MX342897B - Dispositivos y metodos para suministrar agentes bioactivos. - Google Patents

Dispositivos y metodos para suministrar agentes bioactivos.

Info

Publication number
MX342897B
MX342897B MX2011011389A MX2011011389A MX342897B MX 342897 B MX342897 B MX 342897B MX 2011011389 A MX2011011389 A MX 2011011389A MX 2011011389 A MX2011011389 A MX 2011011389A MX 342897 B MX342897 B MX 342897B
Authority
MX
Mexico
Prior art keywords
bioactive agent
devices
invention includes
delivery
methods
Prior art date
Application number
MX2011011389A
Other languages
English (en)
Other versions
MX2011011389A (es
Inventor
A Chappa Ralph
G Bach Andrew
Original Assignee
Surmodics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Surmodics Inc filed Critical Surmodics Inc
Publication of MX2011011389A publication Critical patent/MX2011011389A/es
Publication of MX342897B publication Critical patent/MX342897B/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form

Abstract

Las modalidades de la invención incluyen dispositivos que eluyen agentes bioactivos. En una modalidad, la invención incluye un dispositivo que suministra agentes bioactivos, que incluye un sustrato, un polímero hidrofílico dispuesto sobre el sustrato y un agente bioactivo sustancialmente amorfo dispuesto sobre la superficie del polímero hidrofílico. En una modalidad, la invención incluye un método para producir un dispositivo que suministra agentes bioactivos, que incluye depositar un polímero hidrofílico sobre un sustrato para formar una superficie hidrofílica y depositar un agente bioactivo sustancialmente amorfo sobre la superficie hidrofílica. En una modalidad, la invención incluye un catéter que eluye agentes bioactivos, que incluye un eje del catéter y un globo expansible dispuesto sobre el eje del catéter. En la presente se incluyen otras modalidades.
MX2011011389A 2009-04-28 2010-04-28 Dispositivos y metodos para suministrar agentes bioactivos. MX342897B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17346209P 2009-04-28 2009-04-28
PCT/US2010/032741 WO2010129328A2 (en) 2009-04-28 2010-04-28 Devices and methods for delivery of bioactive agents

Publications (2)

Publication Number Publication Date
MX2011011389A MX2011011389A (es) 2011-11-18
MX342897B true MX342897B (es) 2016-10-18

Family

ID=42562122

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011011389A MX342897B (es) 2009-04-28 2010-04-28 Dispositivos y metodos para suministrar agentes bioactivos.

Country Status (8)

Country Link
US (2) US10058634B2 (es)
EP (1) EP2424581B1 (es)
JP (1) JP5814913B2 (es)
CN (2) CN105214143A (es)
CA (1) CA2760187C (es)
MX (1) MX342897B (es)
SG (1) SG175373A1 (es)
WO (1) WO2010129328A2 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11529440B2 (en) 2011-05-20 2022-12-20 Surmodics, Inc. Delivery of hydrophobic active agent particles

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2760187C (en) 2009-04-28 2018-01-02 Ralph A. Chappa Devices and methods for delivery of bioactive agents
JP2013514278A (ja) 2009-12-18 2013-04-25 インターフェース バイオロジクス,インコーポレーテッド 自己集合コーティングからの薬物の局所送達
US10213529B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US9757497B2 (en) 2011-05-20 2017-09-12 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
CN102512747A (zh) * 2011-12-27 2012-06-27 微创医疗器械(上海)有限公司 药物洗脱球囊导管
US9375517B2 (en) 2012-01-18 2016-06-28 Surmodies, Inc. Lubricious medical device coating with low particulates
US9827401B2 (en) 2012-06-01 2017-11-28 Surmodics, Inc. Apparatus and methods for coating medical devices
MX351261B (es) 2012-06-01 2017-10-06 Surmodics Inc Aparato y método para recubrir catéteres con globo.
WO2014071387A1 (en) 2012-11-05 2014-05-08 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
DE102013014821A1 (de) * 2013-09-10 2015-03-12 Alexander Rübben Gefäßendoprothesenbeschichtung
DE102013110294B4 (de) 2013-09-18 2016-07-07 Innora Gmbh Limus-Depot-Formulierung auf Ballonkathetern
CN103948972B (zh) * 2014-05-04 2016-06-29 广东博迈医疗器械有限公司 一种表面带有改性涂层的扩张球囊及其制备工艺
US10124088B2 (en) * 2014-09-29 2018-11-13 Surmodics, Inc. Lubricious medical device elements
US10342898B2 (en) 2015-12-29 2019-07-09 Surmodics, Inc. Lubricious coatings with surface salt groups
US11174447B2 (en) 2015-12-29 2021-11-16 Surmodics, Inc. Lubricious coatings with surface salt groups
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces
EP3796948A4 (en) 2018-05-22 2022-03-02 Interface Biologics Inc. COMPOSITIONS AND METHODS FOR ADMINISTRATION OF MEDICATIONS TO A VESSEL WALL
US11628466B2 (en) 2018-11-29 2023-04-18 Surmodics, Inc. Apparatus and methods for coating medical devices
US11819590B2 (en) 2019-05-13 2023-11-21 Surmodics, Inc. Apparatus and methods for coating medical devices
WO2021081036A1 (en) * 2019-10-21 2021-04-29 Biocoat, Inc. Uv cure coatings for medical devices

Family Cites Families (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3389099A (en) 1966-02-23 1968-06-18 Koppers Co Inc Ultraviolet light stabilizers for plastic materials
CH616337A5 (es) * 1977-10-21 1980-03-31 Schneider Medintag Ag
US4722906A (en) * 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4490421A (en) * 1983-07-05 1984-12-25 E. I. Du Pont De Nemours And Company Balloon and manufacture thereof
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US5041089A (en) * 1987-12-11 1991-08-20 Devices For Vascular Intervention, Inc. Vascular dilation catheter construction
US5087246A (en) * 1988-12-29 1992-02-11 C. R. Bard, Inc. Dilation catheter with fluted balloon
US5201753A (en) 1989-03-17 1993-04-13 Merit Medical Systems, Inc. Totally self-contained, digitally controlled, disposable syringe inflation system, and method for monitoring, displaying and recording balloon catheter inflation data
US4973993A (en) 1989-07-11 1990-11-27 Hewlett-Packard Company Ink-quantity and low ink sensing for ink-jet printers
US5318587A (en) * 1989-08-25 1994-06-07 C. R. Bard, Inc. Pleated balloon dilatation catheter and method of use
EP0479730B1 (de) * 1990-10-04 1995-04-19 Schneider (Europe) Ag Ballondilationskatheter
JP2555298B2 (ja) * 1990-11-10 1996-11-20 テルモ株式会社 カテーテル用バルーン、カテーテル用バルーンの製造方法およびバルーンカテーテル
US5195969A (en) * 1991-04-26 1993-03-23 Boston Scientific Corporation Co-extruded medical balloons and catheter using such balloons
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5500180A (en) * 1992-09-30 1996-03-19 C. R. Bard, Inc. Method of making a distensible dilatation balloon using a block copolymer
US5414075A (en) * 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification
US5297607A (en) 1992-12-15 1994-03-29 Pierre Beauchamp Sheet curtain with vertical blind actuating mechanism
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5382234A (en) * 1993-04-08 1995-01-17 Scimed Life Systems, Inc. Over-the-wire balloon catheter
US5344402A (en) * 1993-06-30 1994-09-06 Cardiovascular Dynamics, Inc. Low profile perfusion catheter
CN100998565A (zh) 1993-07-19 2007-07-18 血管技术药物公司 抗血管生长组合物及使用方法
DE69434598T3 (de) 1993-07-29 2010-07-29 The United States Of America Represented By The Secretary, Department Of Health And Human Services Verwendung von Paclitaxel und seinen Derivaten zur Herstellung eines Medikaments für die Behandlung von Restenose
US6896842B1 (en) * 1993-10-01 2005-05-24 Boston Scientific Corporation Medical device balloons containing thermoplastic elastomers
CA2160487C (en) * 1994-02-17 2003-09-23 Lixiao Wang Process improvements for preparing catheter balloons
DK0748232T4 (da) * 1994-03-02 2009-01-19 Boston Scient Scimed Inc Kateterballoner af blokcopolymerelastomerer
CA2188407A1 (en) * 1994-04-20 1995-11-02 Ronald J. Solar Active perfusion dilatation catheter
US5632773A (en) 1994-05-03 1997-05-27 Allergan, Inc. Biostable corneal implants
US5667493A (en) * 1994-12-30 1997-09-16 Janacek; Jaroslav Dilation catheter
US5833657A (en) 1995-05-30 1998-11-10 Ethicon, Inc. Single-walled balloon catheter with non-linear compliance characteristic
US6774278B1 (en) 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5714360A (en) 1995-11-03 1998-02-03 Bsi Corporation Photoactivatable water soluble cross-linking agents containing an onium group
WO1997017098A1 (en) * 1995-11-08 1997-05-15 Scimed Life Systems, Inc. Method of balloon formation by cold drawing/necking
ES2226120T3 (es) 1997-03-31 2005-03-16 Boston Scientific Limited Inhibidor terapeutico de celulas del musculo liso vascular.
JPH10328293A (ja) 1997-06-04 1998-12-15 Unitika Ltd 医療用具及びその製造方法
US6121027A (en) 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US6506895B2 (en) 1997-08-15 2003-01-14 Surmodics, Inc. Photoactivatable nucleic acids
US6762019B2 (en) 1997-09-30 2004-07-13 Surmodics, Inc. Epoxide polymer surfaces
US6465178B2 (en) 1997-09-30 2002-10-15 Surmodics, Inc. Target molecule attachment to surfaces
US5858653A (en) 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
EP1028761A1 (en) 1997-11-07 2000-08-23 Salviac Limited Biostable polycarbonate urethane products
US6517515B1 (en) * 1998-03-04 2003-02-11 Scimed Life Systems, Inc. Catheter having variable size guide wire lumen
US6007833A (en) * 1998-03-19 1999-12-28 Surmodics, Inc. Crosslinkable macromers bearing initiator groups
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
DE19814730A1 (de) 1998-04-02 1999-10-07 Basf Ag Verwendung von N-Vinyllacram oder N-Vinylamin haltigen Copolymeren als Matrix zur Herstellung von festen pharmazeutischen und kosmetischen Darreichungsformen
CA2330134A1 (en) * 1998-05-15 1999-11-25 Medgination, Inc. Enhanced balloon dilatation system
US6254634B1 (en) * 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
KR20010072816A (ko) 1998-08-20 2001-07-31 쿡 인코포레이티드 피복된 삽입용 의료 장치
US6613066B1 (en) * 1998-10-05 2003-09-02 Kaneka Corporation Balloon catheter and production method therefor
US6340465B1 (en) 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
AU4606700A (en) 1999-05-07 2000-11-21 Salviac Limited A tissue engineering scaffold
JP4813712B2 (ja) 1999-08-09 2011-11-09 ザ ジェネラル ホスピタル コーポレーション 薬物−担体複合体およびその使用方法
US6278018B1 (en) 1999-12-14 2001-08-21 Surmodics, Inc. Surface coating agents
KR100416242B1 (ko) 1999-12-22 2004-01-31 주식회사 삼양사 약물전달체용 생분해성 블록 공중합체의 액체 조성물 및이의 제조방법
US6589665B2 (en) 2000-05-30 2003-07-08 Novartis Ag Coated articles
US6444324B1 (en) 2000-12-01 2002-09-03 Scimed Life Systems, Inc. Lubricated catheter balloon
US6623504B2 (en) * 2000-12-08 2003-09-23 Scimed Life Systems, Inc. Balloon catheter with radiopaque distal tip
US6663662B2 (en) 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US7771468B2 (en) * 2001-03-16 2010-08-10 Angiotech Biocoatings Corp. Medicated stent having multi-layer polymer coating
US7456025B2 (en) 2001-08-28 2008-11-25 Porex Corporation Sintered polymer membrane for analyte detection device
DE60204158T2 (de) 2001-10-05 2006-02-02 SurModics, Inc., Eden Prairie Beschichtungen mit immobilisierten partikeln sowie verwendungen derselben
AU2002365360A1 (en) 2001-11-28 2003-06-10 Biopolymed Inc. Biologically active non-antigenic copolymer and conjugates thereof and methods for producing the same
US7348055B2 (en) 2001-12-21 2008-03-25 Surmodics, Inc. Reagent and method for providing coatings on surfaces
US7797033B2 (en) 2002-04-08 2010-09-14 Smart Pill Corporation Method of using, and determining location of, an ingestible capsule
DK1521603T3 (da) 2002-07-12 2011-04-18 Cook Inc Coated medicinsk anordning
EP1530456A2 (en) 2002-08-23 2005-05-18 Munich Biotech AG Non-vesicular cationic lipid formulations
US20040044404A1 (en) * 2002-08-30 2004-03-04 Stucke Sean M. Retention coatings for delivery systems
GB0221942D0 (en) 2002-09-20 2002-10-30 Univ Strathclyde Drug delivery
DE10244847A1 (de) * 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
US8202530B2 (en) 2002-09-27 2012-06-19 Advanced Cardiovascular Systems, Inc. Biocompatible coatings for stents
JP4575361B2 (ja) * 2003-02-26 2010-11-04 ボストン サイエンティフィック リミテッド バルーンカテーテル
IES20030294A2 (en) 2003-04-17 2004-10-20 Medtronic Vascular Connaught Coating for biomedical devices
US7544381B2 (en) 2003-09-09 2009-06-09 Boston Scientific Scimed, Inc. Lubricious coatings for medical device
EP1521332B1 (en) 2003-09-30 2007-08-15 Lucent Technologies Network Systems GmbH A compact multiple-band antenna arrangement
US7309593B2 (en) 2003-10-01 2007-12-18 Surmodics, Inc. Attachment of molecules to surfaces
WO2005037338A1 (en) 2003-10-14 2005-04-28 Cook Incorporated Hydrophilic coated medical device
US20050181015A1 (en) 2004-02-12 2005-08-18 Sheng-Ping (Samuel) Zhong Layered silicate nanoparticles for controlled delivery of therapeutic agents from medical articles
US8003122B2 (en) 2004-03-31 2011-08-23 Cordis Corporation Device for local and/or regional delivery employing liquid formulations of therapeutic agents
JP5026956B2 (ja) 2004-05-12 2012-09-19 サーモディクス,インコーポレイティド 医療用具のための天然生分解性多糖コーティング
CN1950114A (zh) 2004-05-12 2007-04-18 苏尔莫迪克斯公司 用于医疗物品的天然生物可降解的多糖涂层
US7758892B1 (en) 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
US20050281857A1 (en) * 2004-05-25 2005-12-22 Heyer Toni M Methods and reagents for preparing biomolecule-containing coatings
US7356368B2 (en) 2004-07-21 2008-04-08 Boston Scientific Scimed, Inc. Light-activated anti-infective coatings and devices made thereof
US7807750B2 (en) * 2004-08-06 2010-10-05 Surmodics, Inc. Thermally-reactive polymers
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
EP1824460B1 (en) 2004-11-10 2014-12-24 Tolmar Therapeutics, Inc. A stabilized polymeric delivery system
CN1964750A (zh) 2005-04-06 2007-05-16 苏莫迪克斯公司 用于医疗用具的生物活性的涂料组合物
US7772393B2 (en) 2005-06-13 2010-08-10 Innovative Surface Technologies, Inc. Photochemical crosslinkers for polymer coatings and substrate tie-layer
EP1904118B1 (en) 2005-07-20 2018-01-17 Surmodics, Inc. Polymeric coatings and methods for cell attachment
US20070141365A1 (en) 2005-08-26 2007-06-21 Jelle Bruce M Silane Coating Compositions, Coating Systems, and Methods
AU2006284657B2 (en) 2005-08-31 2012-07-19 Abraxis Bioscience, Llc Compositions and methods for preparation of poorly water soluble drugs with increased stability
WO2007056338A2 (en) * 2005-11-08 2007-05-18 Surmodics, Inc. Ultra-thin photo-polymeric coatings and uses thereof
US7919108B2 (en) 2006-03-10 2011-04-05 Cook Incorporated Taxane coatings for implantable medical devices
FR2897354A1 (fr) 2006-02-16 2007-08-17 Arkema Sa Nouvelle utilisation d'un copolymere comprenant des blocs polyamide et des blocs polyethers provenant au moins en partie du polytrimethylene ether glycol
US7875284B2 (en) * 2006-03-10 2011-01-25 Cook Incorporated Methods of manufacturing and modifying taxane coatings for implantable medical devices
US8092818B2 (en) 2006-05-17 2012-01-10 Boston Scientific Scimed, Inc. Medical devices having bioactive surfaces
FR2902431B1 (fr) 2006-06-14 2013-04-26 Arkema France Copolymeres a motif amides et a motif ethers ayant des proprietes optique ameliorees
US20080175887A1 (en) * 2006-11-20 2008-07-24 Lixiao Wang Treatment of Asthma and Chronic Obstructive Pulmonary Disease With Anti-proliferate and Anti-inflammatory Drugs
CN101622020B (zh) 2007-02-28 2015-07-01 帝斯曼知识产权资产管理有限公司 亲水性涂层
MY148410A (en) 2007-02-28 2013-04-30 Dsm Ip Assets Bv Hydrophilic coating
CA2680825C (en) 2007-03-22 2013-10-29 Cytotech Labs, Llc Topical formulations having enhanced bioavailability
KR100904207B1 (ko) 2007-06-01 2009-06-25 (주) 태웅메디칼 스텐트용 약물 방출 코팅제, 그의 제조방법 및 이 코팅제로 코팅된 약물 방출 스텐트
US20090043378A1 (en) * 2007-08-10 2009-02-12 Medtronic Vascular, Inc. Biocompatible Polymer System for Extended Drug Release
US20090226501A1 (en) 2007-12-07 2009-09-10 Boston Scientific Scimed, Inc. Drug coated stent with endosome-disrupting conjugate
KR20100132486A (ko) 2008-03-12 2010-12-17 안게스 엠지 인코포레이티드 약제 용출형 카테터 및 그 제조방법
WO2009121629A1 (en) 2008-04-04 2009-10-08 Medigene Ag Solubilisation method
US9295820B2 (en) 2008-08-14 2016-03-29 Surmodics, Inc. Method and apparatus for coating balloon catheters
WO2010042471A2 (en) 2008-10-07 2010-04-15 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents to body lumens
US20100130837A1 (en) 2008-11-25 2010-05-27 The Smart Pill Corporation Modular ingestible capsule
US20110257339A1 (en) 2008-12-22 2011-10-20 Basf Se Method for stabilizing polymers
WO2010111517A1 (en) 2009-03-25 2010-09-30 Northeastern University Stable polyelectrolyte coated nanoparticles
WO2010118232A1 (en) 2009-04-09 2010-10-14 Elan Pharma International Limited Controlled-release clozapine compositions
CA2760187C (en) 2009-04-28 2018-01-02 Ralph A. Chappa Devices and methods for delivery of bioactive agents
EP2253337A1 (en) 2009-05-18 2010-11-24 Encapson B.V. Balloon catheter comprising pressure sensitive microcapsules.
ES2550634T3 (es) 2009-07-10 2015-11-11 Boston Scientific Scimed, Inc. Uso de nanocristales para un balón de suministro de fármaco
JP5693456B2 (ja) 2009-08-26 2015-04-01 大塚メディカルデバイス株式会社 管腔内留置用医療デバイス及びその製造方法
WO2011052089A1 (ja) 2009-11-02 2011-05-05 ニチバン株式会社 電離性放射線で架橋したヒドロゲルから成る生体内薬剤徐放用担体材料及びその製造方法
WO2011072199A2 (en) 2009-12-10 2011-06-16 Surmodics, Inc. Water-soluble degradable photo-crosslinker
RU2594729C2 (ru) 2010-03-30 2016-08-20 Сурмодикс, Инк. Разлагаемое фотосшивающее средство
US20120039983A1 (en) 2010-08-11 2012-02-16 Uhrich Kathryn E Amphiphilic macromolecule-lipid complexes
EP2658527B1 (en) 2010-12-30 2022-11-30 Micell Technologies, Inc. Nanoparticle and surface-modified particulate coatings, coated balloons, and methods therefore
US20120177910A1 (en) 2011-01-11 2012-07-12 Boston Scientific Scimed, Inc. Coated Medical Devices
US9757497B2 (en) 2011-05-20 2017-09-12 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US10213529B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US9861727B2 (en) 2011-05-20 2018-01-09 Surmodics, Inc. Delivery of hydrophobic active agent particles
WO2012170706A2 (en) 2011-06-08 2012-12-13 Surmodics, Inc. Photo-vinyl linking agents
US8697112B2 (en) 2011-07-08 2014-04-15 Covalon Technologies Method for treating a surface with a coating comprising a microencapsulated therapeutic agent and device with treated surface
US9375517B2 (en) 2012-01-18 2016-06-28 Surmodies, Inc. Lubricious medical device coating with low particulates
US20130303983A1 (en) 2012-05-09 2013-11-14 Cook Medical Technologies Llc Coated medical devices including a water-insoluble therapeutic agent
US9410044B2 (en) 2012-05-11 2016-08-09 Surmodics, Inc. Boron-containing linking agents
WO2014071387A1 (en) 2012-11-05 2014-05-08 Surmodics, Inc. Composition and method for delivery of hydrophobic active agents
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
US9629945B2 (en) 2012-12-12 2017-04-25 Surmodics, Inc. Stilbene-based reactive compounds, polymeric matrices formed therefrom, and articles visualizable by fluorescence
EP4276161A3 (en) 2013-01-04 2024-01-17 SurModics, Inc. Low particulate lubricious coating with vinyl pyrrolidone and acidic polymer-containing layers
KR102293280B1 (ko) 2013-03-15 2021-08-23 타리스 바이오메디컬 엘엘씨 약물-투과성 구성요소를 가지는 약물 전달 장치 및 방법
CA2912690C (en) 2013-05-16 2022-05-03 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
BR112017016342B1 (pt) 2015-01-29 2021-05-11 Surmodics, Inc revestimento de entrega de fármacos
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11529440B2 (en) 2011-05-20 2022-12-20 Surmodics, Inc. Delivery of hydrophobic active agent particles

Also Published As

Publication number Publication date
JP2012525225A (ja) 2012-10-22
US10058634B2 (en) 2018-08-28
EP2424581A2 (en) 2012-03-07
CN102427834A (zh) 2012-04-25
CN105214143A (zh) 2016-01-06
EP2424581B1 (en) 2017-03-01
CA2760187C (en) 2018-01-02
MX2011011389A (es) 2011-11-18
US20180272040A1 (en) 2018-09-27
WO2010129328A3 (en) 2011-01-27
JP5814913B2 (ja) 2015-11-17
WO2010129328A2 (en) 2010-11-11
US20100272774A1 (en) 2010-10-28
CA2760187A1 (en) 2010-11-11
SG175373A1 (en) 2011-11-28
US11027049B2 (en) 2021-06-08

Similar Documents

Publication Publication Date Title
MX342897B (es) Dispositivos y metodos para suministrar agentes bioactivos.
WO2013009998A3 (en) Device for delivery of antimicrobial agent into trans-dermal catheter
MY162248A (en) Hydrophilic coating
WO2010021757A3 (en) Implantable medical device coatings with biodegradable elastomer and releasable taxane agent
WO2011147407A3 (de) Katheterballon beschichtet mit einem antirestenotischen wirkstoff und einem transportfördernden molekulardispersionsmittel
PL2240220T3 (pl) Wszczepialne urządzenia do podawania leków i aparaty do napełniania urządzeń
WO2010101722A3 (en) Polymer for creating hemocompatible surface
WO2007130366A3 (en) Surface interactions to improve retention of medical devices
DE602005013405D1 (de) Stents mit wirkstofffreisetzungsbeschichtungen
WO2012149494A3 (en) Coating compositions, methods and coated devices
WO2009129503A3 (en) Block copolymer comprising at least one polyester block and a poly(ethylene glycol) block
WO2010135418A3 (en) Implantable medical devices for therapeutic agent delivery
WO2008140482A3 (en) Medical devices having coatings for controlled therapeutic agent delivery
WO2008042434A3 (en) Systems and devices for delivering an implant
WO2007084361A3 (en) Coated medical devices and methods of making the same
WO2007139845A3 (en) Systems and methods for introducing and applying a bandage structure within a body lumen or hollow body organ
WO2009155328A3 (en) Endoprosthesis coating
WO2007126606A3 (en) Controlled degradation and drug release in stents
MX2014007213A (es) Modificaciones luminales para cateteres.
WO2006058234A3 (en) Medical devices with highly flexible coated hypotube
WO2012091956A3 (en) Continuous indentation lateral lobe apparatus and method
WO2009086112A3 (en) Apparatus and methods for delivering therapeutic agents
IL205196A0 (en) Implant delivery device and method
EP2065920A4 (en) MOBILE BODY DRIVING METHOD AND MOBILE BODY DRIVE SYSTEM, STRUCTURE MANUFACTURING METHOD AND DEVICE, EXPOSURE METHOD AND DEVICE AND CONSTRUCTION MANUFACTURING METHOD
EP2503615A4 (en) DEVICE, THIN-LAYER TRANSISTOR, METHOD FOR PRODUCING THE DEVICE AND METHOD FOR PRODUCING THE THIN-LAYER TRANSISTOR

Legal Events

Date Code Title Description
FG Grant or registration