BR112020026129A8 - Ensaios proteômicos multiplex melhorados - Google Patents

Ensaios proteômicos multiplex melhorados

Info

Publication number
BR112020026129A8
BR112020026129A8 BR112020026129A BR112020026129A BR112020026129A8 BR 112020026129 A8 BR112020026129 A8 BR 112020026129A8 BR 112020026129 A BR112020026129 A BR 112020026129A BR 112020026129 A BR112020026129 A BR 112020026129A BR 112020026129 A8 BR112020026129 A8 BR 112020026129A8
Authority
BR
Brazil
Prior art keywords
proteomic assays
methods
improved multiplex
proteomics
multiplex proteomic
Prior art date
Application number
BR112020026129A
Other languages
English (en)
Other versions
BR112020026129A2 (pt
BR112020026129B1 (pt
Inventor
Kraemer Stephan
Katilius Evaldas
Zichi Dominic
Original Assignee
Somalogic Inc
Somalogic Operating Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somalogic Inc, Somalogic Operating Co Inc filed Critical Somalogic Inc
Publication of BR112020026129A2 publication Critical patent/BR112020026129A2/pt
Publication of BR112020026129A8 publication Critical patent/BR112020026129A8/pt
Publication of BR112020026129B1 publication Critical patent/BR112020026129B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2570/00—Omics, e.g. proteomics, glycomics or lipidomics; Methods of analysis focusing on the entire complement of classes of biological molecules or subsets thereof, i.e. focusing on proteomes, glycomes or lipidomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Métodos, dispositivos, reagentes e kits projetados para melhorar o desempenho de ensaios baseados em proteômica são fornecidos. Tais métodos têm uma ampla utilidade em aplicações proteômicas para pesquisa e desenvolvimento, diagnósticos e terapêuticas, proporcionando uma redução ou eliminação do sinal de fundo e especificidade aprimorada para reagentes de ligação de proteínas em formatos de ensaio multiplex.
BR112020026129-7A 2018-06-22 2019-06-19 Métodos para melhorar o desempenho de ensaios proteômicos multiplex BR112020026129B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862688770P 2018-06-22 2018-06-22
US62/688,770 2018-06-22
PCT/US2019/038022 WO2019246289A1 (en) 2018-06-22 2019-06-19 Improved proteomic multiplex assays

Publications (3)

Publication Number Publication Date
BR112020026129A2 BR112020026129A2 (pt) 2021-03-16
BR112020026129A8 true BR112020026129A8 (pt) 2022-10-18
BR112020026129B1 BR112020026129B1 (pt) 2023-10-10

Family

ID=68983070

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112020026129-7A BR112020026129B1 (pt) 2018-06-22 2019-06-19 Métodos para melhorar o desempenho de ensaios proteômicos multiplex

Country Status (12)

Country Link
US (1) US20210247387A1 (pt)
EP (1) EP3810563A4 (pt)
JP (1) JP2021528646A (pt)
KR (1) KR20210034597A (pt)
CN (1) CN112638845A (pt)
AU (1) AU2019290130A1 (pt)
BR (1) BR112020026129B1 (pt)
CA (1) CA3104041A1 (pt)
IL (1) IL279254A (pt)
MX (1) MX2020013814A (pt)
SG (1) SG11202012472TA (pt)
WO (1) WO2019246289A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022552192A (ja) * 2019-10-16 2022-12-15 ソマロジック オペレーティング カンパニー インコーポレイテッド レチノイン酸誘導遺伝子ｉタンパク質に結合する核酸化合物

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101782581A (zh) * 2002-10-03 2010-07-21 诺曼·利·安德森 用质谱法高灵敏度定量肽
MXPA06012207A (es) * 2004-04-20 2007-02-13 Dendritic Nanotechnologies Inc Polimeros dendriticos con amplificacion mejorada y funcionalidad interior.
TWI507528B (zh) * 2006-01-17 2015-11-11 Somalogic Inc 測試樣品的多重分析方法
US7855054B2 (en) * 2007-01-16 2010-12-21 Somalogic, Inc. Multiplexed analyses of test samples
US20110136099A1 (en) * 2007-01-16 2011-06-09 Somalogic, Inc. Multiplexed Analyses of Test Samples
CN103627792A (zh) * 2007-07-17 2014-03-12 私募蛋白质体公司 检测样品的多元分析
CN104198709A (zh) * 2008-09-09 2014-12-10 私募蛋白质体公司 肺癌生物标记及其用途
GB2470939A (en) * 2009-06-10 2010-12-15 Dna Supernova Ltd Signal amplification microspheres
WO2011130195A1 (en) * 2010-04-12 2011-10-20 Somalogic, Inc. APTAMERS TO β-NGF AND THEIR USE IN TREATING β-NGF MEDIATED DISEASES AND DISORDERS
SG10201508656VA (en) * 2010-07-09 2015-11-27 Somalogic Inc Lung cancer biomarkers and uses thereof
WO2013055829A1 (en) * 2011-10-11 2013-04-18 Nestec S.A. Proximity-based assays for the detection of signaling protein expression and activation
NZ701824A (en) * 2012-06-07 2017-01-27 Somalogic Inc Aptamer-based multiplexed assays
CN104812913B (zh) * 2012-11-07 2019-03-15 私募蛋白质体公司 慢性阻塞性肺疾病(copd)生物标记及其用途
WO2014093698A1 (en) * 2012-12-12 2014-06-19 The Methodist Hospital Research Institute Multi-aptamer-based, cell-specific, one-step tumor cell detection assays
CN105555957A (zh) * 2013-09-24 2016-05-04 私募蛋白质体公司 多适配子靶标检测
US9587268B2 (en) * 2014-01-29 2017-03-07 Agilent Technologies Inc. Fast hybridization for next generation sequencing target enrichment
KR102604025B1 (ko) * 2015-09-09 2023-11-21 소마로직 오퍼레이팅 컴퍼니, 인코포레이티드 개인별 약물 치료 계획의 개발 방법 및 단백질체 프로파일을 기반으로 하는 표적 약물 개발 방법

Also Published As

Publication number Publication date
KR20210034597A (ko) 2021-03-30
EP3810563A1 (en) 2021-04-28
CA3104041A1 (en) 2019-12-26
WO2019246289A1 (en) 2019-12-26
AU2019290130A1 (en) 2021-01-28
JP2021528646A (ja) 2021-10-21
US20210247387A1 (en) 2021-08-12
EP3810563A4 (en) 2022-03-23
BR112020026129A2 (pt) 2021-03-16
MX2020013814A (es) 2021-04-13
IL279254A (en) 2021-01-31
BR112020026129B1 (pt) 2023-10-10
SG11202012472TA (en) 2021-01-28
CN112638845A (zh) 2021-04-09

Similar Documents

Publication Publication Date Title
EP4293126A3 (en) Analysis of multiple analytes using a single assay
WO2015017285A3 (en) Multiplex blocker beads for immunoassays
ZA202100676B (en) Anti-tigit antibody and uses thereof
WO2009052400A8 (en) Antibodies that bind to mammalian ngal and uses thereof
WO2009048530A3 (en) Highly multiplexed particle-based assays
NO20083268L (no) Antistoffer anvist til HER-3 og anvendelser derav
MX346499B (es) Dispositivos, metodos y kits de inmunocromatografia.
MX2016005834A (es) Ensayos para igfbp7 con mejor rendimiento en muestras biológicas.
BR112015022844A2 (pt) métodos para detecção de anticorpos para doadores específicos e sistemas para pratica destes
ZA202002415B (en) Detection of symmetrical dimethylarginine
HK1126274A1 (en) T cell assays t
WO2011142781A3 (en) Pore-limit electrophoresis (ple) microchannel assays
WO2007067983A3 (en) Sulfotyrosine specific antibodies and uses therefor
MX2008000282A (es) Anticuerpos monoclonales, lineas celulares de hibridomas, metodos y kits para la deteccion de fitasa.
BR112020026129A8 (pt) Ensaios proteômicos multiplex melhorados
GB0616929D0 (en) Antibodies, assays and hybridomas
MX2010008514A (es) Analisis para diagnosticar neumonia estreptococica.
HRP20041088A2 (en) Method for identifying and extracing endotoxin
WO2015184321A3 (en) Rare molecule detection
WO2021202542A3 (en) Methods of profiling translation rate
EP4253950A3 (en) Ce-western applications for antibody development
MX2020010714A (es) Metodos para cuantificar la il-33.
BR112017017719A2 (pt) imunoensaio homogêneo com compensação para sinal antecedente
BR112018013224A2 (pt) métodos para melhorar a qualidade de sêmen
MX2021014171A (es) Metodos para identificar y cuantificar proteinas de la celula huesped.

Legal Events

Date Code Title Description
B350 Update of information on the portal [chapter 15.35 patent gazette]
B25D Requested change of name of applicant approved

Owner name: SOMALOGIC OPERATING CO., INC. (US)

B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/06/2019, OBSERVADAS AS CONDICOES LEGAIS