MX2020013814A - Ensayo multiple proteomico mejorado. - Google Patents

Ensayo multiple proteomico mejorado.

Info

Publication number
MX2020013814A
MX2020013814A MX2020013814A MX2020013814A MX2020013814A MX 2020013814 A MX2020013814 A MX 2020013814A MX 2020013814 A MX2020013814 A MX 2020013814A MX 2020013814 A MX2020013814 A MX 2020013814A MX 2020013814 A MX2020013814 A MX 2020013814A
Authority
MX
Mexico
Prior art keywords
proteomic
improved
multiplex assays
methods
reagents
Prior art date
Application number
MX2020013814A
Other languages
English (en)
Inventor
Dominic Zichi
Stephan Kraemer
Evaldas Katilius
Original Assignee
Somalogic Operating Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Operating Co Inc filed Critical Somalogic Operating Co Inc
Publication of MX2020013814A publication Critical patent/MX2020013814A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La presente invención se refiere a métodos, dispositivos, reactivos y kits diseñados para mejorar el desempeño de ensayos de base proteómica. Tales métodos tienen una amplia utilidad en aplicaciones proteómicas para investigación y desarrollo, diagnósticos y terapéuticos proporcionando una reducción o eliminación de la señal antecedente y especificidad mejorada para reactivos de unión a proteína en formatos de ensayo multiplexos.
MX2020013814A 2018-06-22 2019-06-19 Ensayo multiple proteomico mejorado. MX2020013814A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862688770P 2018-06-22 2018-06-22
PCT/US2019/038022 WO2019246289A1 (en) 2018-06-22 2019-06-19 Improved proteomic multiplex assays

Publications (1)

Publication Number Publication Date
MX2020013814A true MX2020013814A (es) 2021-04-13

Family

ID=68983070

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2020013814A MX2020013814A (es) 2018-06-22 2019-06-19 Ensayo multiple proteomico mejorado.

Country Status (12)

Country Link
US (1) US20210247387A1 (es)
EP (1) EP3810563A4 (es)
JP (1) JP7526102B2 (es)
KR (1) KR20210034597A (es)
CN (1) CN112638845B (es)
AU (1) AU2019290130A1 (es)
BR (1) BR112020026129B1 (es)
CA (1) CA3104041A1 (es)
IL (1) IL279254A (es)
MX (1) MX2020013814A (es)
SG (1) SG11202012472TA (es)
WO (1) WO2019246289A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021076713A1 (en) * 2019-10-16 2021-04-22 Somalogic, Inc. Nucleic acid compounds that bind to retinoic acid-inducible gene i protein
US12064769B2 (en) 2021-12-22 2024-08-20 Somalogic Operating Co., Inc. Method for conducting uniform reactions

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL148515A0 (en) * 1999-09-16 2002-09-12 Solvay Pharm Bv Human g-protein coupled receptor
CN100558879C (zh) * 2002-10-03 2009-11-11 诺曼·利·安德森 用质谱法高灵敏度定量肽
EP1737899B1 (en) * 2004-04-20 2015-07-08 Dendritic Nanotechnologies, Inc. Dendritic polymers with enhanced amplification and interior functionality
JP4970260B2 (ja) * 2004-08-20 2012-07-04 プロメティック バイオサイエンシズ，リミテッド 親和性クロマトグラフィーによるタンパク質の逐次的単離および精製スキーム
AU2007205974A1 (en) * 2006-01-17 2007-07-26 Somalogic, Incorporated Multiplexed analyses of test samples
US20110136099A1 (en) * 2007-01-16 2011-06-09 Somalogic, Inc. Multiplexed Analyses of Test Samples
US7855054B2 (en) * 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
CN101809167B (zh) * 2007-07-17 2015-04-01 私募蛋白质体公司 产生具有改良的解离速率的适配体的方法
CA3011730C (en) * 2008-09-09 2022-05-17 Somalogic, Inc. Lung cancer biomarkers and uses thereof
GB2470939A (en) * 2009-06-10 2010-12-15 Dna Supernova Ltd Signal amplification microspheres
EP2558478B1 (en) * 2010-04-12 2018-03-07 Somalogic, Inc. 5-position modified pyrimidines and their use
EP2591357A4 (en) * 2010-07-09 2014-01-01 Somalogic Inc BIOMARKER FOR LUNG CANCER AND USE
WO2013055829A1 (en) * 2011-10-11 2013-04-18 Nestec S.A. Proximity-based assays for the detection of signaling protein expression and activation
MY170164A (en) * 2012-06-07 2019-07-09 Somalogic Inc Aptamer-based multiplexed assays
WO2014074682A1 (en) * 2012-11-07 2014-05-15 Somalogic, Inc. Chronic obstructive pulmonary disease (copd) biomarkers and uses thereof
WO2014093698A1 (en) * 2012-12-12 2014-06-19 The Methodist Hospital Research Institute Multi-aptamer-based, cell-specific, one-step tumor cell detection assays
JP6506768B2 (ja) * 2013-09-24 2019-04-24 ソマロジック・インコーポレーテッド 多重アプタマー標的の検出
US9587268B2 (en) * 2014-01-29 2017-03-07 Agilent Technologies Inc. Fast hybridization for next generation sequencing target enrichment
US20180259533A1 (en) * 2015-09-09 2018-09-13 Somalogic, Inc. Methods for developing personalized drug treatment plans and targeted drug development based on proteomic profiles

Also Published As

Publication number Publication date
BR112020026129A8 (pt) 2022-10-18
US20210247387A1 (en) 2021-08-12
AU2019290130A1 (en) 2021-01-28
CN112638845A (zh) 2021-04-09
BR112020026129B1 (pt) 2023-10-10
IL279254A (en) 2021-01-31
KR20210034597A (ko) 2021-03-30
WO2019246289A1 (en) 2019-12-26
JP2021528646A (ja) 2021-10-21
CN112638845B (zh) 2024-07-30
EP3810563A1 (en) 2021-04-28
EP3810563A4 (en) 2022-03-23
CA3104041A1 (en) 2019-12-26
SG11202012472TA (en) 2021-01-28
JP7526102B2 (ja) 2024-07-31
BR112020026129A2 (pt) 2021-03-16

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