MX2015007573A - Vacuna contra el tumor de wilms 1. - Google Patents

Vacuna contra el tumor de wilms 1.

Info

Publication number
MX2015007573A
MX2015007573A MX2015007573A MX2015007573A MX2015007573A MX 2015007573 A MX2015007573 A MX 2015007573A MX 2015007573 A MX2015007573 A MX 2015007573A MX 2015007573 A MX2015007573 A MX 2015007573A MX 2015007573 A MX2015007573 A MX 2015007573A
Authority
MX
Mexico
Prior art keywords
disclosed
mutated
antigen
nucleic acid
encode
Prior art date
Application number
MX2015007573A
Other languages
English (en)
Other versions
MX364732B (es
Inventor
David B Weiner
Jian Yan
Jewell Walters
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of MX2015007573A publication Critical patent/MX2015007573A/es
Publication of MX364732B publication Critical patent/MX364732B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

En la presente se describen moléculas de ácido nucleico que comprenden una o más secuencias de ácidos nucleicos que codifican un antígeno de WT1 mutado; se describen vectores, composiciones y vacunas que comprenden una o más secuencias de ácidos nucleicos que codifican un antígeno de WT1 mutado; se describen métodos para tratar a un individuo con un tumor que expresa WT1 y métodos para prevenir un tumor que expresa WT1; se describe un antígeno de WT1 mutado.
MX2015007573A 2012-12-13 2013-12-13 Vacuna contra el tumor de wilms 1. MX364732B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737094P 2012-12-13 2012-12-13
PCT/US2013/075141 WO2014093897A1 (en) 2012-12-13 2013-12-13 Wt1 vaccine

Publications (2)

Publication Number Publication Date
MX2015007573A true MX2015007573A (es) 2016-03-15
MX364732B MX364732B (es) 2019-05-06

Family

ID=50935008

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015007573A MX364732B (es) 2012-12-13 2013-12-13 Vacuna contra el tumor de wilms 1.

Country Status (13)

Country Link
US (3) US10220082B2 (es)
EP (2) EP3782640A1 (es)
JP (3) JP6523174B2 (es)
KR (3) KR20230038607A (es)
CN (1) CN104812401B (es)
AU (1) AU2013358947B2 (es)
BR (1) BR112015013004B1 (es)
CA (1) CA2888648C (es)
HK (1) HK1212919A1 (es)
MX (1) MX364732B (es)
PL (1) PL2931304T3 (es)
SI (1) SI2931304T1 (es)
WO (2) WO2014093897A1 (es)

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WO2015089492A2 (en) * 2013-12-13 2015-06-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
EP3226892A4 (en) 2014-12-01 2018-07-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
MX2020006216A (es) * 2017-12-13 2020-08-31 Inovio Pharmaceuticals Inc Vacunas contra el cancer dirigidas a prame y sus usos.
RU2760984C1 (ru) * 2017-12-13 2021-12-02 Иновио Фармасьютикалз, Инк. Противораковые вакцины, направленные на lemd1, и их применение
WO2023201199A2 (en) * 2022-04-11 2023-10-19 The Johns Hopkins University Tuberculosis vaccines
CN115845039A (zh) * 2022-07-01 2023-03-28 可蓝赛生物医药(上海)有限公司 一种广谱多肽肿瘤疫苗组成
CN116139260A (zh) * 2023-03-02 2023-05-23 广东龄值生物科技有限公司 一种wt1肿瘤疫苗及其制备方法与应用

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Also Published As

Publication number Publication date
HK1212919A1 (zh) 2016-06-24
KR20150096709A (ko) 2015-08-25
EP3782640A1 (en) 2021-02-24
KR102258021B1 (ko) 2021-06-01
CN104812401B (zh) 2017-10-13
WO2014093886A1 (en) 2014-06-19
BR112015013004A2 (pt) 2017-09-12
AU2013358947A1 (en) 2015-05-21
US10220082B2 (en) 2019-03-05
EP2931304A4 (en) 2016-07-20
US20230293653A1 (en) 2023-09-21
AU2013358947B2 (en) 2016-10-20
EP2931304B1 (en) 2021-04-28
SI2931304T1 (sl) 2021-11-30
BR112015013004B1 (pt) 2022-09-06
JP2016501536A (ja) 2016-01-21
JP2019115369A (ja) 2019-07-18
PL2931304T3 (pl) 2021-11-08
CN104812401A (zh) 2015-07-29
KR20210062748A (ko) 2021-05-31
MX364732B (es) 2019-05-06
JP2022048162A (ja) 2022-03-25
CA2888648C (en) 2021-06-08
WO2014093897A1 (en) 2014-06-19
JP7011241B2 (ja) 2022-01-26
CA2888648A1 (en) 2014-06-19
EP2931304A1 (en) 2015-10-21
AU2013358947A8 (en) 2015-05-28
US11638747B2 (en) 2023-05-02
KR20230038607A (ko) 2023-03-20
JP6523174B2 (ja) 2019-05-29
KR102509444B1 (ko) 2023-03-14
US20150328298A1 (en) 2015-11-19
US20190255163A1 (en) 2019-08-22

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