MX2020002790A - Polimero y forma de dosis con propiedades de liberacion sostenida y resistencia contra la influencia de etanol. - Google Patents
Polimero y forma de dosis con propiedades de liberacion sostenida y resistencia contra la influencia de etanol.Info
- Publication number
- MX2020002790A MX2020002790A MX2020002790A MX2020002790A MX2020002790A MX 2020002790 A MX2020002790 A MX 2020002790A MX 2020002790 A MX2020002790 A MX 2020002790A MX 2020002790 A MX2020002790 A MX 2020002790A MX 2020002790 A MX2020002790 A MX 2020002790A
- Authority
- MX
- Mexico
- Prior art keywords
- sub
- polymer
- dosage form
- ethanol
- influence
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/38—Polymerisation using regulators, e.g. chain terminating agents, e.g. telomerisation
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/12—Esters of monohydric alcohols or phenols
- C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
- C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
- C08F220/1808—C8-(meth)acrylate, e.g. isooctyl (meth)acrylate or 2-ethylhexyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/20—Esters of polyhydric alcohols or phenols, e.g. 2-hydroxyethyl (meth)acrylate or glycerol mono-(meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
- C09D133/10—Homopolymers or copolymers of methacrylic acid esters
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/34—Esters containing nitrogen, e.g. N,N-dimethylaminoethyl (meth)acrylate
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
- C09D133/062—Copolymers with monomers not covered by C09D133/06
- C09D133/066—Copolymers with monomers not covered by C09D133/06 containing -OH groups
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D133/00—Coating compositions based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Coating compositions based on derivatives of such polymers
- C09D133/04—Homopolymers or copolymers of esters
- C09D133/14—Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
Abstract
La invención se refiere a un polímero, polimerizado a partir de una mezcla de monómeros que comprende (a) de 70 a 95% en peso de metacrilato de 2-etilhexilo (EHMA) y metacrilato de etilo (EMA) o metacrilato de 2- etilhexilo (EHMA) y metacrilato de metilo (MMA), (b) de 2.5 a 25% en peso de uno o ésteres hidroxialquílicos de C2 a C6 de ácido acrílico o ácido metacrílico, (c) de 2.5 a 15% en peso de uno o más ésteres alquílicos de C2 a C8 de ácido acrílico o de ácido metacrílico con un grupo catiónico cuaternario en el grupo alquilo. También se describe el uso de un polímero para preparar una forma de dosis con un perfil de liberación sostenida y resistencia contra la influencia de etanol y la forma de dosificación por sí sola.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17191129 | 2017-09-14 | ||
EP2018055856 | 2018-03-09 | ||
PCT/EP2018/073652 WO2019052845A1 (en) | 2017-09-14 | 2018-09-04 | POLYMER AND PHARMACEUTICAL FORM WITH PROLONGED RELEASE PROPERTIES AND RESISTANCE TO THE INFLUENCE OF ETHANOL |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2020002790A true MX2020002790A (es) | 2020-08-20 |
Family
ID=63371711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2020002790A MX2020002790A (es) | 2017-09-14 | 2018-09-04 | Polimero y forma de dosis con propiedades de liberacion sostenida y resistencia contra la influencia de etanol. |
Country Status (14)
Country | Link |
---|---|
US (1) | US20200289423A1 (es) |
EP (1) | EP3681918B1 (es) |
JP (1) | JP2020533468A (es) |
KR (1) | KR20200057019A (es) |
CN (1) | CN111356709A (es) |
BR (1) | BR112020004997A2 (es) |
CA (1) | CA3075204A1 (es) |
ES (1) | ES2909605T3 (es) |
HU (1) | HUE057718T2 (es) |
IL (1) | IL273197A (es) |
MX (1) | MX2020002790A (es) |
PL (1) | PL3681918T3 (es) |
SI (1) | SI3681918T1 (es) |
WO (1) | WO2019052845A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX2021010914A (es) * | 2019-03-11 | 2021-10-01 | Evonik Operations Gmbh | Forma de dosificacion que comprende una matriz polimerica. |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3438291A1 (de) | 1984-10-19 | 1986-04-24 | Röhm GmbH, 6100 Darmstadt | Verfahren zur herstellung einer waessrigen ueberzugsmitteldispersion und ihre verwendung zum ueberziehen von arzneimitteln |
JPS61152757A (ja) * | 1984-12-26 | 1986-07-11 | Dainippon Toryo Co Ltd | カチオン性水性分散体及びその製造方法 |
WO2009036811A1 (en) | 2007-09-21 | 2009-03-26 | Evonik Röhm Gmbh | Ph-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol |
US9700520B2 (en) | 2007-09-21 | 2017-07-11 | Evonik Roehm Gmbh | PH-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
EP2341899B1 (en) | 2008-09-24 | 2014-12-17 | Evonik Röhm GmbH | Ph-dependent controlled release pharmaceutical opioid composition with resistance against the influence of ethanol |
US10933024B2 (en) | 2008-09-24 | 2021-03-02 | Evonik Operations Gmbh | PH-dependent controlled release pharmaceutical composition for non-opioids with resistance against the influence of ethanol |
BRPI0924427A2 (pt) | 2009-03-18 | 2016-01-26 | Evonik Roehm Gmbh | composição farmacêutica de liberação controlada, seu processo de preparação e uso da mesma |
MX2011009667A (es) | 2009-03-18 | 2011-12-14 | Evonik Roehm Gmbh | Composición farmacéutica de liberación controlada con resistencia a la influencia de etanol mediante el uso de un revestimiento compuesto de polímeros de vinilo neutrales y excipientes. |
US9775815B2 (en) | 2011-06-17 | 2017-10-03 | Evonik Roehm Gmbh | Gastric resistant pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
KR102004436B1 (ko) | 2011-11-30 | 2019-07-26 | 토요잉크Sc홀딩스주식회사 | 컬러 필터용 착색 조성물, 및 컬러 필터 |
WO2014151797A1 (en) | 2013-03-15 | 2014-09-25 | Mylan, Inc. | Extended release formulations resistant to alcohol dose dumping |
US9895318B2 (en) | 2014-02-17 | 2018-02-20 | Evonik Roehm Gmbh | Pharmaceutical or nutraceutical composition with sustained release characteristic and with resistance against the influence of ethanol |
JP6695337B2 (ja) * | 2014-11-26 | 2020-05-20 | レーム・ゲーエムベーハーRoehm GmbH | エタノールの影響に対する耐性を有する医薬品組成物または栄養機能食品組成物 |
JP6511898B2 (ja) | 2015-03-24 | 2019-05-15 | 東洋インキScホールディングス株式会社 | 固体撮像素子用感光性着色組成物、固体撮像素子用カラーフィルタ、及び固体撮像素子 |
US10980751B2 (en) | 2015-06-05 | 2021-04-20 | Evonik Operations Gmbh | Pharmaceutical or nutraceutical composition with resistance against the influence of ethanol |
-
2018
- 2018-09-04 EP EP18759647.3A patent/EP3681918B1/en active Active
- 2018-09-04 KR KR1020207010249A patent/KR20200057019A/ko not_active Application Discontinuation
- 2018-09-04 BR BR112020004997-2A patent/BR112020004997A2/pt not_active Application Discontinuation
- 2018-09-04 JP JP2020515122A patent/JP2020533468A/ja active Pending
- 2018-09-04 CN CN201880070004.3A patent/CN111356709A/zh active Pending
- 2018-09-04 CA CA3075204A patent/CA3075204A1/en not_active Abandoned
- 2018-09-04 US US16/646,466 patent/US20200289423A1/en not_active Abandoned
- 2018-09-04 ES ES18759647T patent/ES2909605T3/es active Active
- 2018-09-04 PL PL18759647T patent/PL3681918T3/pl unknown
- 2018-09-04 WO PCT/EP2018/073652 patent/WO2019052845A1/en unknown
- 2018-09-04 MX MX2020002790A patent/MX2020002790A/es unknown
- 2018-09-04 SI SI201830573T patent/SI3681918T1/sl unknown
- 2018-09-04 HU HUE18759647A patent/HUE057718T2/hu unknown
-
2020
- 2020-03-10 IL IL273197A patent/IL273197A/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES2909605T3 (es) | 2022-05-09 |
KR20200057019A (ko) | 2020-05-25 |
BR112020004997A2 (pt) | 2020-09-24 |
IL273197A (en) | 2020-04-30 |
EP3681918A1 (en) | 2020-07-22 |
CA3075204A1 (en) | 2019-03-21 |
EP3681918B1 (en) | 2022-01-12 |
WO2019052845A1 (en) | 2019-03-21 |
JP2020533468A (ja) | 2020-11-19 |
US20200289423A1 (en) | 2020-09-17 |
HUE057718T2 (hu) | 2022-06-28 |
CN111356709A (zh) | 2020-06-30 |
SI3681918T1 (sl) | 2022-04-29 |
PL3681918T3 (pl) | 2022-04-19 |
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