MX2018002778A - Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso. - Google Patents

Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso.

Info

Publication number
MX2018002778A
MX2018002778A MX2018002778A MX2018002778A MX2018002778A MX 2018002778 A MX2018002778 A MX 2018002778A MX 2018002778 A MX2018002778 A MX 2018002778A MX 2018002778 A MX2018002778 A MX 2018002778A MX 2018002778 A MX2018002778 A MX 2018002778A
Authority
MX
Mexico
Prior art keywords
alkyl
substrate
cyclopropanation
olefins
methyl
Prior art date
Application number
MX2018002778A
Other languages
English (en)
Inventor
Schroeder Fridtjof
Steck Marcel
Original Assignee
Givaudan Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Givaudan Sa filed Critical Givaudan Sa
Publication of MX2018002778A publication Critical patent/MX2018002778A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2/00—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms
    • C07C2/86—Preparation of hydrocarbons from hydrocarbons containing a smaller number of carbon atoms by condensation between a hydrocarbon and a non-hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C241/00—Preparation of compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
    • C07C13/02—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
    • C07C13/04—Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/04—N-nitroso compounds
    • C07C243/06—N-nitroso-amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
    • C07C2523/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
    • C07C2523/44—Palladium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2531/00—Catalysts comprising hydrides, coordination complexes or organic compounds
    • C07C2531/16—Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes
    • C07C2531/20—Carbonyls
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)

Abstract

Un proceso para convertir un doble enlace de carbono-carbono en un sustrato en un anillo de ciclopropano, método que comprende el paso de tratar el sustrato con un compuesto de N-alquil-N-nitroso, un catalizador de metal de transición y una base acuosa, en donde el compuesto de N-alquil-N-nitroso se forma al hacer reaccionar una alquil-amina con un nitrito de metal alcalino en la presencia de un ácido monobásico o dibásico, o una mezcla de los mismos, y en donde el compuesto de N-alquil-N-nitroso no se destila antes de que se mezcle con el sustrato, el catalizador y la base.
MX2018002778A 2015-09-16 2016-09-14 Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso. MX2018002778A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1516396.7A GB201516396D0 (en) 2015-09-16 2015-09-16 Improvements in or relating to organic compounds
PCT/EP2016/071630 WO2017046122A1 (en) 2015-09-16 2016-09-14 Process for the cyclopropanation of olefins using n-methyl-n-nitroso compounds

Publications (1)

Publication Number Publication Date
MX2018002778A true MX2018002778A (es) 2018-04-13

Family

ID=54363254

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2018002778A MX2018002778A (es) 2015-09-16 2016-09-14 Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso.
MX2022014035A MX2022014035A (es) 2015-09-16 2018-03-05 Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022014035A MX2022014035A (es) 2015-09-16 2018-03-05 Proceso para la ciclopropanacion de olefinas utilizando compuestos de n-metil-n-nitroso.

Country Status (11)

Country Link
US (2) US10611704B2 (es)
EP (2) EP3350144B1 (es)
JP (2) JP6884767B2 (es)
CN (2) CN108025997B (es)
BR (1) BR112018004042B1 (es)
ES (1) ES2887223T3 (es)
GB (1) GB201516396D0 (es)
IL (2) IL257799B (es)
MX (2) MX2018002778A (es)
SG (1) SG10202003047PA (es)
WO (1) WO2017046122A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201516396D0 (en) * 2015-09-16 2015-10-28 Givaudan Sa Improvements in or relating to organic compounds
CN108484347B (zh) * 2018-04-28 2021-02-05 江苏八巨药业有限公司 一种末端异戊二烯类化合物环丙烷化的制备方法
GB201810514D0 (en) 2018-06-27 2018-08-15 Givaudan Sa Improvements in or relating to organic compounds
WO2021000248A1 (zh) 2019-07-02 2021-01-07 凯莱英医药集团（天津）股份有限公司 环丙烷类化合物连续合成的方法及装置
CN113275032A (zh) * 2020-02-20 2021-08-20 太原理工大学 用于甲苯甲醇侧链烷基化的分子筛催化剂及其制备方法和应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE855551C (de) 1942-05-13 1952-11-13 Knoll Ag Verfahren zur Herstellung von Mono- bzw. symmetrischem Dimethylharnstoff
US2960536A (en) * 1957-04-11 1960-11-15 Fmc Corp Process for the production of nitrosamines
JPS4933933B1 (es) * 1970-02-16 1974-09-11
JPS54160325A (en) 1978-06-05 1979-12-19 Mitsubishi Petrochem Co Ltd Nitrosation
US4650881A (en) 1985-04-01 1987-03-17 Iowa State University Research Foundation, Inc. Synthesis of isocoumarins via thallation-olefination of arenes
US5854405A (en) * 1997-11-13 1998-12-29 Aerojet-General Corporation Continuous process for diazomethane from an n-methyl-n-nitrosoamine and from methylurea through n-methyl-n-nitrosourea
GB2357501B (en) 1999-12-23 2001-11-28 Phoenix Chemicals Ltd Generation of diazomethane
EP1269982A1 (en) 2001-06-30 2003-01-02 Givaudan SA Fragrance and flavour compositions
WO2010131146A1 (en) 2009-05-12 2010-11-18 Pfizer Limited Cyclobutenedione derivatives
EP3404108A1 (de) 2009-06-05 2018-11-21 Basf Se Biokatalytische herstellung von ambroxan
JP2011105691A (ja) * 2009-11-20 2011-06-02 M Carreira Erick トリフルオロメチルシクロプロパン化合物の製造方法
CN102127070A (zh) * 2010-01-15 2011-07-20 山东轩竹医药科技有限公司 吡啶并环衍生物
US9073924B2 (en) 2011-09-13 2015-07-07 Glaxosmithkline Llc Azaindazoles
GB201201066D0 (en) 2012-01-23 2012-03-07 Bakhu Ltd A method for the preparation of diazoalkanes
US20130273619A1 (en) 2012-04-16 2013-10-17 Basf Se Process for the Preparation of (3E, 7E)-Homofarnesol
CN102976945A (zh) * 2012-12-29 2013-03-20 贵阳柏丝特化工有限公司 一种利用微反应器合成菊酸乙酯化合物的方法
GB201318894D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements in or relating to organic compounds
GB201318886D0 (en) 2013-10-25 2013-12-11 Givaudan Sa Improvements i or relating to organic compounds
GB201319677D0 (en) * 2013-11-07 2013-12-25 Eth Z Rich Cyclopropanation
GB201516396D0 (en) * 2015-09-16 2015-10-28 Givaudan Sa Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
JP2018527373A (ja) 2018-09-20
GB201516396D0 (en) 2015-10-28
ES2887223T3 (es) 2021-12-22
CN108025997B (zh) 2021-01-15
EP3350144A1 (en) 2018-07-25
EP3350144B1 (en) 2021-06-23
US11034628B2 (en) 2021-06-15
SG10202003047PA (en) 2020-05-28
US10611704B2 (en) 2020-04-07
WO2017046122A1 (en) 2017-03-23
JP7330226B2 (ja) 2023-08-21
JP6884767B2 (ja) 2021-06-09
CN108025997A (zh) 2018-05-11
BR112018004042B1 (pt) 2022-03-22
JP2021113234A (ja) 2021-08-05
IL257799B (en) 2020-10-29
IL278017B (en) 2021-10-31
EP3882230A1 (en) 2021-09-22
CN112778071A (zh) 2021-05-11
BR112018004042A2 (es) 2018-10-02
IL257799A (en) 2018-04-30
US20200172453A1 (en) 2020-06-04
IL278017A (en) 2020-11-30
MX2022014035A (es) 2022-11-30
US20190055172A1 (en) 2019-02-21

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