LV14848A - Farmaceitiska kompozīcija trimetilamīna N-oksīda līmeņa pazemināšanai - Google Patents

Farmaceitiska kompozīcija trimetilamīna N-oksīda līmeņa pazemināšanai

Info

Publication number
LV14848A
LV14848A LVP-12-163A LV120163A LV14848A LV 14848 A LV14848 A LV 14848A LV 120163 A LV120163 A LV 120163A LV 14848 A LV14848 A LV 14848A
Authority
LV
Latvia
Prior art keywords
oxide
pharmaceutical composition
level
trimethylamin
lowering
Prior art date
Application number
LVP-12-163A
Other languages
English (en)
Other versions
LV14848B (lv
Inventor
Ivars KALVIŅŠ
Maija Dambrova
Edgars LIEPIŅŠ
Elīna ŠKAPARE
Osvalds PUGOVIČS
Solveiga Grīnberga
Eduards Sevostjanovs
Original Assignee
Latvijas Organiskās Sintēzes Institūts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Latvijas Organiskās Sintēzes Institūts filed Critical Latvijas Organiskās Sintēzes Institūts
Priority to LVP-12-163A priority Critical patent/LV14848B/lv
Priority to CN201380041723.XA priority patent/CN104619316B/zh
Priority to UAA201413208U priority patent/UA109944U/uk
Priority to PCT/IB2013/059604 priority patent/WO2014064630A1/en
Priority to JP2015538610A priority patent/JP2015536330A/ja
Priority to CA2878190A priority patent/CA2878190A1/en
Priority to EP13826596.2A priority patent/EP2911658A1/en
Priority to EA201500446A priority patent/EA201500446A1/ru
Priority to US14/420,898 priority patent/US20150313862A1/en
Publication of LV14848A publication Critical patent/LV14848A/lv
Publication of LV14848B publication Critical patent/LV14848B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Izgudrojums apraksta 3-(2,2,2-trimetilhidrazīnij)propionāta dihidrāta saturošas farmaceitiskas kompozīcijas pielietošanu trimetilamīna N-oksīda līmeņa pazemināšanai organismā.
LVP-12-163A 2012-10-25 2012-10-25 Farmaceitiska kompozīcija trimetilamīna-N-oksīda līmeņa pazemināšanai LV14848B (lv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
LVP-12-163A LV14848B (lv) 2012-10-25 2012-10-25 Farmaceitiska kompozīcija trimetilamīna-N-oksīda līmeņa pazemināšanai
CN201380041723.XA CN104619316B (zh) 2012-10-25 2013-10-24 用于降低n-氧化三甲胺水平的药物组合物
UAA201413208U UA109944U (uk) 2012-10-25 2013-10-24 Фармацевтична композиція для зниження рівня n-оксиду триметиламіну
PCT/IB2013/059604 WO2014064630A1 (en) 2012-10-25 2013-10-24 Pharmaceutical composition for reducing the trimethylamine n-oxide level
JP2015538610A JP2015536330A (ja) 2012-10-25 2013-10-24 トリメチルアミン−ｎ−オキシドのレベルを下げる医薬組成物
CA2878190A CA2878190A1 (en) 2012-10-25 2013-10-24 Pharmaceutical composition for reducing the trimethylamine n-oxide level
EP13826596.2A EP2911658A1 (en) 2012-10-25 2013-10-24 Pharmaceutical composition for reducing the trimethylamine n-oxide level
EA201500446A EA201500446A1 (ru) 2012-10-25 2013-10-24 Фармацевтическая композиция для снижения уровня n-оксида триметиламина
US14/420,898 US20150313862A1 (en) 2012-10-25 2013-10-24 "Pharmaceutical composition for reducing the trimethylamine N-oxide level"

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LVP-12-163A LV14848B (lv) 2012-10-25 2012-10-25 Farmaceitiska kompozīcija trimetilamīna-N-oksīda līmeņa pazemināšanai

Publications (2)

Publication Number Publication Date
LV14848A true LV14848A (lv) 2014-05-20
LV14848B LV14848B (lv) 2015-06-20

Family

ID=50030345

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-12-163A LV14848B (lv) 2012-10-25 2012-10-25 Farmaceitiska kompozīcija trimetilamīna-N-oksīda līmeņa pazemināšanai

Country Status (9)

Country Link
US (1) US20150313862A1 (lv)
EP (1) EP2911658A1 (lv)
JP (1) JP2015536330A (lv)
CN (1) CN104619316B (lv)
CA (1) CA2878190A1 (lv)
EA (1) EA201500446A1 (lv)
LV (1) LV14848B (lv)
UA (1) UA109944U (lv)
WO (1) WO2014064630A1 (lv)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160089386A1 (en) * 2014-09-26 2016-03-31 The Cleveland Clinic Foundation Treating and preventing disease with tma and tmao lowering agents
JP2020061956A (ja) * 2018-10-16 2020-04-23 日本水産株式会社 血清中ｔｍａｏ低減用組成物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU997646A1 (ru) * 1978-11-27 1983-02-23 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср Кормова добавка
LV11728B (en) * 1995-08-21 1997-08-20 Kalvins Ivars Pharmaceutical composition
LV13280B (en) * 2003-08-04 2005-11-20 Grindeks Publiska As Sustained release salts of 3-(2,2,2-trimethylhydrazinium)propionate, a method of production and pharmaceutical compositions thereof
ATE386014T1 (de) * 2003-08-04 2008-03-15 Grindeks Jsc Meldoniumsalze, verfahren zu deren herstellung und auf ihnen basierende pharmazeutische zusammensetzung
EP1865945A4 (en) * 2005-03-11 2008-05-21 Hong Kong Nitric Oxide Ltd TREATMENT COMBINATION FOR ENDOTHELIAL DISORDERS, ANGINA AND DIABETES
LV13544B (en) * 2005-08-15 2007-05-20 Grindeks As Pharmaceutical composition containing reverse transcriptase inhibitor and meldonium
CN101152171B (zh) * 2007-10-16 2010-06-02 沈阳格林制药有限公司 一种米屈肼注射液的制备方法
LV14274B (lv) * 2009-06-25 2011-03-20 Grindeks, A/S Meldoniju saturošs kombinēts medicīniskais produkts
KR20120050437A (ko) * 2009-06-25 2012-05-18 테트라, 시아 신규한 아세틸살리실산 염들
LV14268B (lv) * 2009-06-25 2011-03-20 Grindeks, A/S Meldonija sukcinātu saturoši medicīniskie produkti
WO2010149654A1 (en) * 2009-06-25 2010-12-29 Grindeks, A Joint Stock Company Pharmaceutical composition of gamma-butyrobetaine or a pharmaceutically acceptable salt and meldonium or a pharmaceutically acceptable salt

Also Published As

Publication number Publication date
US20150313862A1 (en) 2015-11-05
CN104619316B (zh) 2018-04-27
EP2911658A1 (en) 2015-09-02
LV14848B (lv) 2015-06-20
CN104619316A (zh) 2015-05-13
EA201500446A1 (ru) 2016-05-31
WO2014064630A1 (en) 2014-05-01
UA109944U (uk) 2016-09-26
CA2878190A1 (en) 2014-05-01
JP2015536330A (ja) 2015-12-21

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