MX2015002637A - Metodo para diagnostico de cancer. - Google Patents

Metodo para diagnostico de cancer.

Info

Publication number
MX2015002637A
MX2015002637A MX2015002637A MX2015002637A MX2015002637A MX 2015002637 A MX2015002637 A MX 2015002637A MX 2015002637 A MX2015002637 A MX 2015002637A MX 2015002637 A MX2015002637 A MX 2015002637A MX 2015002637 A MX2015002637 A MX 2015002637A
Authority
MX
Mexico
Prior art keywords
specimen
target gene
cancer
methylation status
present
Prior art date
Application number
MX2015002637A
Other languages
English (en)
Inventor
Hungcheng Lai
Original Assignee
Nat Defense Medical Ct
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Defense Medical Ct filed Critical Nat Defense Medical Ct
Publication of MX2015002637A publication Critical patent/MX2015002637A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

En la presente invención se da a conocer un método para diagnosticar cáncer, que comprende las siguientes etapas: (1) proporcionar un espécimen a detectarse; (2) detectar el estatus de metilación de la secuencia CpG de por lo menos un gen objetivo que es por lo menos uno de ADRA1D, AJAP1, HS3ST2, MAGI2, POU4F2, POU4F3, PTGDR, SOX17 y SYT9 en el DNA genómíco del espécimen; (3) determinar si se presenta cáncer o lesiones precancerosas en el espécimen de acuerdo con el estatus de metilación de por lo menos un gen objetivo.
MX2015002637A 2012-08-31 2012-08-31 Metodo para diagnostico de cancer. MX2015002637A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2012/001211 WO2014032205A1 (zh) 2012-08-31 2012-08-31 一种癌症筛检的方法

Publications (1)

Publication Number Publication Date
MX2015002637A true MX2015002637A (es) 2015-11-23

Family

ID=50182336

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002637A MX2015002637A (es) 2012-08-31 2012-08-31 Metodo para diagnostico de cancer.

Country Status (15)

Country Link
US (2) US10221458B2 (es)
EP (1) EP2891720B1 (es)
JP (1) JP2015526096A (es)
KR (1) KR20150067151A (es)
CN (1) CN105579590A (es)
AU (1) AU2012388616A1 (es)
BR (1) BR112015004423A8 (es)
CA (1) CA2883671A1 (es)
HU (1) HUE049697T2 (es)
IL (1) IL237436A0 (es)
MX (1) MX2015002637A (es)
PH (1) PH12015500430A1 (es)
RU (1) RU2700088C2 (es)
SG (1) SG11201501465SA (es)
WO (1) WO2014032205A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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EP2891720B1 (en) 2012-08-31 2020-04-08 National Defense Medical Center Method for screening cancer
CN106661572A (zh) * 2014-08-18 2017-05-10 和光纯药工业株式会社 癌症标志物及癌症的判定方法
JP6709541B2 (ja) * 2014-10-17 2020-06-17 国立大学法人東北大学 大腸癌に対する薬物療法の感受性を予測する方法
JP6655243B2 (ja) * 2015-09-01 2020-02-26 国立大学法人 鹿児島大学 口腔前癌病変の検出方法
WO2017067477A1 (en) * 2015-10-20 2017-04-27 Hung-Cheng Lai Methods for making diagnosis and/or prognosis of gynecologic neoplasm
WO2018008153A1 (ja) * 2016-07-08 2018-01-11 有限会社ハヌマット 大腸癌発症可能性の判定方法
GB201703406D0 (en) * 2017-03-02 2017-04-19 Ucl Business Plc Diagnostic and prognostic methods
CN109234378A (zh) * 2018-09-27 2019-01-18 中国航天员科研训练中心 预测失重骨丢失骨钙素oc下降风险的方法与dna甲基化标志物
WO2020116573A1 (ja) * 2018-12-05 2020-06-11 学校法人慶應義塾 子宮体癌の予後の判定方法
JP2023539128A (ja) * 2020-08-19 2023-09-13 マヨ ファウンデーション フォア メディカル エデュケーション アンド リサーチ 非ホジキンリンパ腫の検出
CN114540489B (zh) * 2020-11-27 2024-01-30 广州达健生物科技有限公司 一种宫颈癌早期筛查检测试剂盒及其应用
EP4130297A1 (en) * 2021-08-05 2023-02-08 Beijing OriginPoly Bio-Tec Co., Ltd. Markers, primers, probes and kit for early screening and diagnosis of endometrial cancer
CN113337614A (zh) * 2021-08-05 2021-09-03 北京起源聚禾生物科技有限公司 子宫内膜癌早期筛查诊断用标志物、引物探针及试剂盒

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DE10112515B4 (de) * 2001-03-09 2004-02-12 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität
US7461163B2 (en) 2002-08-16 2008-12-02 Infrastructure Innovations Llc Real time mesh measurement system stream latency and jitter measurements
US20100273151A1 (en) 2004-05-28 2010-10-28 Fred Hutchinson Cancer Research Center Genome-wide analysis of palindrome formation and dna methylation
ES2533767T3 (es) * 2005-04-15 2015-04-15 Epigenomics Ag Métodos para el análisis de trastornos proliferativos celulares
GB0700374D0 (en) 2007-01-09 2007-02-14 Oncomethylome Sciences S A NDRG family methylation markers
TW200831900A (en) 2007-01-23 2008-08-01 Hong-Zheng Lai Cancer screen method
JP2010517582A (ja) * 2007-02-12 2010-05-27 ザ・ジョンズ・ホプキンス・ユニバーシティー 結腸癌の早期検出および予後診断の方法
US7820386B2 (en) 2007-06-15 2010-10-26 National Defense Medical Center Cancer screening method
JP2009005621A (ja) 2007-06-28 2009-01-15 Fujifilm Corp 神経芽腫の悪性度を含めた検出方法、及び抑制方法
EP2677041A3 (en) 2008-02-19 2014-04-09 MDxHealth SA Detection and prognosis of lung cancer
CN101970692B (zh) * 2008-03-14 2017-02-01 基因特力株式会社 使用肺癌特异性甲基化标记基因检测肺癌的方法
EP2626435B1 (en) 2008-03-21 2016-06-01 MDxHealth S.A. Detection and prognosis of cervical cancer
CN105586408B (zh) * 2008-04-29 2021-03-23 赖鸿政 一种癌症筛检的方法
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TWI385252B (zh) 2009-04-16 2013-02-11 Nat Defense Medical Ct 一種癌症篩檢的方法
RU2405837C1 (ru) * 2009-07-06 2010-12-10 Государственное образовательное учреждение высшего профессионального образования Московская медицинская академия им. И.М. Сеченова Федерального агентства по здравоохранению и социальному развитию (ГОУВПО ММА им. И.М. Сеченова Росздрава) Способ ранней днк-диагностики рака предстательной железы
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GB201102014D0 (en) 2011-02-04 2011-03-23 Ucl Business Plc Method for predicting risk of developing cancer
US20130041047A1 (en) 2011-06-01 2013-02-14 Aros Applied Biotechnology As Urinary Methylation Markers for Bladder Cancer
WO2012174256A2 (en) 2011-06-17 2012-12-20 The Regents Of The University Of Michigan Dna methylation profiles in cancer
JP2014525269A (ja) 2011-08-30 2014-09-29 ディーシービー−ユーエスエー エルエルシー 卵巣新生物に対する易罹患性及び／又は卵巣がんの予後若しくは悪性度を予測する方法
EP2891720B1 (en) 2012-08-31 2020-04-08 National Defense Medical Center Method for screening cancer

Also Published As

Publication number Publication date
BR112015004423A2 (pt) 2017-08-08
AU2012388616A1 (en) 2015-04-02
EP2891720A1 (en) 2015-07-08
WO2014032205A1 (zh) 2014-03-06
IL237436A0 (en) 2015-04-30
CN105579590A (zh) 2016-05-11
US20190136330A1 (en) 2019-05-09
EP2891720A4 (en) 2016-11-09
US20150361502A1 (en) 2015-12-17
KR20150067151A (ko) 2015-06-17
PH12015500430A1 (en) 2015-04-20
SG11201501465SA (en) 2015-05-28
US10221458B2 (en) 2019-03-05
CA2883671A1 (en) 2014-03-06
EP2891720B1 (en) 2020-04-08
BR112015004423A8 (pt) 2019-01-29
HUE049697T2 (hu) 2020-10-28
RU2700088C2 (ru) 2019-09-12
JP2015526096A (ja) 2015-09-10
RU2015111627A (ru) 2016-10-20

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