MX340928B - Derivados de oxazolina e isoxazolina como moduladores de canales de calcio de liberación activa (crac). - Google Patents

Derivados de oxazolina e isoxazolina como moduladores de canales de calcio de liberación activa (crac).

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Publication number
MX340928B
MX340928B MX2013004812A MX2013004812A MX340928B MX 340928 B MX340928 B MX 340928B MX 2013004812 A MX2013004812 A MX 2013004812A MX 2013004812 A MX2013004812 A MX 2013004812A MX 340928 B MX340928 B MX 340928B
Authority
MX
Mexico
Prior art keywords
oxazoline
crac
isoxazoline derivatives
crac modulators
modulators
Prior art date
Application number
MX2013004812A
Other languages
English (en)
Other versions
MX2013004812A (es
Inventor
Rao Irlapati Nageswara
Keruji Deshmukh Gokul
Pandurang Karche Vijay
Madhukar Jachak Santosh
Sinha Neelima
P Palle Venkata
Kumar Kamboj Rajender
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Publication of MX2013004812A publication Critical patent/MX2013004812A/es
Publication of MX340928B publication Critical patent/MX340928B/es

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    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La presente invención se relaciona con compuestos de la Fórmula (I) junto con procesos para su preparación que son útiles para el trato, prevención y/o manejo de las enfermedades, trastornos, síndromes o condiciones asociados con la modulación de CRAC. La invención además se relaciona con métodos para el trato, prevención, manejo y/o disminución de las enfermedades, trastornos, síndromes o condiciones asociadas con la modulación de CRAC de la Fórmula (I).
MX2013004812A 2010-10-30 2011-10-31 Derivados de oxazolina e isoxazolina como moduladores de canales de calcio de liberación activa (crac). MX340928B (es)

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PCT/IN2011/000749 WO2012056478A1 (en) 2010-10-30 2011-10-31 Oxazole and isoxazole crac modulators

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CN103228636A (zh) 2013-07-31
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JP2016074704A (ja) 2016-05-12
EA023298B1 (ru) 2016-05-31
ZA201303794B (en) 2015-08-26
SI2632906T1 (sl) 2016-08-31
US9169242B2 (en) 2015-10-27
KR20130106410A (ko) 2013-09-27
AU2016200651A1 (en) 2016-02-25
PH12013500831A1 (en) 2019-06-03
PT2632906T (pt) 2016-07-15
CN105566311A (zh) 2016-05-11
JP5848355B2 (ja) 2016-01-27
SMT201600192B (it) 2016-08-31
CA2814768C (en) 2019-02-12
CN103228636B (zh) 2016-02-10
AU2011322068B2 (en) 2015-11-05
BR112013010643A2 (pt) 2016-08-09
CY1117706T1 (el) 2017-05-17
IL225722A0 (en) 2013-06-27
HK1187918A1 (zh) 2014-04-17
WO2012056478A8 (en) 2012-06-14
JP2013542220A (ja) 2013-11-21
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ES2578290T3 (es) 2016-07-22
MY162689A (en) 2017-07-14
US20170304299A1 (en) 2017-10-26
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MX2013004812A (es) 2013-10-03
HUE029172T2 (hu) 2017-02-28
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US10292981B2 (en) 2019-05-21
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