MX2017007884A - Derivados de tiadiazol amida como inhibidores de la nadph oxidasa. - Google Patents

Derivados de tiadiazol amida como inhibidores de la nadph oxidasa.

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Publication number
MX2017007884A
MX2017007884A MX2017007884A MX2017007884A MX2017007884A MX 2017007884 A MX2017007884 A MX 2017007884A MX 2017007884 A MX2017007884 A MX 2017007884A MX 2017007884 A MX2017007884 A MX 2017007884A MX 2017007884 A MX2017007884 A MX 2017007884A
Authority
MX
Mexico
Prior art keywords
nadph oxidase
oxidase inhibitors
thiadiazole derivatives
amido thiadiazole
amido
Prior art date
Application number
MX2017007884A
Other languages
English (en)
Spanish (es)
Inventor
Machin Peter
Sharpe Andrew
James Lock Christopher
S CHAMBERS Mark
Hodges Alastair
ALLEN Vivienne
M ELLARD John
Original Assignee
Genkyotex Suisse Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genkyotex Suisse Sa filed Critical Genkyotex Suisse Sa
Publication of MX2017007884A publication Critical patent/MX2017007884A/es

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
MX2017007884A 2014-12-17 2015-12-16 Derivados de tiadiazol amida como inhibidores de la nadph oxidasa. MX2017007884A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14198597.8A EP3034500A1 (en) 2014-12-17 2014-12-17 Amido thiazole derivatives as NADPH oxidase inhibitors
PCT/IB2015/059659 WO2016098005A1 (en) 2014-12-17 2015-12-16 Amido thiadiazole derivatives as nadph oxidase inhibitors

Publications (1)

Publication Number Publication Date
MX2017007884A true MX2017007884A (es) 2017-12-14

Family

ID=52146189

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017007884A MX2017007884A (es) 2014-12-17 2015-12-16 Derivados de tiadiazol amida como inhibidores de la nadph oxidasa.

Country Status (13)

Country Link
US (2) US10130619B2 (OSRAM)
EP (2) EP3034500A1 (OSRAM)
JP (1) JP2017537948A (OSRAM)
KR (1) KR20170094263A (OSRAM)
CN (1) CN107207489A (OSRAM)
AU (1) AU2015365465B2 (OSRAM)
BR (1) BR112017012846A2 (OSRAM)
CA (1) CA2971357A1 (OSRAM)
HK (1) HK1245777A1 (OSRAM)
IL (1) IL252928A0 (OSRAM)
MX (1) MX2017007884A (OSRAM)
RU (1) RU2017121044A (OSRAM)
WO (1) WO2016098005A1 (OSRAM)

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US11970486B2 (en) 2016-10-24 2024-04-30 Janssen Pharmaceutica Nv Compounds and uses thereof
AU2018205275B2 (en) 2017-01-06 2024-05-02 Janssen Pharmaceutica Nv Methods for the treatment of neurological disorders
US11873298B2 (en) 2017-10-24 2024-01-16 Janssen Pharmaceutica Nv Compounds and uses thereof
EP3479843A1 (en) * 2017-11-01 2019-05-08 GenKyoTex Suisse SA Use of nox inhibitors for treatment of cancer
AU2019238326B2 (en) 2018-03-23 2025-03-06 Janssen Pharmaceutica Nv Compounds and uses thereof
KR20220007845A (ko) 2019-01-24 2022-01-19 유마니티 테라퓨틱스, 인크. 화합물 및 이의 용도
US20230078764A1 (en) * 2019-03-22 2023-03-16 Yumanity Therapeutics, Inc. Compounds and uses thereof
US20230078112A1 (en) * 2019-05-31 2023-03-16 Ideaya Biosciences, Inc. Thiadiazolyl derivatives
AU2020289560A1 (en) 2019-06-05 2021-12-23 Emory University Peptidomimetics for the treatment of coronavirus and picornavirus infections
CN110590706B (zh) * 2019-11-06 2021-07-27 四平市精细化学品有限公司 一种n-甲基吡咯烷的制备方法
EA202192047A1 (ru) 2019-11-13 2021-12-08 Юманити Терапьютикс, Инк. Соединения и их применение
TW202237595A (zh) * 2020-12-02 2022-10-01 美商愛德亞生物科學公司 作為DNA聚合酶θ抑制劑之經取代噻二唑基衍生物
CN117083271A (zh) * 2020-12-02 2023-11-17 伊迪亚生物科学有限公司 作为DNA聚合酶θ抑制剂的取代的噻二唑基衍生物
TW202315618A (zh) * 2021-06-11 2023-04-16 美商愛德亞生物科學公司 作為DNA聚合酶θ抑制劑之O-聯結噻二唑基化合物
WO2023060573A1 (en) * 2021-10-15 2023-04-20 Beijing Danatlas Pharmaceutical Co., Ltd. Novel thiadiazolyl derivatives of dna polymerase theta inhibitors
KR102422881B1 (ko) * 2021-11-08 2022-07-20 (주)셀로스바이오텍 신규 옥사다이아졸 유도체 및 이의 용도
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions
TW202448435A (zh) * 2023-02-28 2024-12-16 美商賽堤爾醫療公司 經取代之噻二唑基化合物
CN120917019A (zh) * 2023-04-13 2025-11-07 北京丹擎医药科技有限公司 噻二唑酮衍生物及其组合物和应用

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RU2017121044A (ru) 2018-12-17
KR20170094263A (ko) 2017-08-17
BR112017012846A2 (pt) 2017-12-26
IL252928A0 (en) 2017-08-31
US10130619B2 (en) 2018-11-20
EP3233847A1 (en) 2017-10-25
JP2017537948A (ja) 2017-12-21
CA2971357A1 (en) 2016-06-23
HK1245777A1 (zh) 2018-08-31
WO2016098005A1 (en) 2016-06-23
RU2017121044A3 (OSRAM) 2019-03-22
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US20190046515A1 (en) 2019-02-14
AU2015365465B2 (en) 2019-12-12

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