BR112015013004A2 - molécula de ácido nucleico isolada, composição, vacina, métodos de tratamento de um indivíduo e de prevenção de um tumor, proteína, e, peptídeo - Google Patents

molécula de ácido nucleico isolada, composição, vacina, métodos de tratamento de um indivíduo e de prevenção de um tumor, proteína, e, peptídeo

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Publication number
BR112015013004A2
BR112015013004A2 BR112015013004A BR112015013004A BR112015013004A2 BR 112015013004 A2 BR112015013004 A2 BR 112015013004A2 BR 112015013004 A BR112015013004 A BR 112015013004A BR 112015013004 A BR112015013004 A BR 112015013004A BR 112015013004 A2 BR112015013004 A2 BR 112015013004A2
Authority
BR
Brazil
Prior art keywords
nucleic acid
tumor
methods
treating
preventing
Prior art date
Application number
BR112015013004A
Other languages
English (en)
Other versions
BR112015013004B1 (pt
Inventor
B Weiner David
Yan Jian
walters Jewell
Original Assignee
The Trustees Of The Univ Of Pennsylvania E Inovio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Trustees Of The Univ Of Pennsylvania E Inovio Pharmaceuticals Inc filed Critical The Trustees Of The Univ Of Pennsylvania E Inovio Pharmaceuticals Inc
Publication of BR112015013004A2 publication Critical patent/BR112015013004A2/pt
Publication of BR112015013004B1 publication Critical patent/BR112015013004B1/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001152—Transcription factors, e.g. SOX or c-MYC
    • A61K39/001153—Wilms tumor 1 [WT1]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1 / 1 resumo “molã‰cula de ãcido nucleico isolada, composiã‡ãƒo, vacina, mã‰todos de tratamento de um indivãduo e de prevenã‡ãƒo de um tumor, proteãna, e, peptãdeo” neste documento sã£o divulgadas as molã©culas de ã¡cido nucleico caracterizadas por compreender uma ou mais sequãªncias de ã¡cidos nucleicos que codificam um antã­geno de wt1 mutante. os vetores, composiã§ãµes e vacinas compreendendo uma ou mais sequãªncias de ã¡cidos nucleicos que codificam um antã­geno de wt1 mutante sã£o divulgadas. os mã©todos para tratamento de um indivã­duo que possui um tumor que expressa wt1 e mã©todos de prevenã§ã£o de um tumor que expressa wt1 sã£o divulgados. o antã­geno de wt1 mutante ã© divulgado.
BR112015013004-6A 2012-12-13 2013-12-13 Molécula de ácido nucleico isolada, proteína e seus usos, bem como composição e vacina BR112015013004B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261737094P 2012-12-13 2012-12-13
US61/737,094 2012-12-13
PCT/US2013/075141 WO2014093897A1 (en) 2012-12-13 2013-12-13 Wt1 vaccine

Publications (2)

Publication Number Publication Date
BR112015013004A2 true BR112015013004A2 (pt) 2017-09-12
BR112015013004B1 BR112015013004B1 (pt) 2022-09-06

Family

ID=50935008

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015013004-6A BR112015013004B1 (pt) 2012-12-13 2013-12-13 Molécula de ácido nucleico isolada, proteína e seus usos, bem como composição e vacina

Country Status (13)

Country Link
US (3) US10220082B2 (pt)
EP (2) EP3782640A1 (pt)
JP (3) JP6523174B2 (pt)
KR (3) KR102258021B1 (pt)
CN (1) CN104812401B (pt)
AU (1) AU2013358947B2 (pt)
BR (1) BR112015013004B1 (pt)
CA (1) CA2888648C (pt)
HK (1) HK1212919A1 (pt)
MX (1) MX364732B (pt)
PL (1) PL2931304T3 (pt)
SI (1) SI2931304T1 (pt)
WO (2) WO2014093897A1 (pt)

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WO2015089492A2 (en) * 2013-12-13 2015-06-18 The Trustees Of The University Of Pennsylvania Dna antibody constructs and method of using same
AU2015355126B9 (en) 2014-12-01 2020-03-26 Inovio Pharmaceuticals, Inc. DNA antibody constructs and method of using same
MX2020006216A (es) * 2017-12-13 2020-08-31 Inovio Pharmaceuticals Inc Vacunas contra el cancer dirigidas a prame y sus usos.
US11338028B2 (en) * 2017-12-13 2022-05-24 Inovio Pharmaceuticals, Inc. Cancer vaccines targeting LEMD1 and uses thereof
WO2023201199A2 (en) * 2022-04-11 2023-10-19 The Johns Hopkins University Tuberculosis vaccines
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Also Published As

Publication number Publication date
US10220082B2 (en) 2019-03-05
HK1212919A1 (zh) 2016-06-24
JP2016501536A (ja) 2016-01-21
JP6523174B2 (ja) 2019-05-29
JP2019115369A (ja) 2019-07-18
EP3782640A1 (en) 2021-02-24
AU2013358947A1 (en) 2015-05-21
JP2022048162A (ja) 2022-03-25
CN104812401B (zh) 2017-10-13
PL2931304T3 (pl) 2021-11-08
CA2888648C (en) 2021-06-08
KR20230038607A (ko) 2023-03-20
KR102509444B1 (ko) 2023-03-14
AU2013358947A8 (en) 2015-05-28
US20150328298A1 (en) 2015-11-19
KR102258021B1 (ko) 2021-06-01
EP2931304A1 (en) 2015-10-21
MX2015007573A (es) 2016-03-15
JP7011241B2 (ja) 2022-01-26
US20230293653A1 (en) 2023-09-21
EP2931304B1 (en) 2021-04-28
CN104812401A (zh) 2015-07-29
BR112015013004B1 (pt) 2022-09-06
KR20150096709A (ko) 2015-08-25
EP2931304A4 (en) 2016-07-20
WO2014093886A1 (en) 2014-06-19
US20190255163A1 (en) 2019-08-22
SI2931304T1 (sl) 2021-11-30
MX364732B (es) 2019-05-06
US11638747B2 (en) 2023-05-02
WO2014093897A1 (en) 2014-06-19
KR20210062748A (ko) 2021-05-31
AU2013358947B2 (en) 2016-10-20
CA2888648A1 (en) 2014-06-19

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