MX353280B - Suministro de farmaco biodegradable para las composiciones hidrofobicas. - Google Patents

Suministro de farmaco biodegradable para las composiciones hidrofobicas.

Info

Publication number
MX353280B
MX353280B MX2014015902A MX2014015902A MX353280B MX 353280 B MX353280 B MX 353280B MX 2014015902 A MX2014015902 A MX 2014015902A MX 2014015902 A MX2014015902 A MX 2014015902A MX 353280 B MX353280 B MX 353280B
Authority
MX
Mexico
Prior art keywords
drug delivery
biodegradable drug
hydrophobic compositions
polyester
polyethylene glycol
Prior art date
Application number
MX2014015902A
Other languages
English (en)
Other versions
MX2014015902A (es
Inventor
Gaudriault Georges
Roberge Christophe
Original Assignee
Medincell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49117888&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX353280(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medincell filed Critical Medincell
Publication of MX2014015902A publication Critical patent/MX2014015902A/es
Publication of MX353280B publication Critical patent/MX353280B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/26Glucagons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen las composiciones de suministro de fármaco biodegradable que comprenden un copolímero tribloque que contiene un poliéster y un polietilenglicol y un copolímero dibloque que contiene un poliéster y un polietilenglicol con extremos protegidos, así como por lo menos un principio farmacéuticamente activo o un principio hidrofóbico activo como acetato de medroxiprogesterona, levonorgestrel, ciclosporina, progesterona o bupivacaína.
MX2014015902A 2012-06-27 2013-06-27 Suministro de farmaco biodegradable para las composiciones hidrofobicas. MX353280B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261665192P 2012-06-27 2012-06-27
PCT/IB2013/001547 WO2014001904A1 (en) 2012-06-27 2013-06-27 Biodegradable drug delivery for hydrophobic compositions

Publications (2)

Publication Number Publication Date
MX2014015902A MX2014015902A (es) 2015-07-17
MX353280B true MX353280B (es) 2018-01-05

Family

ID=49117888

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014015902A MX353280B (es) 2012-06-27 2013-06-27 Suministro de farmaco biodegradable para las composiciones hidrofobicas.

Country Status (24)

Country Link
US (5) US20150150987A1 (es)
EP (1) EP2866837B1 (es)
JP (1) JP6134788B2 (es)
KR (1) KR102189442B1 (es)
CN (1) CN104582733B (es)
AU (1) AU2013282891B2 (es)
BR (1) BR112014031773B1 (es)
CA (1) CA2877083C (es)
CL (1) CL2014003531A1 (es)
CO (1) CO7160098A2 (es)
CR (1) CR20140581A (es)
CU (1) CU24287B1 (es)
EA (1) EA031522B1 (es)
ES (1) ES2938586T3 (es)
HK (1) HK1208374A1 (es)
IL (1) IL236472B (es)
IN (1) IN2014DN11063A (es)
MA (1) MA37809B1 (es)
MX (1) MX353280B (es)
SG (1) SG11201408658PA (es)
TN (1) TN2014000520A1 (es)
UA (1) UA113549C2 (es)
WO (2) WO2014001905A1 (es)
ZA (1) ZA201409291B (es)

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EP3936133A1 (en) 2011-11-23 2022-01-12 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
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CA3042642A1 (en) 2013-08-12 2015-02-19 Pharmaceutical Manufacturing Research Services, Inc. Extruded immediate release abuse deterrent pill
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CA2947767A1 (en) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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WO2016054197A1 (en) * 2014-09-30 2016-04-07 University Of Tennessee Research Foundation In situ gelling form for long-acting drug delivery
US20160106737A1 (en) 2014-10-20 2016-04-21 Pharmaceutical Manufacturing Research Services, Inc. Extended Release Abuse Deterrent Liquid Fill Dosage Form
FR3027522B1 (fr) 2014-10-27 2016-12-09 I Ceram Composition poreuse chargee en principe actif
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
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BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
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TWI795421B (zh) * 2017-07-17 2023-03-11 法商麥迪榭爾公司 用於調節至少一種活性成份之藥物釋放動力學的可生物降解之藥物傳遞之組合物混合物
CN108078911A (zh) * 2017-12-08 2018-05-29 复旦大学 用于动物避孕的热致水凝胶缓释兽药注射剂及其制备方法
CA3110250A1 (en) * 2018-08-22 2020-02-27 Bacainn Therapeutics, Ltd. Cyclosporine compositions and methods of use
GB201900258D0 (en) * 2019-01-08 2019-02-27 Medincell Pharmaceutical composition
AU2020346455A1 (en) * 2019-09-13 2022-03-31 Medincell S.A. Drug delivery formulations
CN111700876A (zh) * 2020-03-12 2020-09-25 上海市肿瘤研究所 一种治疗系统性红斑狼疮的载药递送给药系统及其制备方法
WO2022129417A1 (en) 2020-12-16 2022-06-23 Medincell Methods and compositions for the prophylactic treatment of sars-cov-2 virus (covid-19)
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Also Published As

Publication number Publication date
MA37809A1 (fr) 2017-07-31
SG11201408658PA (en) 2015-02-27
EA031522B1 (ru) 2019-01-31
ZA201409291B (en) 2017-05-31
CL2014003531A1 (es) 2015-08-28
AU2013282891A2 (en) 2015-02-05
CA2877083C (en) 2020-10-06
IL236472A0 (en) 2015-02-26
CN104582733B (zh) 2017-07-04
AU2013282891B2 (en) 2018-04-12
CA2877083A1 (en) 2014-01-02
ES2938586T3 (es) 2023-04-12
US20190160171A1 (en) 2019-05-30
KR102189442B1 (ko) 2020-12-11
KR20150027265A (ko) 2015-03-11
AU2013282891A1 (en) 2015-01-22
WO2014001904A1 (en) 2014-01-03
EA201492172A1 (ru) 2015-09-30
JP6134788B2 (ja) 2017-05-24
MX2014015902A (es) 2015-07-17
US20220354956A1 (en) 2022-11-10
CN104582733A (zh) 2015-04-29
CU24287B1 (es) 2017-12-08
HK1208374A1 (en) 2016-03-04
US20150150987A1 (en) 2015-06-04
TN2014000520A1 (en) 2016-03-30
CR20140581A (es) 2015-02-06
WO2014001905A1 (en) 2014-01-03
CU20140148A7 (es) 2015-03-30
JP2015522001A (ja) 2015-08-03
EP2866837B1 (en) 2022-12-14
CO7160098A2 (es) 2015-01-15
BR112014031773B1 (pt) 2020-10-13
BR112014031773A2 (pt) 2017-06-27
EP2866837A1 (en) 2015-05-06
MA37809B1 (fr) 2018-12-31
UA113549C2 (xx) 2017-02-10
US20200085958A1 (en) 2020-03-19
US20210008216A1 (en) 2021-01-14
IN2014DN11063A (es) 2015-09-25
IL236472B (en) 2020-02-27

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