MX2022015804A - Agente profilactico o terapeutico para porfiria. - Google Patents
Agente profilactico o terapeutico para porfiria.Info
- Publication number
- MX2022015804A MX2022015804A MX2022015804A MX2022015804A MX2022015804A MX 2022015804 A MX2022015804 A MX 2022015804A MX 2022015804 A MX2022015804 A MX 2022015804A MX 2022015804 A MX2022015804 A MX 2022015804A MX 2022015804 A MX2022015804 A MX 2022015804A
- Authority
- MX
- Mexico
- Prior art keywords
- porphyria
- pyrrolidin
- prophylactic
- phenyl
- therapeutic agent
- Prior art date
Links
- 241000097929 Porphyria Species 0.000 title abstract 3
- 208000010642 Porphyrias Diseases 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 230000000069 prophylactic effect Effects 0.000 title 1
- 229940124597 therapeutic agent Drugs 0.000 title 1
- 125000004575 3-pyrrolidinyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 4
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un fármaco para tratar o evitar porfiria, que comprende ácido 1-{2-[(3S,4R)-1-{[(3R,4R)-1-ciclopentil-3-fluoro-4-(4-metoxifenil )pirrolidin-3-il]carbonil}-4-(metoximetil)pirrolidin-3-il]-5-(tri fluorometil)fenil}piperidin-4-carboxílico o una sal o cocristal farmacéuticamente aceptables de éste como un ingrediente activo, en donde la dosis del ácido 1-{2-[(3S,4R)-1-{[(3R,4R)-1-ciclopenti l-3-fluoro-4-(4-metoxifenil)pirrolidin-3-il]carbonil}-4-(metoxime til)pirrolidin-3-il]-5-(trifluorometil)fenil}piperidin-4-carboxíl ico o la sal o cocristal farmacéuticamente aceptables de éste es de 50 a 500 mg/día.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2020100952 | 2020-06-10 | ||
JP2020134451 | 2020-08-07 | ||
PCT/JP2021/022036 WO2021251450A1 (ja) | 2020-06-10 | 2021-06-10 | ポルフィリン症の予防又は治療剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2022015804A true MX2022015804A (es) | 2023-04-05 |
Family
ID=78282128
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2022015804A MX2022015804A (es) | 2020-06-10 | 2021-06-10 | Agente profilactico o terapeutico para porfiria. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20230248713A1 (es) |
EP (1) | EP4166140A1 (es) |
JP (1) | JP6959478B1 (es) |
KR (1) | KR20230016006A (es) |
CN (1) | CN115942934A (es) |
AU (1) | AU2021289913B2 (es) |
BR (1) | BR112022025099A2 (es) |
CA (1) | CA3186880A1 (es) |
IL (1) | IL298952A (es) |
MX (1) | MX2022015804A (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2024029599A1 (ja) * | 2022-08-03 | 2024-02-08 | 田辺三菱製薬株式会社 | 1-{2-[(3s,4r)-1-{[(3r,4r)-1-シクロペンチル-3-フルオロ-4-(4-メトキシフェニル)ピロリジン-3-イル]カルボニル}-4-(メトキシメチル)ピロリジン-3-イル]-5-(トリフルオロメチル)フェニル}ピペリジン-4-カルボン酸もしくはその医薬的に許容し得る塩又は共結晶を含有する医薬組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE035074T2 (en) | 2006-08-31 | 2018-05-02 | Clinuvel Pharmaceuticals Ltd | Alpha-MSH derivatives for the treatment of photodermatoses |
CA2950072C (en) | 2014-05-29 | 2019-03-26 | Mitsubishi Tanabe Pharma Corporation | Novel pyrrolidine compound and application as melanocortin receptor agonist |
TWI834791B (zh) | 2018-12-28 | 2024-03-11 | 日商田邊三菱製藥股份有限公司 | 吡咯啶化合物的結晶 |
-
2021
- 2021-06-10 IL IL298952A patent/IL298952A/en unknown
- 2021-06-10 CN CN202180041935.2A patent/CN115942934A/zh active Pending
- 2021-06-10 JP JP2021536017A patent/JP6959478B1/ja active Active
- 2021-06-10 MX MX2022015804A patent/MX2022015804A/es unknown
- 2021-06-10 CA CA3186880A patent/CA3186880A1/en active Pending
- 2021-06-10 US US18/009,107 patent/US20230248713A1/en active Pending
- 2021-06-10 EP EP21821230.6A patent/EP4166140A1/en active Pending
- 2021-06-10 KR KR1020227045682A patent/KR20230016006A/ko active Search and Examination
- 2021-06-10 BR BR112022025099A patent/BR112022025099A2/pt unknown
- 2021-06-10 AU AU2021289913A patent/AU2021289913B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CA3186880A1 (en) | 2021-12-16 |
KR20230016006A (ko) | 2023-01-31 |
AU2021289913A1 (en) | 2023-02-02 |
US20230248713A1 (en) | 2023-08-10 |
JP6959478B1 (ja) | 2021-11-02 |
AU2021289913B2 (en) | 2024-03-28 |
CN115942934A (zh) | 2023-04-07 |
IL298952A (en) | 2023-02-01 |
JPWO2021251450A1 (es) | 2021-12-16 |
EP4166140A1 (en) | 2023-04-19 |
BR112022025099A2 (pt) | 2023-02-14 |
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