MX2017004448A - Compuestos anti-factor de necrosis tumoral (tnf). - Google Patents

Compuestos anti-factor de necrosis tumoral (tnf).

Info

Publication number
MX2017004448A
MX2017004448A MX2017004448A MX2017004448A MX2017004448A MX 2017004448 A MX2017004448 A MX 2017004448A MX 2017004448 A MX2017004448 A MX 2017004448A MX 2017004448 A MX2017004448 A MX 2017004448A MX 2017004448 A MX2017004448 A MX 2017004448A
Authority
MX
Mexico
Prior art keywords
tnf compounds
tnfa
antisense oligonucleotides
tnf
compounds
Prior art date
Application number
MX2017004448A
Other languages
English (en)
Inventor
Weston Daniel
Gryaznov Sergei
C Mader Christopher
L Halo Tiffany
Kang Richard
Original Assignee
Exicure Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55653658&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2017004448(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Exicure Inc filed Critical Exicure Inc
Publication of MX2017004448A publication Critical patent/MX2017004448A/es

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
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Abstract

En el presente documento, se proporcionan oligonucleótidos antisentido de TNF-a; se proporcionan métodos de tratamiento de enfermedades o trastornos de TNF-a usando los oligonucleótidos antisentido de TNF-a y productos relacionados.
MX2017004448A 2014-10-06 2015-10-06 Compuestos anti-factor de necrosis tumoral (tnf). MX2017004448A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462060424P 2014-10-06 2014-10-06
PCT/US2015/054288 WO2016057549A1 (en) 2014-10-06 2015-10-06 Anti-tnf compounds

Publications (1)

Publication Number Publication Date
MX2017004448A true MX2017004448A (es) 2017-10-23

Family

ID=55653658

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2017004448A MX2017004448A (es) 2014-10-06 2015-10-06 Compuestos anti-factor de necrosis tumoral (tnf).

Country Status (18)

Country Link
US (3) US10208310B2 (es)
EP (1) EP3204499A4 (es)
JP (1) JP6741673B2 (es)
KR (1) KR20170063949A (es)
CN (1) CN107002081A (es)
AU (1) AU2015328242A1 (es)
BR (1) BR112017007012A2 (es)
CA (1) CA2963931A1 (es)
CL (1) CL2017000806A1 (es)
CO (1) CO2017004314A2 (es)
CR (1) CR20170181A (es)
EA (1) EA201790802A1 (es)
IL (1) IL251508A0 (es)
MX (1) MX2017004448A (es)
PE (1) PE20170694A1 (es)
PH (1) PH12017500601A1 (es)
SG (1) SG11201702656WA (es)
WO (1) WO2016057549A1 (es)

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US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
CN105579582A (zh) 2013-07-25 2016-05-11 埃克西奎雷股份有限公司 用于预防和治疗用途的作为免疫刺激剂的基于球形核酸的构建体
US10568898B2 (en) 2013-08-13 2020-02-25 Northwestern University Lipophilic nanoparticles for drug delivery
CN112107693B (zh) 2013-12-03 2023-05-26 西北大学 脂质体颗粒、制备所述脂质体颗粒的方法以及其用途
US10413565B2 (en) 2014-04-30 2019-09-17 Northwestern University Nanostructures for modulating intercellular communication and uses thereof
EP3164113B1 (en) 2014-06-04 2019-03-27 Exicure, Inc. Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
EP3204499A4 (en) 2014-10-06 2018-04-25 Exicure, Inc. Anti-tnf compounds
JP2017537619A (ja) 2014-11-21 2017-12-21 ノースウェスタン ユニバーシティ 球状核酸ナノ粒子複合体の配列特異的細胞内取込
US10704043B2 (en) * 2015-01-14 2020-07-07 Exicure, Inc. Nucleic acid nanostructures with core motifs
WO2016149323A1 (en) * 2015-03-16 2016-09-22 Exicure, Inc. Immunomodulatory spherical nucleic acids
US10078092B2 (en) 2015-03-18 2018-09-18 Northwestern University Assays for measuring binding kinetics and binding capacity of acceptors for lipophilic or amphiphilic molecules
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