MX2018013268A - Sistema de jeringa precargada con toxina botulinica. - Google Patents
Sistema de jeringa precargada con toxina botulinica.Info
- Publication number
- MX2018013268A MX2018013268A MX2018013268A MX2018013268A MX2018013268A MX 2018013268 A MX2018013268 A MX 2018013268A MX 2018013268 A MX2018013268 A MX 2018013268A MX 2018013268 A MX2018013268 A MX 2018013268A MX 2018013268 A MX2018013268 A MX 2018013268A
- Authority
- MX
- Mexico
- Prior art keywords
- botulinum toxin
- prefilled syringe
- syringe system
- toxin prefilled
- force
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31511—Piston or piston-rod constructions, e.g. connection of piston with piston-rod
- A61M5/31513—Piston constructions to improve sealing or sliding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/48—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for varying, regulating, indicating or limiting injection pressure
- A61M5/488—Limiting injection pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3104—Caps for syringes without needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
- A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
- A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M2005/3151—Means for blocking or restricting the movement of the rod or piston by friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0468—Liquids non-physiological
- A61M2202/049—Toxic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/07—Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0222—Materials for reducing friction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/02—General characteristics of the apparatus characterised by a particular materials
- A61M2205/0238—General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a un sistema de jeringa precargada con toxina botulínica con características de fuerza de inyección deseables, en particular baja fuerza de deslizamiento y baja fuerza axial, que comprende un barril de jeringa de vidrio que contiene una composición de toxina botulínica líquida, un tapón de émbolo y un dispositivo de cierre tal como un tapa de punta o un protector de aguja. Además, la presente invención se relaciona con un kit que comprende el sistema de jeringa precargada con toxina botulínica y opcionalmente instrucciones de uso y con el uso del sistema de jeringa precargada con toxina botulínica en aplicaciones terapéuticas y cosméticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16001404 | 2016-06-22 | ||
PCT/EP2017/065050 WO2017220553A1 (en) | 2016-06-22 | 2017-06-20 | Botulinum toxin prefilled syringe system |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2018013268A true MX2018013268A (es) | 2019-01-30 |
Family
ID=56203079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2018013268A MX2018013268A (es) | 2016-06-22 | 2017-06-20 | Sistema de jeringa precargada con toxina botulinica. |
Country Status (13)
Country | Link |
---|---|
US (2) | US11331434B2 (es) |
EP (1) | EP3474931A1 (es) |
JP (2) | JP7301539B2 (es) |
KR (1) | KR102397053B1 (es) |
CN (1) | CN109069755B (es) |
AU (1) | AU2017281155B2 (es) |
CA (1) | CA3020897A1 (es) |
IL (1) | IL262612B (es) |
MX (1) | MX2018013268A (es) |
RU (1) | RU2745739C9 (es) |
SG (1) | SG11201808753WA (es) |
TW (1) | TWI737742B (es) |
WO (1) | WO2017220553A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI669129B (zh) | 2014-12-23 | 2019-08-21 | 德商梅茲製藥有限兩合公司 | 預填充式玻璃容器及其套組與使用 |
CN107206175B (zh) * | 2015-02-03 | 2021-06-01 | 莫茨制药有限及两合公司 | 肉毒杆菌毒素预填充式容器 |
JP7217700B2 (ja) | 2016-09-13 | 2023-02-03 | アラーガン、インコーポレイテッド | 安定化非タンパク質クロストリジウム毒素組成物 |
US11890456B2 (en) | 2016-11-16 | 2024-02-06 | DJ Medical, LLC | Self-administered injection device and method |
US10682308B2 (en) * | 2018-03-13 | 2020-06-16 | Nevakar Inc. | Succinylcholine prefilled syringe, compositions and methods |
DE102018122001A1 (de) | 2018-09-10 | 2020-03-12 | Schott Ag | Packmittel mit Gleitschicht und Verfahren für pharmazeutische und kosmetische Stoffe und Zubereitung zu dessen Herstellung |
FR3093004B1 (fr) * | 2019-02-21 | 2023-04-07 | Dev Techniques Plastiques | Procede de preparation d’une seringue |
JP2022521237A (ja) | 2019-02-21 | 2022-04-06 | メルツ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト アウフ アクティーン | 振戦治療のためのボツリヌス神経毒素の新規用途 |
BR112021015970A2 (pt) * | 2019-03-15 | 2021-10-05 | Chiesi Farmaceutici S.P.A. | Sistema que compreende uma seringa pré-carregável e uma embalagem para a seringa pré-carregável |
WO2021146356A1 (en) | 2020-01-13 | 2021-07-22 | DJ Medical, LLC | Injection device, system, and method for use |
KR102404217B1 (ko) * | 2020-04-08 | 2022-06-02 | (주)메디톡스 | 토출 속도 조절이 용이하고 안정한 보툴리눔 독소 사전충전된 주사기 제형 |
WO2021206360A1 (ko) * | 2020-04-08 | 2021-10-14 | (주)메디톡스 | 토출 속도 조절이 용이하고 안정한 보툴리눔 독소 사전충전된 주사기 제형 |
CN112546350B (zh) * | 2020-12-11 | 2022-05-24 | 郑州工业应用技术学院 | 一种远程医疗用流体注射设备 |
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JPS5918427B2 (ja) * | 1979-10-09 | 1984-04-27 | テルモ株式会社 | シリンジ用ガスケツト |
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US6213985B1 (en) * | 2000-06-06 | 2001-04-10 | Bracco Diagnostics, Inc. | Tapered syringe barrel with tapered plunger |
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JP2006519070A (ja) | 2003-02-27 | 2006-08-24 | バクスター・インターナショナル・インコーポレイテッド | 注射器のためのピストンアセンブリ |
DE102004043009A1 (de) | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
DE102005019302A1 (de) | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
JP2007195742A (ja) * | 2006-01-26 | 2007-08-09 | Daikyo Seiko Ltd | 流動食などの経口薬剤供給装置 |
EP1834962A1 (de) | 2006-03-15 | 2007-09-19 | Biotecon Therapeutics GmbH | PEGyliertes mutiertes Clostridium botulinum Toxin |
US20100167231A1 (en) * | 2006-11-24 | 2010-07-01 | Dubbe John W | Piston and handheld dispenser including a piston |
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CN101249291B (zh) * | 2008-02-04 | 2010-06-09 | 房东森 | 安全注射器 |
PL2271670T3 (pl) | 2008-03-14 | 2015-05-29 | Allergan Inc | Testy aktywności serotypu A toksyny botulinowej oparte na immunologii |
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EP3064240B1 (en) * | 2013-11-03 | 2020-11-25 | Terumo Kabushiki Kaisha | Needle-equipped sysringe, pre-filled syringe, and medical liquid administration device using same |
JP6270266B2 (ja) * | 2014-02-19 | 2018-01-31 | 住友ゴム工業株式会社 | プレフィルドシリンジ用ガスケットおよびプレフィルドシリンジ |
NZ729991A (en) | 2014-09-10 | 2020-02-28 | Sio2 Medical Products Inc | Three-position plungers, film coated plungers and related syringe assemblies |
CN107206175B (zh) * | 2015-02-03 | 2021-06-01 | 莫茨制药有限及两合公司 | 肉毒杆菌毒素预填充式容器 |
CN104759005B (zh) * | 2015-04-21 | 2017-07-11 | 山东淄博山川医用器材有限公司 | 低阻力注射器活塞及注射器 |
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2017
- 2017-06-02 TW TW106118350A patent/TWI737742B/zh active
- 2017-06-20 SG SG11201808753WA patent/SG11201808753WA/en unknown
- 2017-06-20 CA CA3020897A patent/CA3020897A1/en active Pending
- 2017-06-20 IL IL262612A patent/IL262612B/en unknown
- 2017-06-20 MX MX2018013268A patent/MX2018013268A/es unknown
- 2017-06-20 CN CN201780025400.XA patent/CN109069755B/zh active Active
- 2017-06-20 US US16/311,728 patent/US11331434B2/en active Active
- 2017-06-20 WO PCT/EP2017/065050 patent/WO2017220553A1/en unknown
- 2017-06-20 KR KR1020187031122A patent/KR102397053B1/ko active IP Right Grant
- 2017-06-20 AU AU2017281155A patent/AU2017281155B2/en active Active
- 2017-06-20 RU RU2018133772A patent/RU2745739C9/ru active
- 2017-06-20 EP EP17733769.8A patent/EP3474931A1/en active Pending
- 2017-06-20 JP JP2018555714A patent/JP7301539B2/ja active Active
-
2022
- 2022-03-24 JP JP2022049021A patent/JP2022088501A/ja active Pending
- 2022-04-08 US US17/716,603 patent/US20220273884A1/en active Pending
Also Published As
Publication number | Publication date |
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KR102397053B1 (ko) | 2022-05-12 |
IL262612B (en) | 2022-08-01 |
RU2018133772A (ru) | 2020-07-22 |
CN109069755A (zh) | 2018-12-21 |
IL262612A (en) | 2018-12-31 |
RU2745739C2 (ru) | 2021-03-31 |
SG11201808753WA (en) | 2019-01-30 |
TW201822826A (zh) | 2018-07-01 |
EP3474931A1 (en) | 2019-05-01 |
RU2745739C9 (ru) | 2021-12-14 |
RU2018133772A3 (es) | 2020-09-30 |
CN109069755B (zh) | 2022-04-19 |
US20220273884A1 (en) | 2022-09-01 |
KR20190022460A (ko) | 2019-03-06 |
WO2017220553A1 (en) | 2017-12-28 |
JP2019518500A (ja) | 2019-07-04 |
TWI737742B (zh) | 2021-09-01 |
JP2022088501A (ja) | 2022-06-14 |
AU2017281155B2 (en) | 2021-12-23 |
BR112018072085A2 (pt) | 2019-02-19 |
AU2017281155A1 (en) | 2018-10-25 |
JP7301539B2 (ja) | 2023-07-03 |
US20190201630A1 (en) | 2019-07-04 |
CA3020897A1 (en) | 2017-12-28 |
US11331434B2 (en) | 2022-05-17 |
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