MX2019006614A - Adnc del antagonista del receptor de interleucina-1. - Google Patents

Adnc del antagonista del receptor de interleucina-1.

Info

Publication number
MX2019006614A
MX2019006614A MX2019006614A MX2019006614A MX2019006614A MX 2019006614 A MX2019006614 A MX 2019006614A MX 2019006614 A MX2019006614 A MX 2019006614A MX 2019006614 A MX2019006614 A MX 2019006614A MX 2019006614 A MX2019006614 A MX 2019006614A
Authority
MX
Mexico
Prior art keywords
cdnas
osteoarthritis
codon
intra
compositions
Prior art date
Application number
MX2019006614A
Other languages
English (en)
Inventor
C Ghivizzani Steven
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=62491596&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2019006614(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Florida filed Critical Univ Florida
Publication of MX2019006614A publication Critical patent/MX2019006614A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)

Abstract

La presente descripción se refiere a composiciones y métodos para el tratamiento de afecciones degenerativas de grandes articulaciones que soportan peso, tales como osteoartritis, mediante administración intra-articular de un gen que codifica IL-1Ra modificado por codón.
MX2019006614A 2016-12-07 2017-12-07 Adnc del antagonista del receptor de interleucina-1. MX2019006614A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662431336P 2016-12-07 2016-12-07
US201762486944P 2017-04-18 2017-04-18
PCT/US2017/065173 WO2018106956A2 (en) 2016-12-07 2017-12-07 IL-1RA CDNAs

Publications (1)

Publication Number Publication Date
MX2019006614A true MX2019006614A (es) 2019-10-15

Family

ID=62491596

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019006614A MX2019006614A (es) 2016-12-07 2017-12-07 Adnc del antagonista del receptor de interleucina-1.

Country Status (10)

Country Link
US (2) US11958886B2 (es)
EP (1) EP3551650A4 (es)
JP (2) JP7282378B2 (es)
KR (1) KR20190088561A (es)
CN (1) CN110225923A (es)
AU (2) AU2017371043B2 (es)
BR (1) BR112019011592A2 (es)
CA (1) CA3046347A1 (es)
MX (1) MX2019006614A (es)
WO (1) WO2018106956A2 (es)

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KR20230130155A (ko) 2016-08-19 2023-09-11 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 재조합 자기-상보적인 아데노-부속 바이러스를 이용한 병태의 치료 방법 및 조성물
WO2018106956A2 (en) 2016-12-07 2018-06-14 University Of Florida Research Foundation, Incorporated IL-1RA CDNAs
CN110938642B (zh) * 2018-09-25 2023-08-29 上海恒润达生生物科技股份有限公司 靶向CD123-BBz-IL1RN的嵌合抗原受体
US20220016213A1 (en) * 2018-11-28 2022-01-20 Genascence Corporation Methods and Compositions for Treating Osteoarthritis
AU2020314883A1 (en) * 2019-07-15 2022-03-03 Meiragtx Uk Ii Limited Modified AAV capsid proteins for treatment of arthritic disease
WO2024029331A1 (ja) * 2022-07-30 2024-02-08 国立大学法人 東京医科歯科大学 関節疾患の治療及び／又は予防に用いるための医薬組成物
CN117860892B (zh) * 2023-12-26 2024-08-06 武汉大学中南医院 Il-16阳性神经元在调节恐惧消退记忆中的作用

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Also Published As

Publication number Publication date
JP7282378B2 (ja) 2023-05-29
BR112019011592A2 (pt) 2019-10-22
US20240327479A1 (en) 2024-10-03
US11958886B2 (en) 2024-04-16
US20200071371A1 (en) 2020-03-05
KR20190088561A (ko) 2019-07-26
EP3551650A2 (en) 2019-10-16
JP2023078402A (ja) 2023-06-06
JP2019536465A (ja) 2019-12-19
CN110225923A (zh) 2019-09-10
AU2023201531A1 (en) 2023-04-13
WO2018106956A3 (en) 2018-07-12
AU2017371043A1 (en) 2019-07-11
CA3046347A1 (en) 2018-06-14
AU2017371043B2 (en) 2022-12-15
EP3551650A4 (en) 2020-07-08
WO2018106956A2 (en) 2018-06-14

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