MX2019004116A - Metodo de preparacion de peptidos que comprenden una cadena lateral de lisina modificada lipofilicamente. - Google Patents
Metodo de preparacion de peptidos que comprenden una cadena lateral de lisina modificada lipofilicamente.Info
- Publication number
- MX2019004116A MX2019004116A MX2019004116A MX2019004116A MX2019004116A MX 2019004116 A MX2019004116 A MX 2019004116A MX 2019004116 A MX2019004116 A MX 2019004116A MX 2019004116 A MX2019004116 A MX 2019004116A MX 2019004116 A MX2019004116 A MX 2019004116A
- Authority
- MX
- Mexico
- Prior art keywords
- side chain
- lysine side
- modified lysine
- preparing peptides
- lipophilically modified
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/006—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length of peptides containing derivatised side chain amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57563—Vasoactive intestinal peptide [VIP]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16306332 | 2016-10-10 | ||
| PCT/EP2017/075773 WO2018069295A1 (en) | 2016-10-10 | 2017-10-10 | Method of preparing peptides comprising a lipophilically modified lysine side chain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2019004116A true MX2019004116A (es) | 2019-08-12 |
Family
ID=57153433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2019004116A MX2019004116A (es) | 2016-10-10 | 2017-10-10 | Metodo de preparacion de peptidos que comprenden una cadena lateral de lisina modificada lipofilicamente. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US11021512B2 (zh) |
| EP (1) | EP3523324B1 (zh) |
| JP (1) | JP2019533666A (zh) |
| KR (1) | KR20190059321A (zh) |
| CN (1) | CN109790208A (zh) |
| AR (1) | AR109914A1 (zh) |
| AU (1) | AU2017341951B2 (zh) |
| BR (1) | BR112019007063A2 (zh) |
| CA (1) | CA3039752A1 (zh) |
| IL (1) | IL265888A (zh) |
| MX (1) | MX2019004116A (zh) |
| RU (1) | RU2755543C2 (zh) |
| SG (1) | SG11201903100TA (zh) |
| TW (1) | TW201821434A (zh) |
| WO (1) | WO2018069295A1 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11028123B2 (en) | 2018-04-10 | 2021-06-08 | Sanofi-Aventis Deutschland Gmbh | Capping of unprotected amino groups during peptide synthesis |
| JP7434169B2 (ja) | 2018-04-10 | 2024-02-20 | サノフィ－アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 固相からの固相結合ペプチドの切断方法 |
| CN110183531A (zh) * | 2019-05-17 | 2019-08-30 | 河北常山生化药业股份有限公司 | 一种艾本那肽前体的制备方法 |
| CN111704654B (zh) * | 2020-06-18 | 2021-12-03 | 上海交通大学医学院附属仁济医院 | 肽类化合物及其制备方法与应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090318353A1 (en) * | 2006-08-25 | 2009-12-24 | Novo Nordisk A/S | Acylated Exendin-4 Compounds |
| KR101939557B1 (ko) | 2008-10-17 | 2019-01-17 | 사노피-아벤티스 도이칠란트 게엠베하 | 인슐린과 ｇｌｐ－1 효능제의 병용물 |
| CN101987868B (zh) * | 2009-07-30 | 2013-09-04 | 江苏豪森医药集团有限公司 | Glp-1类似物的衍生物或其可药用盐和用途 |
| US8614182B2 (en) * | 2009-07-30 | 2013-12-24 | Jiangsu Hansoh Pharmaceuticals Co., Ltd. | GLP-1 analogues and their pharmaceutical salts and uses |
| PT3345593T (pt) | 2009-11-13 | 2023-11-27 | Sanofi Aventis Deutschland | Composição farmacêutica compreendendo despro36exendina- 4(1-39)-lys6-nh2 e metionina |
| FR2952695B1 (fr) | 2009-11-13 | 2012-03-30 | Commissariat Energie Atomique | Reservoir de stockage d'hydrogene a hydrures metalliques |
| WO2011104378A1 (en) | 2010-02-26 | 2011-09-01 | Novo Nordisk A/S | Peptides for treatment of obesity |
| CA2797133C (en) * | 2010-04-27 | 2019-08-06 | Zealand Pharma A/S | Peptide conjugates of glp-1 receptor agonists and gastrin and their use |
| CN104519902B (zh) * | 2012-05-08 | 2017-10-27 | 诺和诺德股份有限公司 | 双酰化glp‑1衍生物 |
| SG11201407860PA (en) | 2012-06-14 | 2014-12-30 | Sanofi Sa | Exendin-4 peptide analogues |
| UA116217C2 (uk) * | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| MA38276B1 (fr) | 2012-12-21 | 2018-03-30 | Sanofi Sa | Dérivés de l'exendine 4 pour l’utilisation dans le traitement des troubles du syndrome metabolique, y compris le diabete et l'obesite, ainsi que la reduction de l'apport alimentaire excessif. |
| TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽－４（Ｅｘｅｎｄｉｎ－４）之肽類雙重ＧＬＰ－１／升糖素受體促效劑 |
| TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重ｇｌｐ－１／昇糖素受體激動劑之艾塞那肽－４衍生物 |
| TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自ｅｘｅｎｄｉｎ－４之雙重ｇｌｐ－１／升糖素受體促效劑 |
-
2017
- 2017-10-06 TW TW106134587A patent/TW201821434A/zh unknown
- 2017-10-10 SG SG11201903100TA patent/SG11201903100TA/en unknown
- 2017-10-10 AR ARP170102825A patent/AR109914A1/es unknown
- 2017-10-10 MX MX2019004116A patent/MX2019004116A/es unknown
- 2017-10-10 CN CN201780062214.3A patent/CN109790208A/zh active Pending
- 2017-10-10 CA CA3039752A patent/CA3039752A1/en not_active Abandoned
- 2017-10-10 US US16/338,213 patent/US11021512B2/en active Active
- 2017-10-10 JP JP2019519255A patent/JP2019533666A/ja active Pending
- 2017-10-10 BR BR112019007063A patent/BR112019007063A2/pt not_active Application Discontinuation
- 2017-10-10 KR KR1020197013154A patent/KR20190059321A/ko not_active Application Discontinuation
- 2017-10-10 EP EP17787900.4A patent/EP3523324B1/en active Active
- 2017-10-10 WO PCT/EP2017/075773 patent/WO2018069295A1/en active Application Filing
- 2017-10-10 AU AU2017341951A patent/AU2017341951B2/en not_active Expired - Fee Related
- 2017-10-10 RU RU2019113729A patent/RU2755543C2/ru active
-
2019
- 2019-04-07 IL IL265888A patent/IL265888A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2017341951B2 (en) | 2021-08-05 |
| AR109914A1 (es) | 2019-02-06 |
| KR20190059321A (ko) | 2019-05-30 |
| BR112019007063A2 (pt) | 2019-11-26 |
| US20200024304A1 (en) | 2020-01-23 |
| CA3039752A1 (en) | 2018-04-19 |
| AU2017341951A1 (en) | 2019-05-30 |
| TW201821434A (zh) | 2018-06-16 |
| EP3523324B1 (en) | 2021-09-22 |
| WO2018069295A1 (en) | 2018-04-19 |
| IL265888A (en) | 2019-06-30 |
| US11021512B2 (en) | 2021-06-01 |
| JP2019533666A (ja) | 2019-11-21 |
| RU2019113729A (ru) | 2020-11-13 |
| CN109790208A (zh) | 2019-05-21 |
| SG11201903100TA (en) | 2019-05-30 |
| RU2755543C2 (ru) | 2021-09-17 |
| EP3523324A1 (en) | 2019-08-14 |
| RU2019113729A3 (zh) | 2021-02-20 |
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