MX353727B - Tratamiento de sinucleinopatias. - Google Patents

Tratamiento de sinucleinopatias.

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Publication number
MX353727B
MX353727B MX2009012307A MX2009012307A MX353727B MX 353727 B MX353727 B MX 353727B MX 2009012307 A MX2009012307 A MX 2009012307A MX 2009012307 A MX2009012307 A MX 2009012307A MX 353727 B MX353727 B MX 353727B
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MX
Mexico
Prior art keywords
synucleinopathies
treatment
subjects
well
relates generally
Prior art date
Application number
MX2009012307A
Other languages
English (en)
Other versions
MX2009012307A (es
Inventor
Schloss-Macher Michael
Cullen Valerie
Shihabuddin Lamya
H Cheng Seng
Original Assignee
The Brigham And Womens Hospital Inc Star
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40122277&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX353727(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Brigham And Womens Hospital Inc Star filed Critical The Brigham And Womens Hospital Inc Star
Publication of MX2009012307A publication Critical patent/MX2009012307A/es
Publication of MX353727B publication Critical patent/MX353727B/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01045—Glucosylceramidase (3.2.1.45), i.e. beta-glucocerebrosidase
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    • C12Y304/23—Aspartic endopeptidases (3.4.23)
    • C12Y304/23005—Cathepsin D (3.4.23.5)

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Abstract

La presente invención se refiere de manera general a tratar sinucleinopatías en sujetos que no son diagnosticados clínicamente con una enfermedad de almacenamiento lisosomal, así como asociada con método para hacer medicamente y método de clasificación.
MX2009012307A 2007-05-16 2008-05-16 Tratamiento de sinucleinopatias. MX353727B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US93046207P 2007-05-16 2007-05-16
US92955407P 2007-07-03 2007-07-03
PCT/US2008/064017 WO2008144591A2 (en) 2007-05-16 2008-05-16 Treatment of synucleinopathies

Publications (2)

Publication Number Publication Date
MX2009012307A MX2009012307A (es) 2010-02-10
MX353727B true MX353727B (es) 2017-12-18

Family

ID=40122277

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012307A MX353727B (es) 2007-05-16 2008-05-16 Tratamiento de sinucleinopatias.

Country Status (18)

Country Link
US (4) US8454954B2 (es)
EP (2) EP2154969B1 (es)
JP (4) JP5291093B2 (es)
CN (2) CN101754682B (es)
AU (1) AU2008254774B2 (es)
BR (1) BRPI0811265A2 (es)
CA (1) CA2684946C (es)
CY (1) CY1117312T1 (es)
DK (1) DK2154969T3 (es)
ES (1) ES2559859T3 (es)
HK (2) HK1141406A1 (es)
HR (1) HRP20151409T1 (es)
HU (1) HUE027278T2 (es)
MX (1) MX353727B (es)
PL (1) PL2154969T3 (es)
PT (1) PT2154969E (es)
SI (1) SI2154969T1 (es)
WO (1) WO2008144591A2 (es)

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CN112501208A (zh) 2017-10-03 2021-03-16 普利维尔治疗公司 用于溶酶体障碍的基因疗法
CN112481269A (zh) 2017-10-03 2021-03-12 普利维尔治疗公司 用于溶酶体障碍的基因疗法
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KR20220006527A (ko) 2019-04-10 2022-01-17 프리베일 테라퓨틱스, 인크. 리소좀 장애에 대한 유전자 요법
CN114466656A (zh) * 2019-07-24 2022-05-10 康德生物医疗有限公司 在治疗神经变性病症中的模拟肽化合物(r)-2-氨基-n-((s)-1-(((s)-5-氨基-1-(3-苄基-1,2,4-噁二唑-5-基)戊基)氨基)-3-(4-羟基-2,6-二甲苯基)-1-氧代丙-2-基)-5-胍基戊酰胺
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CA2684946A1 (en) 2008-11-27
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