2739314T3 (da) | 2019-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights |
Owner name: ALFASIGMA S.P.A. |
|
FG | Grant or registration |