MX348580B - Sal de un derivado del ácido pirrolidín-3-ilacético y cristales de ésta. - Google Patents
Sal de un derivado del ácido pirrolidín-3-ilacético y cristales de ésta.Info
- Publication number
- MX348580B MX348580B MX2015010984A MX2015010984A MX348580B MX 348580 B MX348580 B MX 348580B MX 2015010984 A MX2015010984 A MX 2015010984A MX 2015010984 A MX2015010984 A MX 2015010984A MX 348580 B MX348580 B MX 348580B
- Authority
- MX
- Mexico
- Prior art keywords
- crystals
- acetic acid
- pyrrolidin
- salt
- acid derivative
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 2
- OUENRUZPZZFMCA-UHFFFAOYSA-N 2-pyrrolidin-1-ium-3-ylacetate Chemical class OC(=O)CC1CCNC1 OUENRUZPZZFMCA-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000007942 carboxylates Chemical class 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
- C07C59/50—Mandelic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Una sal de un ácido carboxílico orgánico del ácido 2- [(3S,4R)-1-{ [2-cloro-6-(trifluorometil)fenil]metil}-3-{ [1- (ciclohex-1-en-1-ilmetil)piperidin-4-il]carbamoil}-4- metilpirrolidin-3-il]acético y un cristal de esta.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013049619 | 2013-03-12 | ||
| PCT/JP2014/056123 WO2014142056A1 (ja) | 2013-03-12 | 2014-03-10 | ピロリジン－３－イル酢酸誘導体の塩およびその結晶 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015010984A MX2015010984A (es) | 2015-10-26 |
| MX348580B true MX348580B (es) | 2017-06-20 |
Family
ID=51536713
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015010984A MX348580B (es) | 2013-03-12 | 2014-03-10 | Sal de un derivado del ácido pirrolidín-3-ilacético y cristales de ésta. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9550732B2 (es) |
| EP (1) | EP2975035B1 (es) |
| JP (1) | JP5872105B2 (es) |
| KR (1) | KR20150129698A (es) |
| CN (1) | CN105073727B (es) |
| AU (1) | AU2014231863B2 (es) |
| BR (1) | BR112015021848A2 (es) |
| CA (1) | CA2900926A1 (es) |
| ES (1) | ES2642805T3 (es) |
| IL (1) | IL240795A0 (es) |
| MX (1) | MX348580B (es) |
| RU (1) | RU2640047C2 (es) |
| WO (1) | WO2014142056A1 (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110198210B (zh) * | 2012-07-27 | 2021-10-26 | 华为技术有限公司 | 用于多点通信的系统和方法 |
| US10412611B2 (en) * | 2015-04-06 | 2019-09-10 | Lg Electronics Inc. | Mobility management for high-speed mobile user equipment |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4263391B2 (ja) | 2001-03-19 | 2009-05-13 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 抗ｃｘ３ｃｒ１抗体、抗フラクタルカイン抗体及びフラクタルカインの利用 |
| WO2003037271A2 (en) * | 2001-10-30 | 2003-05-08 | Millennium Pharmaceuticals,Inc. | Compounds, pharmaceutical compositions and methods of use therefor |
| SE0302666D0 (sv) * | 2003-10-07 | 2003-10-07 | Astrazeneca Ab | Novel Compounds |
| JP2007507494A (ja) * | 2003-10-07 | 2007-03-29 | アストラゼネカ・アクチエボラーグ | ケモカイン受容体アンタゴニストとりわけＣＸ３ＣＲ１として有用な新規な２−置換４−アミノ−チアゾロ［４，５−ｄ］ピリミジン |
| UA90707C2 (en) | 2005-04-06 | 2010-05-25 | Астразенека Аб | Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives |
| AR053347A1 (es) * | 2005-04-06 | 2007-05-02 | Astrazeneca Ab | Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos |
| MX2009003003A (es) | 2006-09-29 | 2009-04-01 | Astrazeneca Ab | Nuevos derivados de [1,3]tiazolo [4,5-d]pirimidin-2-(3h)-amina 5,7-disustituidos y su uso en terapia. |
| TW200820973A (en) | 2006-09-29 | 2008-05-16 | Astrazeneca Ab | Novel compounds 480 |
| CL2007002958A1 (es) * | 2006-10-12 | 2008-05-09 | Epix Delaware Inc | Compuestos derivados de heteroaril-carboxamida, antagonistas del receptor de quimioquina; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades tales como rechazo de transplante de organos, artritis reumatoidea, lupus, entr |
| KR101581829B1 (ko) * | 2008-03-07 | 2015-12-31 | 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 | 1-벤질-3-하이드록시메틸인다졸 유도체들 및 ｍｃｐ-1 및 ｃｘ3ｃｒ1의 발현을 기초로 한 질환들의 치료에서 이의 용도 |
| AR071036A1 (es) | 2008-03-26 | 2010-05-19 | Astrazeneca Ab | Derivados 5, 7-disustituidos de [1, 3]tiazolo[4, 5-d]pirimidin-2 (3h)-ona, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por el receptor cx3cr1. |
| US8476301B2 (en) * | 2011-09-13 | 2013-07-02 | Eisai R&D Management Co., Ltd. | Pyrrolidin-3-ylacetic acid derivative |
| JO3082B1 (ar) * | 2011-09-13 | 2017-03-15 | Eisai R&D Man Co Ltd | مشتق بيروليدين-3- يل حمض خليك |
-
2014
- 2014-03-10 US US14/768,520 patent/US9550732B2/en not_active Expired - Fee Related
- 2014-03-10 AU AU2014231863A patent/AU2014231863B2/en not_active Ceased
- 2014-03-10 ES ES14762496.9T patent/ES2642805T3/es active Active
- 2014-03-10 WO PCT/JP2014/056123 patent/WO2014142056A1/ja active Application Filing
- 2014-03-10 MX MX2015010984A patent/MX348580B/es active IP Right Grant
- 2014-03-10 CA CA2900926A patent/CA2900926A1/en not_active Abandoned
- 2014-03-10 BR BR112015021848A patent/BR112015021848A2/pt not_active Application Discontinuation
- 2014-03-10 RU RU2015138393A patent/RU2640047C2/ru not_active IP Right Cessation
- 2014-03-10 CN CN201480012170.XA patent/CN105073727B/zh not_active Expired - Fee Related
- 2014-03-10 KR KR1020157023870A patent/KR20150129698A/ko not_active Application Discontinuation
- 2014-03-10 JP JP2015505455A patent/JP5872105B2/ja not_active Expired - Fee Related
- 2014-03-10 EP EP14762496.9A patent/EP2975035B1/en not_active Not-in-force
-
2015
- 2015-08-24 IL IL240795A patent/IL240795A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2015010984A (es) | 2015-10-26 |
| BR112015021848A2 (pt) | 2020-02-11 |
| AU2014231863B2 (en) | 2017-07-27 |
| RU2015138393A (ru) | 2017-04-18 |
| CN105073727A (zh) | 2015-11-18 |
| US9550732B2 (en) | 2017-01-24 |
| JP5872105B2 (ja) | 2016-03-01 |
| CN105073727B (zh) | 2017-02-22 |
| WO2014142056A1 (ja) | 2014-09-18 |
| CA2900926A1 (en) | 2014-09-18 |
| KR20150129698A (ko) | 2015-11-20 |
| EP2975035A1 (en) | 2016-01-20 |
| IL240795A0 (en) | 2015-10-29 |
| ES2642805T3 (es) | 2017-11-20 |
| EP2975035A4 (en) | 2016-09-07 |
| US20160002165A1 (en) | 2016-01-07 |
| AU2014231863A1 (en) | 2015-08-27 |
| JPWO2014142056A1 (ja) | 2017-02-16 |
| EP2975035B1 (en) | 2017-08-02 |
| RU2640047C2 (ru) | 2017-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |