CR20150500A - Derivados de 3-acetilamino-1 (fenil-heteroaril- aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos - Google Patents

Derivados de 3-acetilamino-1 (fenil-heteroaril- aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos

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Publication number
CR20150500A
CR20150500A CR20150500A CR20150500A CR20150500A CR 20150500 A CR20150500 A CR 20150500A CR 20150500 A CR20150500 A CR 20150500A CR 20150500 A CR20150500 A CR 20150500A CR 20150500 A CR20150500 A CR 20150500A
Authority
CR
Costa Rica
Prior art keywords
phenyl
heteroaril
aminocarbonil
acetyllamin
carbonylamine
Prior art date
Application number
CR20150500A
Other languages
English (en)
Inventor
Kai Thede
William J Scott
Eckhard Bender
Stefan Golz
Andrea Hägebarth
Philip Lienau
Florian Puehler
Daniel Basting
Dirk Schneider
Manfred Möwes
Anja Richter
Ludwig Zorn
Ningshu Liu
Ursula Mönning
Franziska Siegel
Original Assignee
Bayer Pharma Aktiengesellchaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma Aktiengesellchaft filed Critical Bayer Pharma Aktiengesellchaft
Publication of CR20150500A publication Critical patent/CR20150500A/es

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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

La presente invención se relaciona con N-(fenilheteroaril)-3-acetilamino-benzamidas sustituidas y N-[3-(acetilamino)fenil]- fenil-heteroaril-carboxamidas de fórmula general (I) como se describe y se define en la presente, con métodos de preparación de dichos compuestos, con compuestos intermediarios útiles parapreparar dichos compuestos.
CR20150500A 2013-03-20 2015-09-18 Derivados de 3-acetilamino-1 (fenil-heteroaril- aminocarbonil o fenil-heteroaril-carbonilamino) benceno para el tratamiento de desordenes hiperproliferativos CR20150500A (es)

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PCT/EP2014/055300 WO2014147021A2 (en) 2013-03-20 2014-03-17 Novel compounds

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PH12015502192A1 (en) 2016-01-25
CN105228982B (zh) 2018-03-27
JP2016519674A (ja) 2016-07-07
UY35492A (es) 2014-10-31
CL2015002814A1 (es) 2016-04-01
MX2015013348A (es) 2016-01-20
BR112015024073A2 (pt) 2018-05-08
HK1217706A1 (zh) 2017-01-20
CN105228982A (zh) 2016-01-06
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CA2907535A1 (en) 2014-09-25
US20160263122A1 (en) 2016-09-15
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