MX2015006357A - Parche de dias multiples para la administracion transdermica de rotigotina. - Google Patents

Parche de dias multiples para la administracion transdermica de rotigotina.

Info

Publication number
MX2015006357A
MX2015006357A MX2015006357A MX2015006357A MX2015006357A MX 2015006357 A MX2015006357 A MX 2015006357A MX 2015006357 A MX2015006357 A MX 2015006357A MX 2015006357 A MX2015006357 A MX 2015006357A MX 2015006357 A MX2015006357 A MX 2015006357A
Authority
MX
Mexico
Prior art keywords
rotigotine
transdermal therapeutic
present
therapeutic system
self
Prior art date
Application number
MX2015006357A
Other languages
English (en)
Other versions
MX354502B (es
Inventor
Willi Cawello
Aurelia Lappert
Kristina Kassner
Hans-Michael Wolff
Walter Müller
Johannes Josef Leonhard
Marco Emgenbroich
Original Assignee
Ucb Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47215446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2015006357(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ucb Pharma Gmbh filed Critical Ucb Pharma Gmbh
Publication of MX2015006357A publication Critical patent/MX2015006357A/es
Publication of MX354502B publication Critical patent/MX354502B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B37/00—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding
    • B32B37/12—Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by using adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2556/00—Patches, e.g. medical patches, repair patches

Abstract

La presente invención se refiere a un sistema terapéutico transdérmico, que comprende (a) una capa de respaldo, (b) una capa de matriz auto-adhesiva basada en solvente que contiene rotigotina como ingrediente activo, y (c) un revestimiento de liberación, en donde la capa de matriz auto-adhesiva tiene un peso de recubrimiento de alrededor de 75-400 g/m2 y comprende una capa de reservorio que contiene alrededor de 9-25% en peso de rotigotina basado en el peso de la capa de reservorio, un kit que comprende dos sistemas terapéuticos transdérmicos de la presente invención así como un método para la preparación del sistema terapéutico transdérmico de la presente invención. Además, la presente invención se refiere a un sistema terapéutico transdérmico que comprende rotigotina como ingrediente activo para uso en el tratamiento de pacientes que padecen de mal de Parkinson, síndrome de Parkinson adicional, depresión, fibromialgia y el síndrome de piernas inquietas y para uso en el tratamiento o prevención de pérdida de neurona dopaminérgica o trastornos cognitivos por administración transdérmica de rotigotina una vez o dos veces a la semana, en donde el sistema terapéutico transdérmico comprende una capa de respaldo, una capa de matriz auto-adhesiva que contiene rotigotina basado en solvente así como un revestimiento de liberación y se adapta para permitir la administración transdérmica de cantidades terapéuticamente efectivas de rotigotina durante al menos 3 días.
MX2015006357A 2012-11-22 2013-11-21 Parche de dias multiples para la administracion transdermica de rotigotina. MX354502B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12193808 2012-11-22
PCT/EP2013/003515 WO2014079573A1 (en) 2012-11-22 2013-11-21 Multi-day patch for the transdermal administration of rotigotine

Publications (2)

Publication Number Publication Date
MX2015006357A true MX2015006357A (es) 2016-02-10
MX354502B MX354502B (es) 2018-03-08

Family

ID=47215446

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015006357A MX354502B (es) 2012-11-22 2013-11-21 Parche de dias multiples para la administracion transdermica de rotigotina.

Country Status (15)

Country Link
US (2) US11389410B2 (es)
EP (1) EP2922533B1 (es)
JP (1) JP6301356B2 (es)
KR (1) KR20150094588A (es)
CN (2) CN110200950B (es)
AR (1) AR093481A1 (es)
AU (1) AU2013350037B2 (es)
BR (1) BR112015011729B1 (es)
CA (1) CA2887085C (es)
EA (1) EA201500553A1 (es)
ES (1) ES2639294T3 (es)
IN (1) IN2015DN02488A (es)
MX (1) MX354502B (es)
TW (1) TW201431570A (es)
WO (1) WO2014079573A1 (es)

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CN104736146B (zh) 2019-03-01
US20220151949A1 (en) 2022-05-19
AU2013350037A1 (en) 2015-06-11
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US11389410B2 (en) 2022-07-19
EA201500553A1 (ru) 2015-12-30
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CN104736146A (zh) 2015-06-24
TW201431570A (zh) 2014-08-16
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CA2887085A1 (en) 2014-05-30
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CN104736146B9 (zh) 2019-04-12
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