MX2016015934A - Marcadores metilados para cancer colorrectal. - Google Patents

Marcadores metilados para cancer colorrectal.

Info

Publication number
MX2016015934A
MX2016015934A MX2016015934A MX2016015934A MX2016015934A MX 2016015934 A MX2016015934 A MX 2016015934A MX 2016015934 A MX2016015934 A MX 2016015934A MX 2016015934 A MX2016015934 A MX 2016015934A MX 2016015934 A MX2016015934 A MX 2016015934A
Authority
MX
Mexico
Prior art keywords
colorectal cancer
methylated markers
colorectal neoplasms
methylated
markers
Prior art date
Application number
MX2016015934A
Other languages
English (en)
Other versions
MX370850B (es
Inventor
Pedersen Susanne
Lapointe Lawrence
Baker Rohan
C Donahue Amber
Lin Peng Yen-
Waldman Frederic
Original Assignee
Quest Diagnostics Invest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Diagnostics Invest Inc filed Critical Quest Diagnostics Invest Inc
Publication of MX2016015934A publication Critical patent/MX2016015934A/es
Publication of MX370850B publication Critical patent/MX370850B/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención describe una combinación de secuencias genomicas cuyos patrones de metilación tiene la utilidad de detección mejorada y diferenciación de neoplasmas colorrectales. Posteriormente, se describen métodos, ácidos nucleicos y estuches de ensayo para detectar o diferenciar los neoplasmas colorrectales.
MX2016015934A 2014-06-04 2015-06-03 Marcadores metilados para cancer colorrectal. MX370850B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462007687P 2014-06-04 2014-06-04
PCT/US2015/033968 WO2015187823A2 (en) 2014-06-04 2015-06-03 Methylated markers for colorectal cancer

Publications (2)

Publication Number Publication Date
MX2016015934A true MX2016015934A (es) 2017-09-01
MX370850B MX370850B (es) 2020-01-08

Family

ID=54767574

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016015934A MX370850B (es) 2014-06-04 2015-06-03 Marcadores metilados para cancer colorrectal.

Country Status (14)

Country Link
US (2) US11486007B2 (es)
EP (1) EP3152333B1 (es)
JP (2) JP6722659B2 (es)
KR (2) KR102587812B1 (es)
CN (1) CN106574303A (es)
AU (2) AU2015271697B2 (es)
BR (1) BR112016028521B1 (es)
CA (1) CA2951141C (es)
IL (2) IL280521B (es)
MX (1) MX370850B (es)
NZ (1) NZ727493A (es)
PH (1) PH12016502417A1 (es)
WO (1) WO2015187823A2 (es)
ZA (1) ZA201700031B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX368034B (es) * 2012-05-11 2019-09-17 Clinical Genomics Pty Ltd Panel de marcadores genéticos para el diagnóstico de cáncer colorrectal.
SI3408407T1 (sl) * 2016-01-29 2021-04-30 Epigenomics Ag Postopki za odkrivanje CPG metilacije iz tumorja pridobljene DNA v vzorcih krvi
CN110770354B (zh) 2017-04-19 2024-03-19 鹍远基因公司 用于文库构建和序列分析的组合物和方法
CN107164535A (zh) * 2017-07-07 2017-09-15 沈阳宁沪科技有限公司 一种无创高通量甲基化结肠癌诊断、研究和治疗方法
WO2019144277A1 (zh) * 2018-01-23 2019-08-01 北京艾克伦医疗科技有限公司 鉴定结直肠癌状态的方法和试剂盒
EP3792363B1 (en) * 2018-01-23 2024-06-26 Excellen Medical Technology Co., Ltd. Method and kit for identifying lung cancer status
EP3766076A4 (en) 2018-03-15 2021-12-29 Grail, Inc. Tissue-specific methylation marker
CN110512001A (zh) * 2018-05-22 2019-11-29 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化试剂、试剂盒及其应用
CN110283913A (zh) * 2019-07-21 2019-09-27 广州奥百阕谱生物科技有限公司 Rassf1a基因甲基化状态检测试剂盒及其应用
KR102261606B1 (ko) * 2019-11-07 2021-06-07 (주)지노믹트리 대장암 검출 방법
KR102478720B1 (ko) * 2019-11-08 2022-12-19 주식회사 아이엠비디엑스 혈액 기반 대장암 진단용 dna 메틸화 바이오마커 패널
US20230193395A1 (en) * 2020-03-20 2023-06-22 Singlera Health Technologies (Shanghai) Ltd. Methods and kits for screening colorectal neoplasm

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7718364B2 (en) * 2003-03-25 2010-05-18 John Wayne Cancer Institute DNA markers for management of cancer
CN101160411B (zh) * 2005-04-15 2014-05-14 Epi基因组股份公司 分析细胞增殖性病症的方法和核酸
AU2007237444B2 (en) * 2006-04-17 2013-05-23 Epigenomics Ag Methods and nucleic acids for the detection of colorectal cell proliferative disorders
US20090317810A1 (en) * 2006-04-17 2009-12-24 Epigenomics Ag Methods and nucleic acids for the detection of colorectal cell proliferative disorders
EP2634265B1 (en) * 2006-07-21 2016-09-14 Epigenomics AG Methods related to the gene GLI3 for detection of colorectal cancer
EP2255017A1 (en) * 2008-03-18 2010-12-01 Epigenomics AG A method for optimizing and validating an assay for determining the presence or absence of a medical condition
ES2760919T3 (es) * 2010-09-13 2020-05-18 Clinical Genomics Pty Ltd Diagnóstico de cáncer mediante marcador de metilación
WO2013007702A1 (en) * 2011-07-08 2013-01-17 Epigenomics Ag Methods and nucleic acids for determining the prognosis of a cancer subject
MX368034B (es) * 2012-05-11 2019-09-17 Clinical Genomics Pty Ltd Panel de marcadores genéticos para el diagnóstico de cáncer colorrectal.
EP4116437A1 (en) * 2012-05-18 2023-01-11 Clinical Genomics Pty. Ltd. A method of screening for colorectal cancer
CN103789428B (zh) * 2014-01-22 2015-04-15 北京神源德生物科技有限公司 引物对及其应用及检测sept9dna甲基化状态的试剂盒

Also Published As

Publication number Publication date
PH12016502417A1 (en) 2017-02-27
JP2017516504A (ja) 2017-06-22
KR102587812B1 (ko) 2023-10-10
BR112016028521A2 (pt) 2018-01-09
AU2015271697B2 (en) 2021-11-04
US11486007B2 (en) 2022-11-01
BR112016028521B1 (pt) 2023-03-14
US20170191135A1 (en) 2017-07-06
AU2022200667A1 (en) 2022-02-24
WO2015187823A2 (en) 2015-12-10
IL249365A0 (en) 2017-02-28
IL249365B (en) 2021-02-28
CA2951141C (en) 2021-11-30
IL280521A (en) 2021-03-01
ZA201700031B (en) 2020-05-27
CA2951141A1 (en) 2015-12-10
AU2015271697A1 (en) 2017-01-12
WO2015187823A3 (en) 2016-03-17
EP3152333A4 (en) 2018-01-03
MX370850B (es) 2020-01-08
EP3152333A2 (en) 2017-04-12
JP6722659B2 (ja) 2020-07-15
CN106574303A (zh) 2017-04-19
IL280521B (en) 2022-07-01
EP3152333B1 (en) 2019-09-11
KR102461235B1 (ko) 2022-10-28
US20230212685A1 (en) 2023-07-06
KR20220150423A (ko) 2022-11-10
KR20170052532A (ko) 2017-05-12
JP7000504B2 (ja) 2022-02-04
NZ727493A (en) 2023-07-28
JP2020191876A (ja) 2020-12-03

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