MX343699B - Construcción de expresión de adn. - Google Patents

Construcción de expresión de adn.

Info

Publication number
MX343699B
MX343699B MX2013007285A MX2013007285A MX343699B MX 343699 B MX343699 B MX 343699B MX 2013007285 A MX2013007285 A MX 2013007285A MX 2013007285 A MX2013007285 A MX 2013007285A MX 343699 B MX343699 B MX 343699B
Authority
MX
Mexico
Prior art keywords
construct
gene expression
expression construct
dna
dna expression
Prior art date
Application number
MX2013007285A
Other languages
English (en)
Other versions
MX2013007285A (es
Inventor
Schroff Matthias
Kleuss Christiane
Kapp Kerstin
Original Assignee
Mologen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598917&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX343699(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mologen Ag filed Critical Mologen Ag
Publication of MX2013007285A publication Critical patent/MX2013007285A/es
Publication of MX343699B publication Critical patent/MX343699B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/24—Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication

Abstract

La presente invención se refiere a una construcción de ADN para expresión génica, en la que la construcción es una doble hélice de ADN lineal y de cadena abierta que comprende una secuencia promotora, una secuencia codificante y una señal de terminación, en la que la construcción comprende al menos un nucleótido de ADN L y en la que solamente dentro de los últimos cinco nucleótidos en el extremo 5´y/o 3´al menos un nucleótido es de ADN L.
MX2013007285A 2010-12-23 2011-12-23 Construcción de expresión de adn. MX343699B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1021873.3A GB201021873D0 (en) 2010-12-23 2010-12-23 DNA expression construct
PCT/EP2011/073984 WO2012085282A1 (en) 2010-12-23 2011-12-23 Dna expression construct

Publications (2)

Publication Number Publication Date
MX2013007285A MX2013007285A (es) 2013-09-26
MX343699B true MX343699B (es) 2016-11-16

Family

ID=43598917

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2013007285A MX343699B (es) 2010-12-23 2011-12-23 Construcción de expresión de adn.

Country Status (20)

Country Link
US (1) US20130287814A1 (es)
EP (1) EP2655620B1 (es)
JP (2) JP6377349B2 (es)
KR (1) KR101517365B1 (es)
CN (1) CN103370413B (es)
AU (1) AU2011347086B2 (es)
BR (1) BR112013015819A2 (es)
CA (1) CA2822367A1 (es)
DK (1) DK2655620T3 (es)
ES (1) ES2549192T3 (es)
GB (1) GB201021873D0 (es)
HK (1) HK1188608A1 (es)
IL (1) IL227104A (es)
MX (1) MX343699B (es)
PL (1) PL2655620T3 (es)
PT (1) PT2655620E (es)
RU (1) RU2604186C2 (es)
SG (1) SG191327A1 (es)
WO (1) WO2012085282A1 (es)
ZA (1) ZA201304998B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201021873D0 (en) * 2010-12-23 2011-02-02 Mologen Ag DNA expression construct
TR201908550T4 (tr) 2014-06-04 2019-07-22 Exicure Inc Profilaktik veya terapötik uygulamalar için lipozomal sferik nükleik asitler tarafından immün modülatörlerin çok değerlikli teslimi.
US11213593B2 (en) 2014-11-21 2022-01-04 Northwestern University Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
LU92821B1 (en) 2015-09-09 2017-03-20 Mologen Ag Combination comprising immunostimulatory oligonucleotides
GB2542425A (en) * 2015-09-21 2017-03-22 Mologen Ag Means for the treatment of HIV
WO2018039629A2 (en) 2016-08-25 2018-03-01 Northwestern University Micellar spherical nucleic acids from thermoresponsive, traceless templates
US11433131B2 (en) 2017-05-11 2022-09-06 Northwestern University Adoptive cell therapy using spherical nucleic acids (SNAs)
EP3854419A1 (en) * 2020-01-24 2021-07-28 Univerzita Karlova, Lekarska fakulta v Plzni Dna conjugate and method of transformation of genes into cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2138553C1 (ru) * 1991-09-30 1999-09-27 Берингер Ингельгейм Интернациональ ГмбХ Трансфекционная композиция для высших эукариотных клеток, комплекс нуклеиновой кислоты, пригодный в качестве компонента трансфекционной композиции, конъюгат, пригодный в качестве компонента трансфекционной композиции, эндосомолитический пептид, пригодный в качестве компонента трансфекционной композиции
TW480282B (en) * 1996-04-24 2002-03-21 Ren Wen Corp Recombinant eucaryotic vector containing allergen gene and use of preventing and treating allergic disease thereof
DE19648625A1 (de) * 1996-11-13 1998-05-14 Soft Gene Gmbh Mikroprojektil für das Einbringen von Substanzen in Zellen durch ballistischen Transfer
AU2002324909A1 (en) * 2001-09-07 2003-03-24 Baylor College Of Medicine Linear dna fragments for gene expression
EP1530641B1 (de) * 2002-07-19 2007-01-24 Mologen AG Dna-expressionskonstrukt zur multiplen genexpression
DE602004031982D1 (de) * 2004-06-23 2011-05-05 Usv Ltd Chimeres, von den placenta- und hypophysenisoformen abgeleitetes humanes wachstumshormon und verfahren zur gewinnung der chimere
WO2009035554A2 (en) * 2007-09-07 2009-03-19 University Of Florida Research Foundation, Inc. Superior structure stability and selectivity of hairpin nucleic acid probes with an l-dna stem
GB201021873D0 (en) * 2010-12-23 2011-02-02 Mologen Ag DNA expression construct

Also Published As

Publication number Publication date
AU2011347086A1 (en) 2013-07-25
PT2655620E (pt) 2015-10-26
RU2013132149A (ru) 2015-01-27
GB201021873D0 (en) 2011-02-02
JP6377349B2 (ja) 2018-08-22
EP2655620A1 (en) 2013-10-30
DK2655620T3 (en) 2015-11-09
CA2822367A1 (en) 2012-06-28
CN103370413A (zh) 2013-10-23
ZA201304998B (en) 2014-03-26
BR112013015819A2 (pt) 2018-05-29
MX2013007285A (es) 2013-09-26
AU2011347086B2 (en) 2015-07-16
CN103370413B (zh) 2016-06-01
JP2018007669A (ja) 2018-01-18
KR101517365B1 (ko) 2015-05-06
KR20130107350A (ko) 2013-10-01
US20130287814A1 (en) 2013-10-31
EP2655620B1 (en) 2015-08-12
IL227104A (en) 2017-02-28
HK1188608A1 (en) 2014-05-09
RU2604186C2 (ru) 2016-12-10
SG191327A1 (en) 2013-07-31
ES2549192T3 (es) 2015-10-23
PL2655620T3 (pl) 2016-01-29
WO2012085282A1 (en) 2012-06-28
JP2014508512A (ja) 2014-04-10

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