MX2015006419A - Tratamiento de la intolerancia al gluten y padecimientos relacionados. - Google Patents

Tratamiento de la intolerancia al gluten y padecimientos relacionados.

Info

Publication number
MX2015006419A
MX2015006419A MX2015006419A MX2015006419A MX2015006419A MX 2015006419 A MX2015006419 A MX 2015006419A MX 2015006419 A MX2015006419 A MX 2015006419A MX 2015006419 A MX2015006419 A MX 2015006419A MX 2015006419 A MX2015006419 A MX 2015006419A
Authority
MX
Mexico
Prior art keywords
related conditions
treatment
gluten intolerance
nepenthesin
derivative
Prior art date
Application number
MX2015006419A
Other languages
English (en)
Inventor
David Schriemer
Martial Rey
Original Assignee
Nepetx Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nepetx Llc filed Critical Nepetx Llc
Publication of MX2015006419A publication Critical patent/MX2015006419A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/63Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from plants
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06Enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/23Aspartic endopeptidases (3.4.23)
    • C12Y304/23012Nepenthesin (3.4.23.12)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

En este documento se proporcionan composiciones, alimentos que comprenden nepentesina o un derivado de la misma, y métodos para utilizar la nepentesina o su derivado para modular la intolerancia al gluten y padecimientos relacionados, tales como la celiaquía.
MX2015006419A 2012-11-21 2013-11-20 Tratamiento de la intolerancia al gluten y padecimientos relacionados. MX2015006419A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261729210P 2012-11-21 2012-11-21
US201261797040P 2012-11-27 2012-11-27
PCT/CA2013/000970 WO2014078935A1 (en) 2012-11-21 2013-11-20 Treatment of gluten intolerance and related conditions

Publications (1)

Publication Number Publication Date
MX2015006419A true MX2015006419A (es) 2015-12-15

Family

ID=50728145

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015006419A MX2015006419A (es) 2012-11-21 2013-11-20 Tratamiento de la intolerancia al gluten y padecimientos relacionados.
MX2015011825A MX2015011825A (es) 2012-11-21 2014-03-14 Tratamiento de la intolerancia al gluten y padecimientos relacionados.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2015011825A MX2015011825A (es) 2012-11-21 2014-03-14 Tratamiento de la intolerancia al gluten y padecimientos relacionados.

Country Status (15)

Country Link
US (7) US9005610B2 (es)
EP (1) EP2922568A1 (es)
JP (1) JP6412876B2 (es)
KR (1) KR102296428B1 (es)
CN (1) CN105007934B (es)
AU (1) AU2013350261B2 (es)
CA (1) CA2892474C (es)
DK (1) DK3004340T3 (es)
ES (1) ES2821771T3 (es)
HR (1) HRP20201459T1 (es)
HU (1) HUE050868T2 (es)
IL (2) IL238912B (es)
MX (2) MX2015006419A (es)
PT (1) PT3004340T (es)
WO (2) WO2014078935A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9005610B2 (en) 2012-11-21 2015-04-14 Nepetx, Llc Treatment of gluten intolerance and related conditions
KR102476601B1 (ko) * 2013-03-15 2022-12-13 네페택스, 엘엘씨 글루텐 불내증 및 관련 질병의 치료
SI3220946T1 (sl) * 2014-06-16 2021-11-30 Codexis, Inc. Sestave in metode za lajšanje in preprečevanje vnetja črevesja zaradi prisotnosti antigenov peptidnih živil v črevesu
WO2017106798A2 (en) * 2015-12-16 2017-06-22 Nepetx, Llc Compositions and methods for treating gluten intolerance and disorders arising therefrom
AU2018335849B2 (en) * 2017-09-20 2023-04-13 Aarhus Universitet Nepenthesin-1 derived resistance to fungal pathogens in major crop plants
EA202192668A1 (ru) * 2019-04-02 2022-02-07 Сами-Сабинса Груп Лимитед Способ и композиция для терапевтического лечения непереносимости глютена

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK81193D0 (da) * 1993-07-06 1993-07-06 Novo Nordisk As Enzym
JP3767831B2 (ja) * 1995-06-14 2006-04-19 木村 健 ヘリコバクター・ピロリ除菌用組成物
JP3521635B2 (ja) 1996-08-07 2004-04-19 日本電信電話株式会社 映像生成方法および映像生成システム
JPH1149697A (ja) * 1997-08-01 1999-02-23 Nisshin Flour Milling Co Ltd ストレス抑制剤及びストレス抑制用食品
DE60336754D1 (de) 2002-02-14 2011-05-26 Univ R Enzymbehandlung von nahrungsmitteln für zöliakie-sprue
US7320788B2 (en) * 2002-02-14 2008-01-22 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for Celiac Sprue
US8143210B2 (en) 2002-02-14 2012-03-27 The Board Of Trustees Of The Leland Stanford Junior University Enzyme treatment of foodstuffs for celiac sprue
JP4415244B2 (ja) * 2003-02-21 2010-02-17 グリコ栄養食品株式会社 小麦蛋白質にプロテアーゼを限定的に作用させて得られる食品素材
US7628985B2 (en) 2004-04-26 2009-12-08 The Board Of Regents Of The Leland Stanford Junior University Therapeutic enzyme formulations and uses thereof in celiac sprue and/or dermatitis herpetoformis
US20060095096A1 (en) 2004-09-09 2006-05-04 Debenedictis Leonard C Interchangeable tips for medical laser treatments and methods for using same
EP1856291A4 (en) 2005-03-04 2009-04-01 Verenium Corp NUCLEIC ACIDS AND PROTEINS, AND METHODS OF MAKING AND USING SAME
DK2272375T3 (da) * 2005-10-11 2014-01-13 Mofin S R L "Glutenfrie" blåskimmel-mejeriprodukter til personer, der lider af cøliaki
WO2007044906A2 (en) 2005-10-11 2007-04-19 Alvine Pharmaceuticals, Inc. Compositions and methods for enhanced gastrointestinal stability of oligopeptides and polypeptides
CA2644273A1 (en) 2006-04-05 2008-03-27 Metanomics Gmbh Process for the production of a fine chemical
WO2008115428A2 (en) 2007-03-16 2008-09-25 The Board Of Trustees Of The Leland Stanford Junior University A scaleable manufacturing process for cysteine endoprotease b, isoform 2
US20100322912A1 (en) * 2007-12-10 2010-12-23 Chaitan Khosla Combination Enzyme Therapy for Gastric Digestion of Dietary Gluten in Celiac Sprue Patients
CA2733514C (en) 2008-08-21 2017-10-24 Alvine Pharmaceuticals, Inc. Formulation for oral administration of proteins
JP2011049697A (ja) 2009-08-25 2011-03-10 Panasonic Corp フリッカ検出装置、撮像装置、フリッカ検出プログラム、及び、フリッカ検出方法
US20110200574A1 (en) 2010-02-02 2011-08-18 Jolly James F Use of proteases for gluten intolerance
WO2011126873A2 (en) 2010-03-30 2011-10-13 Alvine Pharmaceuticals, Inc. Proteases for degrading gluten
US9023345B2 (en) * 2011-03-01 2015-05-05 Novus International, Inc. Methods for improving gut health
US9005610B2 (en) 2012-11-21 2015-04-14 Nepetx, Llc Treatment of gluten intolerance and related conditions

Also Published As

Publication number Publication date
CN105007934B (zh) 2019-02-05
IL283484A (en) 2021-06-30
US9745565B2 (en) 2017-08-29
EP2922568A1 (en) 2015-09-30
US20150290301A1 (en) 2015-10-15
IL238912B (en) 2021-06-30
CN105007934A (zh) 2015-10-28
DK3004340T3 (da) 2020-09-21
US11725198B2 (en) 2023-08-15
JP6412876B2 (ja) 2018-10-24
US10266818B2 (en) 2019-04-23
AU2013350261A1 (en) 2015-07-09
US20200040322A1 (en) 2020-02-06
WO2014078935A1 (en) 2014-05-30
HRP20201459T1 (hr) 2020-12-11
US20140186330A1 (en) 2014-07-03
IL238912A0 (en) 2015-07-30
US20150265686A1 (en) 2015-09-24
US20170067040A1 (en) 2017-03-09
US9623092B2 (en) 2017-04-18
CA2892474A1 (en) 2014-05-30
MX2015011825A (es) 2016-05-31
WO2014138927A1 (en) 2014-09-18
US10982201B2 (en) 2021-04-20
JP2016501853A (ja) 2016-01-21
CA2892474C (en) 2022-06-21
AU2013350261B2 (en) 2018-12-06
KR102296428B1 (ko) 2021-09-01
KR20150123783A (ko) 2015-11-04
PT3004340T (pt) 2020-09-30
US20140140980A1 (en) 2014-05-22
HUE050868T2 (hu) 2021-01-28
ES2821771T3 (es) 2021-04-27
US9005610B2 (en) 2015-04-14
US20210230569A1 (en) 2021-07-29

Similar Documents

Publication Publication Date Title
PH12019502292A1 (en) Methods and compositions for treatment of a genetic condition
AU2019232913A1 (en) Methods and processes for non-invasive assessment of genetic variations
PH12018501711A1 (en) Compounds for treating spinal muscular atrophy
PH12015501720B1 (en) Modulators of methyl modifying enzymes, compositions and uses thereof
CA2877331C (en) Methods and processes for non-invasive assessment of genetic variations
MY172156A (en) Modulators of methyl modifying enzymes, compositions and uses thereof
CA2865011C (en) Methods and compositions for treating huntington's disease
AU2013225816A8 (en) Compositions and methods for treating Type III Gaucher Disease
MX357834B (es) Compuestos de tipo isocumarina sustituidos para tratar la atrofia muscular espinal.
MX352962B (es) Compuestos para tratar atrofia muscular espinal.
MX358514B (es) Compuestos para tratar la atrofia muscular espinal.
MX2015003874A (es) Modulacion de ire1.
NZ628294A (en) Compositions and methods of use of phorbol esters for the treatment of stroke
MX359769B (es) Metodos para descelularizar huesos.
MX2015006419A (es) Tratamiento de la intolerancia al gluten y padecimientos relacionados.
IN2014KN02620A (es)
GB2498325A (en) Modulation neural pathways
EP4023243A3 (en) Compositions and methods for treating celiac sprue disease
MX2014009750A (es) Composiciones antifungicas para el tratamiento de piel y uñas.
MX2016004393A (es) Derivados de carboxamida como compuestos pesticidas.
EP2948170A4 (en) METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING C LIAK DISEASE AND GLUTEN INTOLERANCE
EP3220946A4 (en) Compositions and methods for treating gluten intolerance and disorders arising therefrom
GEP201706708B (en) Isoxazolidine derivatives
EP3220940A4 (en) Compositions and methods for modulating at2r activity
PH12017501147A1 (en) Total synthesis of trioxacarcin dc-45-a2 and preparation of trioxacarcin analogs