MX339083B - Proteinas de enlace a cd127. - Google Patents

Proteinas de enlace a cd127.

Info

Publication number
MX339083B
MX339083B MX2012008765A MX2012008765A MX339083B MX 339083 B MX339083 B MX 339083B MX 2012008765 A MX2012008765 A MX 2012008765A MX 2012008765 A MX2012008765 A MX 2012008765A MX 339083 B MX339083 B MX 339083B
Authority
MX
Mexico
Prior art keywords
binding proteins
antigen binding
diseases
disorders
humans
Prior art date
Application number
MX2012008765A
Other languages
English (en)
Other versions
MX2012008765A (es
Inventor
Ian Kirby
Alexander H Taylor
Thomas Matthew Webb
Yu Xue
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of MX2012008765A publication Critical patent/MX2012008765A/es
Publication of MX339083B publication Critical patent/MX339083B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente invención se refiere a proteínas de enlace a antígeno que se enlazan al receptor de lL-7 humano (CD127). Las proteínas de enlace a antígeno típicamente son anticuerpos, y son útiles en el tratamiento de enfermedades o trastornos en seres humanos, particularmente enfermedades autoinmunes, tales como la esclerosis múltiple.
MX2012008765A 2010-01-28 2011-01-26 Proteinas de enlace a cd127. MX339083B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29901010P 2010-01-28 2010-01-28
PCT/US2011/022507 WO2011094259A2 (en) 2010-01-28 2011-01-26 Cd127 binding proteins

Publications (2)

Publication Number Publication Date
MX2012008765A MX2012008765A (es) 2012-09-07
MX339083B true MX339083B (es) 2016-04-01

Family

ID=44320081

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2012008765A MX339083B (es) 2010-01-28 2011-01-26 Proteinas de enlace a cd127.

Country Status (26)

Country Link
US (2) US8940303B2 (es)
EP (1) EP2528947A4 (es)
JP (1) JP5850860B2 (es)
KR (1) KR20130028055A (es)
CN (1) CN102812046B (es)
AR (1) AR080027A1 (es)
AU (1) AU2011209713B2 (es)
BR (1) BR112012018914A2 (es)
CA (1) CA2787070A1 (es)
CL (1) CL2012002081A1 (es)
CO (1) CO6592067A2 (es)
CR (1) CR20120404A (es)
EA (1) EA023700B1 (es)
IL (1) IL220899A (es)
MA (1) MA34004B1 (es)
MX (1) MX339083B (es)
MY (1) MY160590A (es)
NZ (1) NZ601271A (es)
PE (2) PE20170687A1 (es)
PH (1) PH12012501549A1 (es)
SG (1) SG182590A1 (es)
TW (1) TWI489996B (es)
UA (1) UA104663C2 (es)
UY (1) UY33202A (es)
WO (1) WO2011094259A2 (es)
ZA (1) ZA201205624B (es)

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EP2955196A1 (en) * 2014-06-10 2015-12-16 Effimune Antibodies directed against CD127
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Also Published As

Publication number Publication date
PE20121702A1 (es) 2012-12-14
CO6592067A2 (es) 2013-01-02
MY160590A (en) 2017-03-15
IL220899A0 (en) 2012-09-24
US20120282254A1 (en) 2012-11-08
BR112012018914A2 (pt) 2017-07-25
EA023700B1 (ru) 2016-07-29
KR20130028055A (ko) 2013-03-18
CL2012002081A1 (es) 2012-12-14
PE20170687A1 (es) 2017-06-13
TW201136607A (en) 2011-11-01
MA34004B1 (fr) 2013-02-01
TWI489996B (zh) 2015-07-01
CR20120404A (es) 2012-10-04
WO2011094259A2 (en) 2011-08-04
CN102812046B (zh) 2015-02-25
CN102812046A (zh) 2012-12-05
US8940303B2 (en) 2015-01-27
PH12012501549A1 (en) 2016-09-09
JP5850860B2 (ja) 2016-02-03
SG182590A1 (en) 2012-08-30
WO2011094259A3 (en) 2011-09-29
EP2528947A4 (en) 2013-09-18
US9150653B2 (en) 2015-10-06
MX2012008765A (es) 2012-09-07
UY33202A (es) 2011-08-31
JP2013517799A (ja) 2013-05-20
CA2787070A1 (en) 2011-08-04
AU2011209713A1 (en) 2012-09-13
ZA201205624B (en) 2014-01-29
AR080027A1 (es) 2012-03-07
EP2528947A2 (en) 2012-12-05
US20110200585A1 (en) 2011-08-18
EA201290589A1 (ru) 2013-05-30
NZ601271A (en) 2014-09-26
UA104663C2 (xx) 2014-02-25
IL220899A (en) 2017-08-31
AU2011209713B2 (en) 2014-04-03

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