MX2017009380A - Recipiente precargado con toxina botulinica. - Google Patents

Recipiente precargado con toxina botulinica.

Info

Publication number
MX2017009380A
MX2017009380A MX2017009380A MX2017009380A MX2017009380A MX 2017009380 A MX2017009380 A MX 2017009380A MX 2017009380 A MX2017009380 A MX 2017009380A MX 2017009380 A MX2017009380 A MX 2017009380A MX 2017009380 A MX2017009380 A MX 2017009380A
Authority
MX
Mexico
Prior art keywords
botulinum toxin
plastic container
prefilled container
toxin prefilled
prefilled
Prior art date
Application number
MX2017009380A
Other languages
English (en)
Inventor
Vogt Markus
Original Assignee
Merz Pharma Gmbh & Co Kgaa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merz Pharma Gmbh & Co Kgaa filed Critical Merz Pharma Gmbh & Co Kgaa
Publication of MX2017009380A publication Critical patent/MX2017009380A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/06Ampoules or carpules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893Botulinum neurotoxin (3.4.24.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66Enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • A61M5/31513Piston constructions to improve sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202Devices for protection of the needle before use, e.g. caps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24Metalloendopeptidases (3.4.24)
    • C12Y304/24069Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/87Application Devices; Containers; Packaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/91Injection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • A61M2005/3131Syringe barrels specially adapted for improving sealing or sliding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0216Materials providing elastic properties, e.g. for facilitating deformation and avoid breaking
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222Materials for reducing friction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0238General characteristics of the apparatus characterised by a particular materials the material being a coating or protective layer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)

Abstract

La presente invención se relaciona con un recipiente de plástico precargado, tal como una jeringa de plástico, que comprende una formulación de toxina botulínica acuosa. La formulación de toxina botulínica acuosa en el recipiente de plástico precargado es estable por un período más largo de tiempo. Además, la presente invención se relaciona con un kit que comprende el recipiente de plástico precargado, y al uso de un recipiente de plástico precargado para fines terapéuticos y cosméticos.
MX2017009380A 2015-02-03 2015-12-22 Recipiente precargado con toxina botulinica. MX2017009380A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15000310 2015-02-03
PCT/EP2015/002600 WO2016124213A1 (en) 2015-02-03 2015-12-22 Botulinum toxin prefilled container

Publications (1)

Publication Number Publication Date
MX2017009380A true MX2017009380A (es) 2018-01-09

Family

ID=52449922

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017009380A MX2017009380A (es) 2015-02-03 2015-12-22 Recipiente precargado con toxina botulinica.

Country Status (15)

Country Link
US (3) US10406290B2 (es)
EP (1) EP3253364A1 (es)
JP (2) JP6813492B2 (es)
KR (1) KR102627068B1 (es)
CN (1) CN107206175B (es)
AR (1) AR103244A1 (es)
AU (1) AU2015381351B2 (es)
BR (1) BR112017016759B1 (es)
CA (1) CA2974450C (es)
IL (1) IL253429B (es)
MX (1) MX2017009380A (es)
RU (1) RU2722290C2 (es)
SG (1) SG11201706247VA (es)
TW (1) TWI728964B (es)
WO (1) WO2016124213A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9314416B2 (en) * 2005-03-03 2016-04-19 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
US10792344B2 (en) * 2006-06-29 2020-10-06 Merz Pharma Gmbh & Co. Kgaa High frequency application of botulinum toxin therapy
KR102557798B1 (ko) * 2014-12-23 2023-07-19 메르츠 파마 게엠베하 운트 코. 카가아 보툴리눔 독소 사전충전된 용기
TWI728964B (zh) 2015-02-03 2021-06-01 德商梅茲製藥有限兩合公司 預填充式塑膠注射器及其套組與使用
TWI737742B (zh) 2016-06-22 2021-09-01 德商梅茲製藥有限兩合公司 肉毒桿菌毒素的預填充式注射器系統、具有其之套組以及其之使用
JP2022514151A (ja) * 2018-10-08 2022-02-10 メルツ ファルマ ゲーエムベーハー ウント コンパニー カーゲーアーアー 神経毒プレフィルドバイアル
SI3659594T1 (sl) * 2018-11-30 2021-02-26 Klaus Stegemann Sterilna raztopina z aplikacijskim injektorjem, ki vsebuje medicinsko sredstvo in postopek z proizvodnjo le-te
CN113573727A (zh) 2019-02-21 2021-10-29 梅尔兹制药公司 肉毒神经毒素用于治疗震颤的新用途
US11054185B1 (en) * 2020-02-24 2021-07-06 Lyophilization Technology, Inc. Apparatus for lyophilization of products contained in product delivery units
EP3875131A1 (en) * 2020-03-06 2021-09-08 Schott AG Pharmaceutical packaging receptacle with a lubricant layer for removal of a charge
CN115397399A (zh) * 2020-04-08 2022-11-25 玫帝托克斯股份有限公司 一种易于控制排出速度且稳定的肉毒杆菌毒素预填充式注射器剂型
KR102404217B1 (ko) * 2020-04-08 2022-06-02 (주)메디톡스 토출 속도 조절이 용이하고 안정한 보툴리눔 독소 사전충전된 주사기 제형
WO2021042090A2 (en) * 2020-11-27 2021-03-04 Schott Ag System for long time storage of pharmaceutical compositions at low temperatures
US20230204611A1 (en) * 2021-12-28 2023-06-29 Dionex Corporation Identification of sample cells in a chromatography autosampler

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5607400A (en) 1995-05-19 1997-03-04 Becton, Dickinson And Company Pre-fillable syringe and stopper assembly therefor
TW574036B (en) 1998-09-11 2004-02-01 Elan Pharm Inc Stable liquid compositions of botulinum toxin
US20120238504A1 (en) * 1998-09-11 2012-09-20 Solstice Neurosciences, Llc Stable Formulations of Botulinum Toxin in Hydrogels
US20060269575A1 (en) * 2000-02-08 2006-11-30 Allergan, Inc. Botulinum toxin pharmaceutical compositions formulated with recombinant albumin
CA2494241C (en) 2000-02-08 2011-06-14 Allergan, Inc. Botulinum toxin pharmaceutical compositions
US8574146B2 (en) * 2000-04-14 2013-11-05 Attenuex Technologies, Inc. Implant with high vapor pressure medium
DE10333317A1 (de) 2003-07-22 2005-02-17 Biotecon Therapeutics Gmbh Formulierung für Proteinarzneimittel ohne Zusatz von humanem Serumalbumin (HSA)
GB2416122A (en) 2004-07-12 2006-01-18 Ipsen Ltd Botulinum neurotoxin composition
US20080045889A1 (en) 2004-07-21 2008-02-21 Gerondale Scott J Botoxo Needle Injector
US9314416B2 (en) * 2005-03-03 2016-04-19 Revance Therapeutics, Inc. Compositions and methods for topical application and transdermal delivery of botulinum toxins
JP5086235B2 (ja) * 2005-03-09 2012-11-28 クティセンセ アクティーゼルスカブ マイクロ電子システムを内部に埋め込んだ三次元接着デバイス
JP2006314554A (ja) 2005-05-12 2006-11-24 Mitsubishi Pharma Corp ヘパリン溶液プレフィルドシリンジ包装体
ES2401484T3 (es) 2006-06-15 2013-04-22 Novartis Ag Régimen de vacunación contra la gripe multidosis ahorrador de adyuvantes
GB0700523D0 (en) * 2007-01-11 2007-02-21 Insense Ltd The Stabilisation Of Proteins
ES2441961T3 (es) * 2007-02-15 2014-02-07 Allergan, Inc. Composiciones de toxina botulínica y métodos
EP1997509A1 (en) * 2007-06-01 2008-12-03 Merz Pharma GmbH & Co.KGaA Process for providing a temperature-stable muscle relaxant on the basis of the neurotoxic component of botulinum toxin
CN101720331A (zh) 2007-06-01 2010-06-02 德国麦氏大药厂 基于肉毒毒素的神经毒成分供应温度-稳定性肌肉松弛剂的方法
EP2048156A1 (en) * 2007-10-12 2009-04-15 Merz Pharma GmbH & Co.KGaA Process for providing a temperature-stable muscle relaxant on the basis of the neurotoxic component of botulinum toxin
WO2009003010A2 (en) 2007-06-25 2008-12-31 Becton, Dickinson And Company Methods for evaluating the aggregation of a protein in a suspension including organopolysiloxane and medical articles coated with organopolysiloxane containing a protein solution
KR101087017B1 (ko) 2007-07-10 2011-12-09 (주)메디톡스 보툴리눔 독소의 안정성이 개선된 약제학적 액상 조성물
US9107815B2 (en) * 2008-02-22 2015-08-18 Allergan, Inc. Sustained release poloxamer containing pharmaceutical compositions
US8809392B2 (en) * 2008-03-28 2014-08-19 Ecolab Usa Inc. Sulfoperoxycarboxylic acids, their preparation and methods of use as bleaching and antimicrobial agents
US8871807B2 (en) * 2008-03-28 2014-10-28 Ecolab Usa Inc. Detergents capable of cleaning, bleaching, sanitizing and/or disinfecting textiles including sulfoperoxycarboxylic acids
BRPI0913189A2 (pt) * 2008-05-30 2016-01-12 Allergan Inc dispositivo de injeção para cargas de aumento de tecido mole, agentes bioativos e outros materiais biocompatíveis em forma líquida ou gel
EP2364168A1 (en) 2008-12-04 2011-09-14 Botulinum Toxin Research Associates, Inc. Extended length botulinum toxin formulation for human or mammalian use
US8535062B2 (en) * 2008-12-23 2013-09-17 Simskin, Llc Cutaneous surgical training model of the head, neck and shoulders
KR20210141783A (ko) * 2009-06-25 2021-11-23 레반스 테라퓨틱스, 아이엔씨. 알부민­불포함 보툴리눔 독소 제제
US10471212B2 (en) * 2009-10-29 2019-11-12 W. L. Gore & Associates, Inc. Silicone free drug delivery devices
WO2011080543A1 (en) * 2009-12-31 2011-07-07 Becton Dickinson France Medical components having coated surfaces exhibiting low friction and/or low gas/liquid permeability
US20130078295A1 (en) * 2010-06-09 2013-03-28 Lipotec S.A. Skin antiaging treatment
EP2399601A1 (en) 2010-06-24 2011-12-28 Merz Pharma GmbH & Co. KGaA Botulinum toxin therapy
JP5719443B2 (ja) * 2010-09-26 2015-05-20 ダ・ユー・エンタープライジズ、エルエルシー 組換え巨大分子製造方法
FR2966044B1 (fr) 2010-10-18 2012-11-02 Sanofi Pasteur Procede de conditionnement d'un vaccin contenant un adjuvant d'aluminium
CN103930595A (zh) * 2011-11-11 2014-07-16 Sio2医药产品公司 用于药物包装的钝化、pH保护性或润滑性涂层、涂布方法以及设备
US10780228B2 (en) * 2012-05-07 2020-09-22 Medline Industries, Inc. Prefilled container systems
US20150297800A1 (en) * 2012-07-03 2015-10-22 Sio2 Medical Products, Inc. SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS
EP2870273B1 (en) 2012-07-03 2021-11-03 SiO2 Medical Products, Inc. Coating process
US9133412B2 (en) 2012-07-09 2015-09-15 Tribofilm Research, Inc. Activated gaseous species for improved lubrication
WO2014026161A1 (en) * 2012-08-10 2014-02-13 Aquavit Pharmaceuticals, Inc. Vitamin supplement compositions for injection
US10980865B2 (en) * 2012-08-10 2021-04-20 Aquavit Pharmaceuticals, Inc. Direct application system and method for the delivery of bioactive compositions and formulations
WO2014052792A1 (en) 2012-09-28 2014-04-03 Sio2 Medical Products, Inc. Halogenated or parylene polymer coating
EP2961858B1 (en) * 2013-03-01 2022-09-07 Si02 Medical Products, Inc. Coated syringe.
US9937099B2 (en) * 2013-03-11 2018-04-10 Sio2 Medical Products, Inc. Trilayer coated pharmaceutical packaging with low oxygen transmission rate
WO2014164928A1 (en) * 2013-03-11 2014-10-09 Sio2 Medical Products, Inc. Coated packaging
US20160017490A1 (en) * 2013-03-15 2016-01-21 Sio2 Medical Products, Inc. Coating method
DE102014101305A1 (de) * 2014-02-03 2015-08-06 Heraeus Medical Gmbh Vorrichtung zum Lagern und Mischen von Knochenzement
WO2015148688A1 (en) * 2014-03-26 2015-10-01 Nanomed Skincare, Inc. Plunger-like mass transportation device for dermal and transdermal delivery of a liquid or solid composition
EP3188706B1 (en) * 2014-09-02 2019-10-09 American Silver, LLC Botulinum toxin and colloidal silver particles
US20170238580A1 (en) * 2014-11-11 2017-08-24 Pressed Juicery, LLC System and process for destroying c. botulinum spores in pressed beverage using thermal pascalization
KR102557798B1 (ko) * 2014-12-23 2023-07-19 메르츠 파마 게엠베하 운트 코. 카가아 보툴리눔 독소 사전충전된 용기
TWI728964B (zh) * 2015-02-03 2021-06-01 德商梅茲製藥有限兩合公司 預填充式塑膠注射器及其套組與使用
JP2018515271A (ja) * 2015-05-15 2018-06-14 カリリオン・クリニックCarilion Clinic 過活動膀胱を処置するための注射器及びこれら注射器を使用する方法
US9827282B2 (en) * 2015-07-24 2017-11-28 Bao Tran Medication dispensing system
TWI737742B (zh) * 2016-06-22 2021-09-01 德商梅茲製藥有限兩合公司 肉毒桿菌毒素的預填充式注射器系統、具有其之套組以及其之使用

Also Published As

Publication number Publication date
CN107206175B (zh) 2021-06-01
US20190336691A1 (en) 2019-11-07
WO2016124213A1 (en) 2016-08-11
RU2722290C2 (ru) 2020-05-28
EP3253364A1 (en) 2017-12-13
AR103244A1 (es) 2017-04-26
BR112017016759B1 (pt) 2021-01-12
JP7053751B2 (ja) 2022-04-12
JP6813492B2 (ja) 2021-01-13
JP2018506351A (ja) 2018-03-08
KR102627068B1 (ko) 2024-01-18
CA2974450C (en) 2024-01-09
US20220080127A1 (en) 2022-03-17
RU2017125279A (ru) 2019-03-04
AU2015381351B2 (en) 2020-05-14
KR20170109051A (ko) 2017-09-27
IL253429B (en) 2021-08-31
CN107206175A (zh) 2017-09-26
IL253429A0 (en) 2017-09-28
US11219717B2 (en) 2022-01-11
CA2974450A1 (en) 2016-08-11
JP2021041173A (ja) 2021-03-18
SG11201706247VA (en) 2017-08-30
RU2017125279A3 (es) 2019-08-12
TWI728964B (zh) 2021-06-01
TW201637641A (zh) 2016-11-01
US10406290B2 (en) 2019-09-10
US20180015225A1 (en) 2018-01-18
AU2015381351A1 (en) 2017-08-03
BR112017016759A2 (pt) 2018-04-10

Similar Documents

Publication Publication Date Title
MX2017009380A (es) Recipiente precargado con toxina botulinica.
MX2017007476A (es) Recipiente precargado con toxina botulinica.
IL286472A (en) Injectable botulinum toxin formulations and methods of using them with a long-term medical or cosmetic effect
MX2018007703A (es) Inhibidores de la interaccion de menina-linaje leucemico mixto.
AU201613305S (en) Massage head for drug applicator
MX2018006171A (es) Jeringa de plastico precargada que contiene un antagonista de vegf.
AU367093S (en) Medical injector
AU367108S (en) Medical injector
PH12015500115A1 (en) Glucagon analogues
MX2015009106A (es) Composiciones de solución sólida y su uso en el tratamiento del dolor intenso.
BR112017005209A2 (pt) compostos moduladores de pirrolopiridina substituída por metila e trifluorometila de rorc2 e seu uso
MX2023013089A (es) Aplicador de liquidos para suministrar vacunas.
EP3151923A4 (en) Clear compositions and methods for the delivery of active ingredients for skin care
MX2018000570A (es) Nuevas isoformas de tripsina y su uso.
MX2017012596A (es) Una composicion farmaceutica y el uso de la misma.
HK1232165A1 (zh) 注射器蓋、帶針注射器、及預充式注射器製劑
MX2017001917A (es) Composicion de colutorio.
GEP20196977B (en) Pharmaceutical formulations of vildagliptin
MX2018002859A (es) Extracto de gardenia para colorear la piel.
MX2015016410A (es) Esteres de acidos oligo-hidroxicarboxilicos y uso de los mismos.
MX2015016490A (es) Esteres sulfatados de acidos oligohidroxicarboxilicos, y uso de los mismos.
MX2017009313A (es) Formulaciones intravenosas de baclofeno y metodos de tratamiento.
GEP20207145B (en) Combination of trazodone and gabapentin for the treatmen
EA201700074A1 (ru) Стабильные не содержащие консерванты офтальмологические составы опиоидных антагонистов
BR112017013764A2 (pt) recipiente pré-carregado com toxina botulínica