MX2021006447A - Procedimiento de preparacion de particulas polimericas. - Google Patents

Procedimiento de preparacion de particulas polimericas.

Info

Publication number
MX2021006447A
MX2021006447A MX2021006447A MX2021006447A MX2021006447A MX 2021006447 A MX2021006447 A MX 2021006447A MX 2021006447 A MX2021006447 A MX 2021006447A MX 2021006447 A MX2021006447 A MX 2021006447A MX 2021006447 A MX2021006447 A MX 2021006447A
Authority
MX
Mexico
Prior art keywords
weight
polymeric particles
methacrylic acid
further monomers
polymerized units
Prior art date
Application number
MX2021006447A
Other languages
English (en)
Inventor
Manfred Assmus
Thomas Endres
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of MX2021006447A publication Critical patent/MX2021006447A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/12—Polymerisation in non-solvents
    • C08F2/16—Aqueous medium
    • C08F2/22—Emulsion polymerisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00—Processes of polymerisation
    • C08F2/001—Multistage polymerisation processes characterised by a change in reactor conditions without deactivating the intermediate polymer
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/14—Methyl esters, e.g. methyl (meth)acrylate
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/126—Polymer particles coated by polymer, e.g. core shell structures
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2800/00—Copolymer characterised by the proportions of the comonomers expressed
    • C08F2800/20—Copolymer characterised by the proportions of the comonomers expressed as weight or mass percentages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2333/04—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters
    • C08J2333/06—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers esters of esters containing only carbon, hydrogen, and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C08J2333/10—Homopolymers or copolymers of methacrylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polymerisation Methods In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

La invención se refiere a un procedimiento de preparación de partículas poliméricas, que comprende unidades polimerizadas de ácido metacrílico y otros monómeros, con una composición total de monómeros en peso que comprende unidades polimerizadas de 5 a 25 % en peso de ácido metacrílico y 75 a 95 % en peso de otros monómeros, en el que los monómeros adicionales se seleccionan entre alquilésteres C1 a C4 de ácido metacrílico y/o alquilésteres C1 a C4 de ácido acrílico, mediante polimerización en emulsión por etapas o en gradiente, en el que la relación en peso de unidades polimerizadas de ácido metacrílico a monómeros adicionales aumentan por etapas o en un gradiente desde el centro hasta la superficie de las partículas y en el que las partículas poliméricas se obtienen en forma de una dispersión acuosa.
MX2021006447A 2018-12-05 2019-11-11 Procedimiento de preparacion de particulas polimericas. MX2021006447A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18210330 2018-12-05
PCT/EP2019/080788 WO2020114714A1 (en) 2018-12-05 2019-11-11 Process for preparing polymeric particles

Publications (1)

Publication Number Publication Date
MX2021006447A true MX2021006447A (es) 2021-07-02

Family

ID=64959084

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021006447A MX2021006447A (es) 2018-12-05 2019-11-11 Procedimiento de preparacion de particulas polimericas.

Country Status (10)

Country Link
US (1) US20220054421A1 (es)
EP (1) EP3891191A1 (es)
JP (1) JP2022511855A (es)
KR (1) KR20210099064A (es)
CN (1) CN113166287B (es)
BR (1) BR112021010623A2 (es)
CA (1) CA3121333A1 (es)
IL (1) IL283618A (es)
MX (1) MX2021006447A (es)
WO (1) WO2020114714A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4366710A1 (en) 2021-07-09 2024-05-15 Evonik Operations GmbH Composition comprising a (meth)acrylate copolymer, an alkali or ammonium salt of a saturated aliphatic monocarboxylic acid and specific glidants

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE9414066U1 (de) * 1994-08-31 1994-11-03 Roehm Gmbh Überzugs- und Bindemittel für Arzneiformen sowie damit hergestellte Arzneiform
DE10260919A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug
DE102005007059A1 (de) * 2005-02-15 2006-08-24 Röhm GmbH & Co. KG Teilneutralisiertes anionisches (Meth)acrylat-Copolymer
CN101696277B (zh) * 2009-10-27 2011-09-28 华南理工大学 丙烯酸酯聚合物可再分散乳胶粉及其制备方法
ES2616006T3 (es) 2011-06-17 2017-06-09 Evonik Röhm Gmbh Composición de recubrimiento adecuada para formas farmacéuticas o nutracéuticas
CN103160051B (zh) * 2011-12-16 2015-12-02 北京化工大学 一种表面含叔胺基的聚合物颗粒作为热可逆反应性填料的用途及其组合物
BR102014017358B1 (pt) * 2013-07-30 2020-06-02 Rohm And Haas Company Dispersão aquosa estável de partículas de polímero, e, método
JP6824197B2 (ja) * 2015-06-05 2021-02-03 エボニック オペレーションズ ゲーエムベーハー エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物
FI128940B (en) * 2015-09-04 2021-03-31 Kemira Oyj Core / shell polymer particles as surface sizing agent
EP3248465A1 (en) * 2016-05-25 2017-11-29 Bayer CropScience Aktiengesellschaft Agrochemical formulation based on emulsion polymers

Also Published As

Publication number Publication date
US20220054421A1 (en) 2022-02-24
KR20210099064A (ko) 2021-08-11
CN113166287A (zh) 2021-07-23
CA3121333A1 (en) 2020-06-11
EP3891191A1 (en) 2021-10-13
IL283618A (en) 2021-07-29
BR112021010623A2 (pt) 2021-09-14
WO2020114714A1 (en) 2020-06-11
CN113166287B (zh) 2023-04-14
JP2022511855A (ja) 2022-02-01

Similar Documents

Publication Publication Date Title
BR112015028368A2 (pt) elastômeros termoplásticos por meio de polimerização de triglicerídeos por transferência de cadeia de fragmentação-adição reversível
HRP20170831T1 (hr) Upotreba polimerne disperzije kao agensa za kontrolu prašine
MX2017003650A (es) Polimeros de emulsion acuosa finamente divididos y su uso para recubrimientos hidrofobos.
BR112019003705A2 (pt) dispersões aquosas livres de flúor para o acabamento de tecidos têxteis
MX2016010843A (es) Composiciones de copolimero de etapa multiple para usarse en recubrimiento final de cuero.
MX2016017135A (es) Una dispersion de copolimero de (met) acrilato que contiene una unidad monomerica funcional de (met) acrilato de hidroxialquilo para materiales impermeabilizantes cementicios flexibles.
TR201902550T4 (tr) Oksazolin monomerler içeren kopolimer ve bunların çapraz bağ oluşturucu madde olarak kullanımı.
MX2017015465A (es) Composicion farmaceutica o nutraceutica con resistencia contra la influencia del etanol.
BR112018071658A2 (pt) processo para preparar um látex polimérico aquoso, látex polimérico aquoso, uso de um látex polimérico aquoso, composição de revestimento aquosa, e, dispersão aquosa.
PH12017502077A1 (en) Copolymers of bicyclic (meth)acrylates and alkyl (meth)acrylates and their use as rheology modifiers in fuels
WO2011155982A3 (en) Polymer polyols prepared from nitrile-free azo-initiators
PH12015500393A1 (en) Process for producing polymers
RU2018118366A (ru) Покрывающие композиции для покрытия волоконно-цементной плиты
NZ736149A (en) Durable anti-fingerprint polymers and coating compositions
MX2017006809A (es) Polimero multifasico como agente de espesamiento y suspension.
BR112017000044A2 (pt) método de preparação de copolímero zwitteriônico, solução de copolímero zwitteriônico, e composição de revestimento resistente a incrustações
MX2021006447A (es) Procedimiento de preparacion de particulas polimericas.
MX2017000625A (es) Adhesivos sensibles a la presion.
MX2018009807A (es) Proceso para la preparacion de microcapsulas.
MY191677A (en) Composition containing graphene and graphene nanoplatelets and preparation process thereof
MX2018006524A (es) Polimeros de emulsion y composiciones de recubrimiento con bajo contenido de voc fabricadas de los mismos.
MY172657A (en) Branched broad mwd conjugated diene polymer
FI3722341T3 (fi) Vinyyliasetaatin ja syklisen keteeniasetaalimonomeerin sekapolymeerihiukkasten vesidispersio
RU2017123625A (ru) Способ суспензионной полимеризации
MX2016006019A (es) Composiciones de catalizador y metodos para prepararlas.