MX2017007930A - Sistemas de modificación de genoma fúngico y métodos de uso. - Google Patents

Sistemas de modificación de genoma fúngico y métodos de uso.

Info

Publication number
MX2017007930A
MX2017007930A MX2017007930A MX2017007930A MX2017007930A MX 2017007930 A MX2017007930 A MX 2017007930A MX 2017007930 A MX2017007930 A MX 2017007930A MX 2017007930 A MX2017007930 A MX 2017007930A MX 2017007930 A MX2017007930 A MX 2017007930A
Authority
MX
Mexico
Prior art keywords
methods
genome modification
modification systems
genome
fungal genome
Prior art date
Application number
MX2017007930A
Other languages
English (en)
Inventor
Ward Michael
Ge Jing
S Bower Benjamin
Chan Jimmy
Gu Xiaogang
Mampusti Madrid Susan
Song Danfeng
Song Mingmin
Sungjin KIM Steven
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of MX2017007930A publication Critical patent/MX2017007930A/es

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPRs]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Se proporcionan composiciones y métodos para la modificación genómica en un sitio diana en el genoma de una célula fúngica filamentosa. Lo métodos y composiciones tratan de un sistema de polinucleótido guía/ endonucleasa Cas para promover la modificación de la secuencia de ADN en un sitio diana en un genoma de célula hospedadora fúngica.
MX2017007930A 2014-12-16 2015-12-16 Sistemas de modificación de genoma fúngico y métodos de uso. MX2017007930A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN2014093918 2014-12-16
CN2014093914 2014-12-16
CN2014093916 2014-12-16
PCT/US2015/066192 WO2016100568A1 (en) 2014-12-16 2015-12-16 Fungal genome modification systems and methods of use

Publications (1)

Publication Number Publication Date
MX2017007930A true MX2017007930A (es) 2018-01-11

Family

ID=55083496

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2017007928A MX2017007928A (es) 2014-12-16 2015-12-15 Sistemas de modificación de genoma fúngico y métodos de uso.
MX2017008036A MX2017008036A (es) 2014-12-16 2015-12-16 Sistemas de modificacion del genoma fungico y metodos de uso.
MX2017007930A MX2017007930A (es) 2014-12-16 2015-12-16 Sistemas de modificación de genoma fúngico y métodos de uso.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2017007928A MX2017007928A (es) 2014-12-16 2015-12-15 Sistemas de modificación de genoma fúngico y métodos de uso.
MX2017008036A MX2017008036A (es) 2014-12-16 2015-12-16 Sistemas de modificacion del genoma fungico y metodos de uso.

Country Status (11)

Country Link
US (3) US11427829B2 (es)
EP (3) EP3234150A1 (es)
JP (3) JP6814142B2 (es)
KR (3) KR102350405B1 (es)
CN (3) CN107667171A (es)
AU (3) AU2015362784B2 (es)
BR (3) BR112017012837A2 (es)
CA (3) CA2971187C (es)
DK (1) DK3234152T3 (es)
MX (3) MX2017007928A (es)
WO (3) WO2016100272A1 (es)

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AU2015364632A1 (en) 2017-07-06
WO2016100568A1 (en) 2016-06-23
AU2015364629B2 (en) 2021-05-13
JP2017538425A (ja) 2017-12-28
BR112017012850A2 (pt) 2017-12-26
BR112017012837A2 (pt) 2017-12-26
CN107257859A (zh) 2017-10-17
CA2971187A1 (en) 2016-06-23
AU2015362784A1 (en) 2017-07-06
JP6814141B2 (ja) 2021-01-13
MX2017008036A (es) 2017-09-28
KR20170087521A (ko) 2017-07-28
EP3234152B1 (en) 2021-09-15
CA2971248A1 (en) 2016-06-23
JP2017537647A (ja) 2017-12-21
US11427829B2 (en) 2022-08-30
JP6814142B2 (ja) 2021-01-13
KR20170087522A (ko) 2017-07-28
KR102350405B1 (ko) 2022-01-11
JP6814143B2 (ja) 2021-01-13
DK3234152T3 (da) 2021-12-20
AU2015362784B2 (en) 2021-05-13
MX2017007928A (es) 2018-01-30
WO2016100571A1 (en) 2016-06-23
EP3234150A1 (en) 2017-10-25
CA2971187C (en) 2023-10-24
AU2015364632B2 (en) 2021-05-13
KR102350404B1 (ko) 2022-01-11
KR102350402B1 (ko) 2022-01-11
BR112017012851A2 (pt) 2017-12-26
US11098314B2 (en) 2021-08-24
US20170369891A1 (en) 2017-12-28
CA2971247A1 (en) 2016-06-23
CA2971248C (en) 2023-04-04
EP3234152A1 (en) 2017-10-25
KR20170089931A (ko) 2017-08-04
JP2018504895A (ja) 2018-02-22
AU2015364629A1 (en) 2017-07-06
US20190093114A1 (en) 2019-03-28
CN107667171A (zh) 2018-02-06
WO2016100272A1 (en) 2016-06-23
CN107278231A (zh) 2017-10-20
EP3234151A1 (en) 2017-10-25
US20180002710A1 (en) 2018-01-04
US11401522B2 (en) 2022-08-02

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