MX2015008177A - Evaluacion de la actividad de la via de señalizacion celular utilizando combinacion(es) lineal(es) de expresiones de genes objetivo. - Google Patents

Evaluacion de la actividad de la via de señalizacion celular utilizando combinacion(es) lineal(es) de expresiones de genes objetivo.

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Publication number
MX2015008177A
MX2015008177A MX2015008177A MX2015008177A MX2015008177A MX 2015008177 A MX2015008177 A MX 2015008177A MX 2015008177 A MX2015008177 A MX 2015008177A MX 2015008177 A MX2015008177 A MX 2015008177A MX 2015008177 A MX2015008177 A MX 2015008177A
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Mexico
Prior art keywords
signaling pathway
cellular signaling
target gene
assessment
linear combination
Prior art date
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MX2015008177A
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English (en)
Inventor
Hendrik Jan Van Ooijen
Wilhelmus Franciscus Johannes Verhaegh
Paul Arnold Van De Wiel
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Koninkl Philips Nv
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Publication date
Application filed by Koninkl Philips Nv filed Critical Koninkl Philips Nv
Publication of MX2015008177A publication Critical patent/MX2015008177A/es

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06N—COMPUTING ARRANGEMENTS BASED ON SPECIFIC COMPUTATIONAL MODELS
    • G06N5/00—Computing arrangements using knowledge-based models
    • G06N5/04—Inference or reasoning models
    • G06N5/048—Fuzzy inferencing
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding

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  • General Physics & Mathematics (AREA)
  • Fuzzy Systems (AREA)
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Abstract

La presente solicitud se refiere principalmente a métodos específicos para inferir la actividad de una vía de señalización celular en el tejido y/o las células de un sujeto médico con base por lo menos en los niveles de expresión de uno o más genes objetivo de la vía de señalización celular medios en una muestra extraída del tejido y/o las células del sujeto médico, aparato que comprende un compresor digital configurado para realizar estos métodos y un medio de almacenamiento no transitorio que almacena instrucciones que son ejecutables por dispositivo de procesamiento digital para realizar estos métodos.
MX2015008177A 2012-12-26 2013-12-18 Evaluacion de la actividad de la via de señalizacion celular utilizando combinacion(es) lineal(es) de expresiones de genes objetivo. MX2015008177A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261745839P 2012-12-26 2012-12-26
PCT/IB2013/061066 WO2014102668A2 (en) 2012-12-26 2013-12-18 Assessment of cellular signaling pathway activity using linear combination(s) of target gene expressions;

Publications (1)

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MX2015008177A true MX2015008177A (es) 2015-09-16

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MX2015008177A MX2015008177A (es) 2012-12-26 2013-12-18 Evaluacion de la actividad de la via de señalizacion celular utilizando combinacion(es) lineal(es) de expresiones de genes objetivo.

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US (2) US11306360B2 (es)
EP (1) EP2938745B1 (es)
JP (2) JP6449779B2 (es)
KR (1) KR102279844B1 (es)
CN (2) CN111961726A (es)
AU (2) AU2013368945B2 (es)
BR (1) BR112015015131A2 (es)
CA (1) CA2896414C (es)
DK (1) DK2938745T3 (es)
ES (1) ES2878196T3 (es)
MX (1) MX2015008177A (es)
RU (1) RU2721130C2 (es)
WO (1) WO2014102668A2 (es)

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CN108187050A (zh) * 2018-01-18 2018-06-22 石河子大学 抑制食管癌细胞增殖的药物
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CN111166884B (zh) * 2020-01-15 2021-12-03 广州中医药大学第一附属医院 Foxf1基因在制备用于骨质疏松症药物中的应用
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RU2015131009A (ru) 2017-01-30
DK2938745T3 (da) 2020-11-30
EP2938745B1 (en) 2020-10-07
CA2896414C (en) 2023-06-20
AU2020202706A1 (en) 2020-05-14
CN105074005A (zh) 2015-11-18
AU2020202706B2 (en) 2022-06-16
JP6449779B2 (ja) 2019-01-09
BR112015015131A2 (pt) 2017-07-11
RU2721130C2 (ru) 2020-05-18
US20150347672A1 (en) 2015-12-03
WO2014102668A3 (en) 2014-08-21
WO2014102668A2 (en) 2014-07-03
ES2878196T3 (es) 2021-11-18
JP6721665B2 (ja) 2020-07-15
JP2016509472A (ja) 2016-03-31
JP2019076096A (ja) 2019-05-23
EP2938745A2 (en) 2015-11-04
US20230030858A1 (en) 2023-02-02
CN111961726A (zh) 2020-11-20
CA2896414A1 (en) 2014-07-03
AU2013368945B2 (en) 2020-01-23
US11306360B2 (en) 2022-04-19
AU2013368945A1 (en) 2015-08-13
KR102279844B1 (ko) 2021-07-21
KR20150100896A (ko) 2015-09-02

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