MX337864B - Metodo mejorado para producir analgesicos. - Google Patents

Metodo mejorado para producir analgesicos.

Info

Publication number
MX337864B
MX337864B MX2009006283A MX2009006283A MX337864B MX 337864 B MX337864 B MX 337864B MX 2009006283 A MX2009006283 A MX 2009006283A MX 2009006283 A MX2009006283 A MX 2009006283A MX 337864 B MX337864 B MX 337864B
Authority
MX
Mexico
Prior art keywords
oxymorphone hydrochloride
analgesics
making
improved method
oxymorphone
Prior art date
Application number
MX2009006283A
Other languages
English (en)
Other versions
MX2009006283A (es
Inventor
Jen-Sen Dung
Erno M Keskeny
James J Mencel
Original Assignee
Johnson Matthey Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37712066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX337864(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Johnson Matthey Plc filed Critical Johnson Matthey Plc
Publication of MX2009006283A publication Critical patent/MX2009006283A/es
Publication of MX337864B publication Critical patent/MX337864B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Abstract

Un analgésico mejorado de clorhidrato de oximorfona contiene menos de 10 ppm de cetonas alfa, beta insaturadas y preparaciones farmacéuticas que comprenden ese clorhidrato de oximorfona. El clorhidrato de oximorfona es producir reduciendo una materia prima de clorhidrato de oximorfona usando hidrógeno gaseosos y bajo acidez específica, un sistema de solventes y condiciones de temperatura específicas. Un polimorfo específico clorhidrato de oximorfona puede ser obtenido por hidratación.
MX2009006283A 2006-12-14 2007-12-14 Metodo mejorado para producir analgesicos. MX337864B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0624880.1A GB0624880D0 (en) 2006-12-14 2006-12-14 Improved method for making analgesics
PCT/GB2007/050758 WO2008072018A1 (en) 2006-12-14 2007-12-14 Improved method for making analgesics

Publications (2)

Publication Number Publication Date
MX2009006283A MX2009006283A (es) 2009-10-12
MX337864B true MX337864B (es) 2016-03-23

Family

ID=37712066

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009006283A MX337864B (es) 2006-12-14 2007-12-14 Metodo mejorado para producir analgesicos.

Country Status (13)

Country Link
US (1) US7851482B2 (es)
EP (1) EP2102213A1 (es)
JP (2) JP4786748B2 (es)
CN (2) CN102391271B (es)
AU (1) AU2007331223B2 (es)
BR (1) BRPI0720232A2 (es)
CA (1) CA2672644A1 (es)
GB (1) GB0624880D0 (es)
MX (1) MX337864B (es)
NO (1) NO20092503L (es)
RU (1) RU2422445C2 (es)
WO (1) WO2008072018A1 (es)
ZA (1) ZA200904317B (es)

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JP2017502991A (ja) 2014-01-15 2017-01-26 ローズ テクノロジーズ 改良されたオキシコドン合成のための方法
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Also Published As

Publication number Publication date
US20080146601A1 (en) 2008-06-19
JP4786748B2 (ja) 2011-10-05
GB0624880D0 (en) 2007-01-24
AU2007331223B2 (en) 2010-08-26
JP2011201906A (ja) 2011-10-13
MX2009006283A (es) 2009-10-12
AU2007331223A1 (en) 2008-06-19
JP2010513260A (ja) 2010-04-30
US7851482B2 (en) 2010-12-14
CN102391271B (zh) 2015-12-09
RU2009126774A (ru) 2011-01-20
RU2422445C2 (ru) 2011-06-27
CA2672644A1 (en) 2008-06-19
WO2008072018A1 (en) 2008-06-19
BRPI0720232A2 (pt) 2013-12-24
NO20092503L (no) 2009-08-27
CN102391271A (zh) 2012-03-28
CN101652371A (zh) 2010-02-17
ZA200904317B (en) 2010-08-25
EP2102213A1 (en) 2009-09-23

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