MX346244B - Composiciones de vancomicina en polvo seco y metodos asociados. - Google Patents
Composiciones de vancomicina en polvo seco y metodos asociados.Info
- Publication number
- MX346244B MX346244B MX2013013503A MX2013013503A MX346244B MX 346244 B MX346244 B MX 346244B MX 2013013503 A MX2013013503 A MX 2013013503A MX 2013013503 A MX2013013503 A MX 2013013503A MX 346244 B MX346244 B MX 346244B
- Authority
- MX
- Mexico
- Prior art keywords
- subject
- dry powder
- bacterial infection
- compositions
- associated methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 108010059993 Vancomycin Proteins 0.000 title abstract 2
- 239000000843 powder Substances 0.000 title abstract 2
- MYPYJXKWCTUITO-LYRMYLQWSA-N vancomycin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C2C=C3C=C1OC1=CC=C(C=C1Cl)[C@@H](O)[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@H]3C(=O)N[C@H]1C(=O)N[C@H](C(N[C@@H](C3=CC(O)=CC(O)=C3C=3C(O)=CC=C1C=3)C(O)=O)=O)[C@H](O)C1=CC=C(C(=C1)Cl)O2)=O)NC(=O)[C@@H](CC(C)C)NC)[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1 MYPYJXKWCTUITO-LYRMYLQWSA-N 0.000 title abstract 2
- 229960003165 vancomycin Drugs 0.000 title abstract 2
- MYPYJXKWCTUITO-UHFFFAOYSA-N vancomycin Natural products O1C(C(=C2)Cl)=CC=C2C(O)C(C(NC(C2=CC(O)=CC(O)=C2C=2C(O)=CC=C3C=2)C(O)=O)=O)NC(=O)C3NC(=O)C2NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(CC(C)C)NC)C(O)C(C=C3Cl)=CC=C3OC3=CC2=CC1=C3OC1OC(CO)C(O)C(O)C1OC1CC(C)(N)C(O)C(C)O1 MYPYJXKWCTUITO-UHFFFAOYSA-N 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 3
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 1
- 208000019693 Lung disease Diseases 0.000 abstract 1
- 206010035664 Pneumonia Diseases 0.000 abstract 1
- 201000009267 bronchiectasis Diseases 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Otolaryngology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487971P | 2011-05-19 | 2011-05-19 | |
| PCT/US2012/038775 WO2012159103A1 (en) | 2011-05-19 | 2012-05-21 | Dry powder vancomycin compositions and associated methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2013013503A MX2013013503A (es) | 2014-05-12 |
| MX346244B true MX346244B (es) | 2017-03-13 |
Family
ID=47177374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2013013503A MX346244B (es) | 2011-05-19 | 2012-05-21 | Composiciones de vancomicina en polvo seco y metodos asociados. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP2709646A4 (enExample) |
| JP (1) | JP6012716B2 (enExample) |
| KR (1) | KR101763195B1 (enExample) |
| CN (1) | CN103717231B (enExample) |
| AU (1) | AU2012254999B2 (enExample) |
| BR (1) | BR112013029803B1 (enExample) |
| CA (2) | CA2836643C (enExample) |
| IL (1) | IL229506B (enExample) |
| MX (1) | MX346244B (enExample) |
| SG (1) | SG195038A1 (enExample) |
| WO (1) | WO2012159103A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3067047B1 (en) | 2005-12-08 | 2022-04-20 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections |
| US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
| EP3581186A1 (en) | 2012-11-29 | 2019-12-18 | Insmed Incorporated | Stabilized vancomycin formulations |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| CN104043104B (zh) * | 2013-03-15 | 2018-07-10 | 浙江创新生物有限公司 | 含盐酸万古霉素的喷雾干粉及其工业化制备方法 |
| US9925184B2 (en) * | 2013-10-11 | 2018-03-27 | Pulmokine, Inc. | Spray-dry formulations |
| AU2015222051A1 (en) * | 2014-02-28 | 2016-10-13 | Algipharma As | Use of alginate oligomers in the treatment of cystic fibrosis and other conditions associated with defective CFTR ion channel function |
| US10959946B2 (en) | 2014-03-14 | 2021-03-30 | Azurity Pharmaceuticals, Inc. | Composition and method for vancomycin oral liquid |
| KR20240018675A (ko) | 2014-05-15 | 2024-02-13 | 인스메드 인코포레이티드 | 폐의 비-결핵성 마이코박테리아 감염을 치료하기 위한 방법 |
| AU2015341763B2 (en) * | 2014-11-06 | 2019-01-17 | Hikma Pharmaceuticals Usa Inc. | Glycopeptide compositions |
| WO2016127087A1 (en) | 2015-02-06 | 2016-08-11 | Latitude Pharmaceuticals, Inc. | Aqueous solution formulations of vancomycin |
| GB201609940D0 (en) * | 2016-06-07 | 2016-07-20 | Novabiotics Ltd | Microparticles |
| AU2017348354B2 (en) | 2016-10-27 | 2023-06-15 | Pulmokine, Inc. | Combination therapy for treating pulmonary hypertension |
| CN106963939A (zh) * | 2017-03-22 | 2017-07-21 | 永信药品工业（昆山）股份有限公司 | 盐酸万古霉素药物组合物及其制备方法 |
| EP3634464A4 (en) * | 2017-05-22 | 2021-04-07 | Insmed Incorporated | COMPOUNDS DERIVED FROM GLYCOPEPTIDES AND THEIR USES |
| WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
| US20200115412A1 (en) * | 2018-10-15 | 2020-04-16 | Savara Inc. | Separation of vancomycin and its degradation products |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT396333B (de) | 1982-10-08 | 1993-08-25 | Glaxo Group Ltd | Vorrichtung zur verabreichung von medikamenten an patienten, einrichtung mit mehreren solchen vorrichtungen und traeger mit medikamentbehaeltern hiefuer |
| US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
| GR861995B (en) | 1985-07-30 | 1986-11-04 | Glaxo Group Ltd | Devices for administering medicaments to patients |
| JPH03193735A (ja) * | 1989-12-22 | 1991-08-23 | Shionogi & Co Ltd | グリコペプチド系抗生物質の安定化組成物 |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| JP4142149B2 (ja) * | 1997-07-10 | 2008-08-27 | 明治製菓株式会社 | バンコマイシンの凍結乾燥製剤 |
| US6586008B1 (en) * | 1999-08-25 | 2003-07-01 | Advanced Inhalation Research, Inc. | Use of simple amino acids to form porous particles during spray drying |
| DE60025019T2 (de) * | 1999-10-29 | 2006-08-24 | Nektar Therapeutics, San Carlos | Trockenpulverzusammensetzungen mit verbesserter dispersivität |
| JP4837892B2 (ja) * | 2001-11-01 | 2011-12-14 | ネクター セラピューティクス | 粉末バッチを製造する方法 |
| DE10358387A1 (de) * | 2003-12-13 | 2005-07-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulver enthaltend niedermolekulares Dextran und Verfahren zu deren Herstellung |
| FR2872044B1 (fr) * | 2004-06-28 | 2007-06-29 | Flamel Technologies Sa | Formulation pharmaceutique a base d'antibiotique sous forme microcapsulaire |
| EP2050437A1 (en) * | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
| HUE038428T2 (hu) * | 2008-10-07 | 2018-10-29 | Horizon Orphan Llc | Aeroszol fluorokinolon készítmények javított farmakokinetika érdekében |
| JP2012522009A (ja) * | 2009-03-26 | 2012-09-20 | パルマトリックス，インコーポレイテッド | 肺炎および人工呼吸器関連気管気管支炎を治療および予防するための方法 |
| ES2625260T5 (es) * | 2009-03-26 | 2020-07-29 | Pulmatrix Operating Co Inc | Formulaciones de polvo seco y métodos para el tratamiento de enfermedades pulmonares |
-
2012
- 2012-05-21 BR BR112013029803-0A patent/BR112013029803B1/pt not_active IP Right Cessation
- 2012-05-21 CA CA2836643A patent/CA2836643C/en not_active Expired - Fee Related
- 2012-05-21 MX MX2013013503A patent/MX346244B/es active IP Right Grant
- 2012-05-21 JP JP2014511611A patent/JP6012716B2/ja not_active Expired - Fee Related
- 2012-05-21 CN CN201280035537.0A patent/CN103717231B/zh not_active Expired - Fee Related
- 2012-05-21 SG SG2013085394A patent/SG195038A1/en unknown
- 2012-05-21 CA CA2981038A patent/CA2981038C/en not_active Expired - Fee Related
- 2012-05-21 EP EP12785744.9A patent/EP2709646A4/en not_active Withdrawn
- 2012-05-21 WO PCT/US2012/038775 patent/WO2012159103A1/en not_active Ceased
- 2012-05-21 AU AU2012254999A patent/AU2012254999B2/en not_active Ceased
- 2012-05-21 KR KR1020137033895A patent/KR101763195B1/ko not_active Expired - Fee Related
-
2013
- 2013-11-19 IL IL229506A patent/IL229506B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN103717231A (zh) | 2014-04-09 |
| KR101763195B1 (ko) | 2017-07-31 |
| NZ618002A (en) | 2015-03-27 |
| BR112013029803A2 (pt) | 2017-01-17 |
| AU2012254999B2 (en) | 2016-02-11 |
| MX2013013503A (es) | 2014-05-12 |
| BR112013029803B1 (pt) | 2021-07-13 |
| WO2012159103A1 (en) | 2012-11-22 |
| CN103717231B (zh) | 2016-08-17 |
| KR20140032450A (ko) | 2014-03-14 |
| EP2709646A1 (en) | 2014-03-26 |
| IL229506A0 (en) | 2014-01-30 |
| CA2836643C (en) | 2017-11-14 |
| JP2014515356A (ja) | 2014-06-30 |
| SG195038A1 (en) | 2013-12-30 |
| CA2981038C (en) | 2018-09-25 |
| CA2836643A1 (en) | 2012-11-22 |
| JP6012716B2 (ja) | 2016-10-25 |
| IL229506B (en) | 2019-07-31 |
| CA2981038A1 (en) | 2012-11-22 |
| EP2709646A4 (en) | 2015-05-13 |
| NZ704819A (en) | 2016-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |