MX2016009937A - Variantes de quimosina con propiedades mejoradas de coagulacion de la leche. - Google Patents

Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Info

Publication number
MX2016009937A
MX2016009937A MX2016009937A MX2016009937A MX2016009937A MX 2016009937 A MX2016009937 A MX 2016009937A MX 2016009937 A MX2016009937 A MX 2016009937A MX 2016009937 A MX2016009937 A MX 2016009937A MX 2016009937 A MX2016009937 A MX 2016009937A
Authority
MX
Mexico
Prior art keywords
chymosin
variants
improved milk
clotting properties
clotting
Prior art date
Application number
MX2016009937A
Other languages
English (en)
Spanish (es)
Inventor
Lund Martin
Jacobsen Jonas
Jeppesen Iben
Maarten Van Den Brink Johannes
Langholm Jensen Jesper
Jaeckel Christian
Original Assignee
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen As filed Critical Chr Hansen As
Publication of MX2016009937A publication Critical patent/MX2016009937A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6478Aspartic endopeptidases (3.4.23)
    • C12N9/6483Chymosin (3.4.23.4), i.e. rennin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C19/00Cheese; Cheese preparations; Making thereof
    • A23C19/02Making cheese curd
    • A23C19/04Making cheese curd characterised by the use of specific enzymes of vegetable or animal origin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C19/00Cheese; Cheese preparations; Making thereof
    • A23C19/02Making cheese curd
    • A23C19/04Making cheese curd characterised by the use of specific enzymes of vegetable or animal origin
    • A23C19/041Proteolytic or milk clotting enzymes from plants or vegetables, e.g. papain, ficin, bromelain
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23CDAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; PREPARATION THEREOF
    • A23C9/00Milk preparations; Milk powder or milk powder preparations
    • A23C9/12Fermented milk preparations; Treatment using microorganisms or enzymes
    • A23C9/1203Addition of, or treatment with, enzymes or microorganisms other than lactobacteriaceae
    • A23C9/1209Proteolytic or milk coagulating enzymes, e.g. trypsine
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23Aspartic endopeptidases (3.4.23)
    • C12Y304/23004Chymosin (3.4.23.4), i.e. rennin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Husbandry (AREA)
  • Botany (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Fodder In General (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
MX2016009937A 2014-02-26 2015-02-26 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche. MX2016009937A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14156707 2014-02-26
EP14176664 2014-07-11
PCT/EP2015/054020 WO2015128417A1 (en) 2014-02-26 2015-02-26 Variants of chymosin with improved milk-clotting properties

Publications (1)

Publication Number Publication Date
MX2016009937A true MX2016009937A (es) 2016-10-31

Family

ID=52596486

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2016009937A MX2016009937A (es) 2014-02-26 2015-02-26 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.
MX2022006692A MX2022006692A (es) 2014-02-26 2016-07-29 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2022006692A MX2022006692A (es) 2014-02-26 2016-07-29 Variantes de quimosina con propiedades mejoradas de coagulacion de la leche.

Country Status (14)

Country Link
US (4) US10982204B2 (https=)
EP (2) EP3110948B1 (https=)
JP (3) JP7098270B2 (https=)
KR (2) KR102494645B1 (https=)
CN (2) CN106062187B (https=)
AU (2) AU2015222149B2 (https=)
BR (1) BR112016017502B1 (https=)
CA (1) CA2938015A1 (https=)
DK (1) DK3110948T3 (https=)
MX (2) MX2016009937A (https=)
NZ (1) NZ722003A (https=)
RU (2) RU2717770C2 (https=)
UA (1) UA121380C2 (https=)
WO (1) WO2015128417A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ702030A (en) 2012-05-25 2016-11-25 Chr Hansen As Variants of chymosin with improved milk-clotting properties
RU2717770C2 (ru) 2014-02-26 2020-03-25 Кхр. Хансен А/С Варианты химозина с улучшенными молокосвертывающими свойствами
RU2740317C2 (ru) * 2015-06-22 2021-01-13 Кхр. Хансен А/С Варианты химозина с улучшенными свойствами
EP3344049A1 (en) * 2015-08-31 2018-07-11 Chr. Hansen A/S Variants of chymosin with improved properties
ES3023033T3 (en) * 2015-09-18 2025-05-29 Dsm Ip Assets Bv Yogurt with reduced ripening
EP3457859A1 (en) * 2016-05-19 2019-03-27 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
US10961524B2 (en) 2016-05-19 2021-03-30 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
CN106754840B (zh) * 2016-12-22 2019-06-21 江南大学 一种酶活及热稳定性改善的凝乳酶突变体
US20200345022A1 (en) 2018-01-15 2020-11-05 Chr. Hansen A/S Fermented milk product and preparation thereof using phospholipase
CN113801867B (zh) * 2021-11-18 2022-03-18 中国农业科学院生物技术研究所 骆驼凝乳酶原突变蛋白及其编码基因和应用
US20260000087A1 (en) 2022-04-06 2026-01-01 Chr. Hansen A/S Aspartic Protease, Methods and Uses Thereof
WO2024189187A1 (en) 2023-03-15 2024-09-19 Dsm Ip Assets B.V. Novel process for producing a fermented milk product and new fermented milk product so produced

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123928A3 (en) 1983-03-31 1986-02-05 Codon Genetic Engineering Laboratories Recombinant dna coding for a polypeptide displaying milk clotting activity
US5217891A (en) * 1987-07-28 1993-06-08 Chiron Corporation DNA constructs containing a kluyveromyces α factor leader sequence for directing secretion of heterologous polypeptides
US7390936B1 (en) * 1999-08-23 2008-06-24 Sembiosys Genetics Inc. Commercial production of chymosin in plants
RU2192137C2 (ru) 2000-08-07 2002-11-10 Открытое акционерное общество "Уфамолагропром" Способ производства сыра
DK1334182T4 (da) * 2000-11-06 2021-04-26 Eidgenoessische Technische Hochschule Eth Fremgangsmåde til fremstilling af ikke-bovint chymosin og anvendelse heraf
AU2003282724B2 (en) 2002-10-02 2010-03-04 Catalyst Biosciences, Inc. Methods of generating and screening for proteases with altered specificity
WO2004072225A2 (en) 2003-02-12 2004-08-26 Ramot At Tel Aviv University Ltd. Transgenic fungi expressing bcl-2 and methods of using bcl-2 or portions thereof for improving biomass production, survival, longevity, stress resistance and pathogenicity of fungi
BRPI0412007A (pt) 2003-06-27 2006-08-15 Bioren Inc mutagênese look-through
EP1745068A4 (en) * 2004-03-30 2009-11-04 Sudershan Biotech Ltd RECOMBINANT CALM CHYMOSIN AND PROCESS FOR PRODUCING THE SAME
EP3763220A1 (en) 2007-02-13 2021-01-13 Chr. Hansen A/S Coagulation of milk
JP2010046034A (ja) 2008-08-22 2010-03-04 Toyota Central R&D Labs Inc 変異体のスクリーニング方法
EP2411512B1 (en) * 2009-03-24 2013-11-20 Meito Sangyo Co., Ltd. Improved type milk-clotting protease derived from a microorganism
DK2602317T3 (da) * 2009-11-20 2017-11-13 Danisco Us Inc Beta-glucosidasevarianter med forbedrede egenskaber
KR20130102534A (ko) * 2010-07-12 2013-09-17 에이티와이알 파마, 인코포레이티드 히스티딜­trna 합성효소의 단백질 단편에 관련된 치료적, 진단적, 및 항체 조성물의 혁신적 발견
EA035275B1 (ru) * 2012-05-03 2020-05-22 ДСМ АйПи АССЕТС Б.В. Варианты химозина с повышенной специфичностью и их применение в получении сыра
NZ702030A (en) 2012-05-25 2016-11-25 Chr Hansen As Variants of chymosin with improved milk-clotting properties
CN103484488B (zh) * 2013-09-16 2015-07-15 中国农业科学院生物技术研究所 优化的牛凝乳酶原基因及其分泌表达方法和应用
RU2717770C2 (ru) 2014-02-26 2020-03-25 Кхр. Хансен А/С Варианты химозина с улучшенными молокосвертывающими свойствами
US20180110234A1 (en) 2015-02-10 2018-04-26 Chr. Hansen A/S Blends of chymosins with improved milk-clotting properties
RU2740317C2 (ru) 2015-06-22 2021-01-13 Кхр. Хансен А/С Варианты химозина с улучшенными свойствами
EP3344049A1 (en) 2015-08-31 2018-07-11 Chr. Hansen A/S Variants of chymosin with improved properties
EP3457859A1 (en) 2016-05-19 2019-03-27 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties
US10961524B2 (en) 2016-05-19 2021-03-30 Chr. Hansen A/S Variants of chymosin with improved milk-clotting properties

Also Published As

Publication number Publication date
AU2015222149B2 (en) 2021-09-23
US20220154162A1 (en) 2022-05-19
KR20160125459A (ko) 2016-10-31
DK3110948T3 (da) 2025-05-12
KR102344861B1 (ko) 2021-12-29
JP2020141667A (ja) 2020-09-10
AU2021286442A1 (en) 2022-01-20
CA2938015A1 (en) 2015-09-03
BR112016017502A2 (https=) 2017-08-08
BR112016017502B1 (pt) 2023-10-24
US20170067041A1 (en) 2017-03-09
AU2015222149A1 (en) 2016-07-28
WO2015128417A1 (en) 2015-09-03
NZ722003A (en) 2023-06-30
JP7098270B2 (ja) 2022-07-11
JP2017512059A (ja) 2017-05-18
UA121380C2 (uk) 2020-05-25
CN106062187A (zh) 2016-10-26
US11827913B2 (en) 2023-11-28
JP7144470B2 (ja) 2022-09-29
EP4627930A2 (en) 2025-10-08
KR20220002714A (ko) 2022-01-06
JP2022122926A (ja) 2022-08-23
EP3110948B1 (en) 2025-04-09
RU2016132974A (ru) 2018-03-27
CN106062187B (zh) 2020-09-15
CN111944791A (zh) 2020-11-17
KR102494645B1 (ko) 2023-02-06
RU2717770C2 (ru) 2020-03-25
RU2739004C1 (ru) 2020-12-21
US20210230571A1 (en) 2021-07-29
US11629343B2 (en) 2023-04-18
US20240084281A1 (en) 2024-03-14
EP4627930A3 (en) 2026-03-04
AU2021286442B2 (en) 2024-12-12
RU2016132974A3 (https=) 2018-09-18
US10982204B2 (en) 2021-04-20
MX2022006692A (es) 2022-07-11
EP3110948A1 (en) 2017-01-04

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