MX2021014747A - Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos. - Google Patents

Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos.

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Publication number
MX2021014747A
MX2021014747A MX2021014747A MX2021014747A MX2021014747A MX 2021014747 A MX2021014747 A MX 2021014747A MX 2021014747 A MX2021014747 A MX 2021014747A MX 2021014747 A MX2021014747 A MX 2021014747A MX 2021014747 A MX2021014747 A MX 2021014747A
Authority
MX
Mexico
Prior art keywords
systems
methods
chemical products
active pharmaceutical
pharmaceutical ingredients
Prior art date
Application number
MX2021014747A
Other languages
English (en)
Inventor
Timothy F Jamison
Klavs F Jensen
Allan Stuart Myerson
Jean- Christophe M Monbaliu
Mohsen Behnam
Shin Yee Wong
Nopphon Weeranoppanant
Eve Marie Revalor
Torsten Stelzer
Jie Chen
Andrea Adamo
David R Snead
Ping Zhang
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of MX2021014747A publication Critical patent/MX2021014747A/es

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0006—Controlling or regulating processes
    • B01J19/004—Multifunctional apparatus for automatic manufacturing of various chemical products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18—Stationary reactors having moving elements inside
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00002—Chemical plants
    • B01J2219/00004—Scale aspects
    • B01J2219/00011—Laboratory-scale plants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00788—Three-dimensional assemblies, i.e. the reactor comprising a form other than a stack of plates
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B—PERFORMING OPERATIONS; TRANSPORTING
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    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00907—Separation using membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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    • B01J2219/00909—Separation using filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00905—Separation
    • B01J2219/00918—Separation by adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/0095—Control aspects
    • B01J2219/00986—Microprocessor

Abstract

Se proporcionan generalmente los sistemas y métodos para sintetizar productos químicos, incluyendo ingredientes farmacéuticos activos, ciertos sistemas y métodos que se describen en la presente son capaces de fabricar múltiples productos químicos sin la necesidad de conectar o desconectar de manera fluida las unidades de operación cuando se cambia de hacer un producto químico a hacer otro producto químico.
MX2021014747A 2014-08-15 2017-02-14 Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos. MX2021014747A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462038039P 2014-08-15 2014-08-15

Publications (1)

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MX2021014747A true MX2021014747A (es) 2022-01-18

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ID=55304659

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MX2017002033A MX2017002033A (es) 2014-08-15 2015-08-14 Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos.
MX2021014747A MX2021014747A (es) 2014-08-15 2017-02-14 Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos.

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MX2017002033A MX2017002033A (es) 2014-08-15 2015-08-14 Sistemas y metodos para sintetizar productos quimicos, incluyendo ingredientes farmaceuticos activos.

Country Status (9)

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US (3) US10780410B2 (es)
EP (1) EP3180118A4 (es)
JP (4) JP6787881B2 (es)
KR (3) KR102482164B1 (es)
AU (3) AU2015301544A1 (es)
BR (1) BR112017002624B1 (es)
CA (1) CA2957410C (es)
MX (2) MX2017002033A (es)
WO (1) WO2016025803A1 (es)

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AU2019268159A1 (en) 2019-12-12
KR20170042330A (ko) 2017-04-18
KR102517182B1 (ko) 2023-04-04
WO2016025803A1 (en) 2016-02-18
JP2023123614A (ja) 2023-09-05
US11565230B2 (en) 2023-01-31
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AU2015301544A1 (en) 2017-03-02
US20230201787A1 (en) 2023-06-29
CA2957410C (en) 2023-07-04
CA2957410A1 (en) 2016-02-18
JP2017530096A (ja) 2017-10-12
BR112017002624A2 (pt) 2017-12-05
KR102482164B1 (ko) 2022-12-29
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JP2021193137A (ja) 2021-12-23
EP3180118A1 (en) 2017-06-21
US20180207604A1 (en) 2018-07-26
JP2020099903A (ja) 2020-07-02
US20200368710A1 (en) 2020-11-26
KR20220044863A (ko) 2022-04-11
KR20230049755A (ko) 2023-04-13
BR112017002624B1 (pt) 2021-04-13
MX2017002033A (es) 2017-08-14
AU2019268159B2 (en) 2022-01-13
AU2021286269B2 (en) 2023-07-20
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