MX2015000315A - Anticuerpos anti-cd22 e inmunoconjugados. - Google Patents
Anticuerpos anti-cd22 e inmunoconjugados.Info
- Publication number
- MX2015000315A MX2015000315A MX2015000315A MX2015000315A MX2015000315A MX 2015000315 A MX2015000315 A MX 2015000315A MX 2015000315 A MX2015000315 A MX 2015000315A MX 2015000315 A MX2015000315 A MX 2015000315A MX 2015000315 A MX2015000315 A MX 2015000315A
- Authority
- MX
- Mexico
- Prior art keywords
- antibodies
- immunoconjugates
- methods
- same
- covalently attached
- Prior art date
Links
- 229940127121 immunoconjugate Drugs 0.000 title abstract 2
- CTMCWCONSULRHO-UHQPFXKFSA-N nemorubicin Chemical class C1CO[C@H](OC)CN1[C@@H]1[C@H](O)[C@H](C)O[C@@H](O[C@@H]2C3=C(O)C=4C(=O)C5=C(OC)C=CC=C5C(=O)C=4C(O)=C3C[C@](O)(C2)C(=O)CO)C1 CTMCWCONSULRHO-UHQPFXKFSA-N 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
- A61K47/6809—Antibiotics, e.g. antitumor antibiotics anthracyclins, adriamycin, doxorubicin or daunomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
- A61K47/6867—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from a cell of a blood cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261669269P | 2012-07-09 | 2012-07-09 | |
| US201261726738P | 2012-11-15 | 2012-11-15 | |
| PCT/US2013/049518 WO2014011520A1 (en) | 2012-07-09 | 2013-07-08 | Immunoconjugates comprising anti-cd22 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2015000315A true MX2015000315A (es) | 2015-07-06 |
Family
ID=48803623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015000315A MX2015000315A (es) | 2012-07-09 | 2013-07-08 | Anticuerpos anti-cd22 e inmunoconjugados. |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20140030281A1 (enExample) |
| EP (1) | EP2869851A1 (enExample) |
| JP (1) | JP6297549B2 (enExample) |
| KR (1) | KR20150030754A (enExample) |
| CN (1) | CN104428007B (enExample) |
| AR (1) | AR091701A1 (enExample) |
| AU (1) | AU2013288931A1 (enExample) |
| BR (1) | BR112015000439A2 (enExample) |
| CA (1) | CA2874904A1 (enExample) |
| CL (1) | CL2015000031A1 (enExample) |
| CO (1) | CO7151529A2 (enExample) |
| CR (1) | CR20150047A (enExample) |
| EA (1) | EA201590173A1 (enExample) |
| HK (1) | HK1207973A1 (enExample) |
| IL (1) | IL235987A0 (enExample) |
| MX (1) | MX2015000315A (enExample) |
| PE (1) | PE20150325A1 (enExample) |
| PH (1) | PH12014502825A1 (enExample) |
| SG (1) | SG11201500142RA (enExample) |
| TW (1) | TW201408696A (enExample) |
| WO (1) | WO2014011520A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2013364065B2 (en) | 2012-12-21 | 2018-10-04 | Altrubio Inc. | Hydrophilic self-immolative linkers and conjugates thereof |
| TWI636792B (zh) | 2013-08-12 | 2018-10-01 | 建南德克公司 | 1-(氯甲基)-2,3-二氫-1h-苯并[e]吲哚二聚體抗體-藥物結合物化合物及使用與治療方法 |
| MX2016007578A (es) | 2013-12-16 | 2016-10-03 | Genentech Inc | Compuestos de conjugado anticuerpo-farmaco dimerico de 1-(clorometil)-2,3-dihidro-1h-benzo [e] indol, y metodos de uso y tratamiento. |
| KR102206054B1 (ko) * | 2014-05-09 | 2021-01-21 | 삼성전자주식회사 | 지문 처리 방법 및 그 전자 장치 |
| GB201409558D0 (en) | 2014-05-29 | 2014-07-16 | Ucb Biopharma Sprl | Method |
| AR100919A1 (es) * | 2014-06-20 | 2016-11-09 | Bioalliance Cv | Conjugados de fármaco-anticuerpo anti-cd22 y métodos de uso de los mismos |
| RU2017101662A (ru) | 2014-06-20 | 2018-07-23 | Биоэллаенс К.В. | Конъюгаты антитела против фолатного рецептора альфа (fra) c лекарственным средством и способы их применения |
| GB201412659D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| GB201412658D0 (en) | 2014-07-16 | 2014-08-27 | Ucb Biopharma Sprl | Molecules |
| KR20170086121A (ko) * | 2014-12-03 | 2017-07-25 | 제넨테크, 인크. | 4급 아민 화합물 및 그의 항체-약물 접합체 |
| US10270724B2 (en) * | 2015-03-02 | 2019-04-23 | Pismo Labs Technology Limited | Methods and systems for processing messages at a multi-SIM network node |
| GB201601077D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibody molecule |
| GB201601073D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies |
| GB201601075D0 (en) | 2016-01-20 | 2016-03-02 | Ucb Biopharma Sprl | Antibodies molecules |
| GB201521382D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521383D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl And Ucb Celltech | Method |
| GB201521391D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| GB201521389D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Method |
| GB201521393D0 (en) | 2015-12-03 | 2016-01-20 | Ucb Biopharma Sprl | Antibodies |
| RU2766000C2 (ru) | 2016-01-08 | 2022-02-07 | АльтруБио Инк. | Четырехвалентные антитела к psgl-1 и их применения |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| CA3168654A1 (en) * | 2020-01-22 | 2021-07-29 | Shanghai Senhui Medicine Co., Ltd. | Drug conjugate of eribulin derivative, preparation method therefor and application thereof in medicine |
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-
2013
- 2013-07-08 BR BR112015000439A patent/BR112015000439A2/pt not_active IP Right Cessation
- 2013-07-08 CA CA2874904A patent/CA2874904A1/en not_active Abandoned
- 2013-07-08 PE PE2015000031A patent/PE20150325A1/es not_active Application Discontinuation
- 2013-07-08 CN CN201380036640.1A patent/CN104428007B/zh not_active Expired - Fee Related
- 2013-07-08 EP EP13739333.6A patent/EP2869851A1/en not_active Withdrawn
- 2013-07-08 KR KR20157003034A patent/KR20150030754A/ko not_active Withdrawn
- 2013-07-08 HK HK15108627.7A patent/HK1207973A1/xx unknown
- 2013-07-08 TW TW102124400A patent/TW201408696A/zh unknown
- 2013-07-08 EA EA201590173A patent/EA201590173A1/ru unknown
- 2013-07-08 AR ARP130102423 patent/AR091701A1/es unknown
- 2013-07-08 US US13/936,284 patent/US20140030281A1/en not_active Abandoned
- 2013-07-08 AU AU2013288931A patent/AU2013288931A1/en not_active Abandoned
- 2013-07-08 JP JP2015521676A patent/JP6297549B2/ja not_active Expired - Fee Related
- 2013-07-08 MX MX2015000315A patent/MX2015000315A/es unknown
- 2013-07-08 SG SG11201500142RA patent/SG11201500142RA/en unknown
- 2013-07-08 WO PCT/US2013/049518 patent/WO2014011520A1/en not_active Ceased
-
2014
- 2014-11-28 CO CO14262529A patent/CO7151529A2/es unknown
- 2014-11-30 IL IL235987A patent/IL235987A0/en unknown
- 2014-12-18 PH PH12014502825A patent/PH12014502825A1/en unknown
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2015
- 2015-01-07 CL CL2015000031A patent/CL2015000031A1/es unknown
- 2015-02-04 CR CR20150047A patent/CR20150047A/es unknown
-
2017
- 2017-04-26 US US15/497,636 patent/US20170326248A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CO7151529A2 (es) | 2014-12-29 |
| JP2015527319A (ja) | 2015-09-17 |
| CL2015000031A1 (es) | 2015-02-27 |
| AU2013288931A2 (en) | 2015-07-02 |
| BR112015000439A2 (pt) | 2017-12-19 |
| AU2013288931A1 (en) | 2014-12-11 |
| US20140030281A1 (en) | 2014-01-30 |
| PH12014502825A1 (en) | 2015-02-02 |
| CN104428007B (zh) | 2018-03-16 |
| AR091701A1 (es) | 2015-02-25 |
| EA201590173A1 (ru) | 2015-09-30 |
| CN104428007A (zh) | 2015-03-18 |
| JP6297549B2 (ja) | 2018-03-20 |
| WO2014011520A1 (en) | 2014-01-16 |
| US20170326248A1 (en) | 2017-11-16 |
| EP2869851A1 (en) | 2015-05-13 |
| PE20150325A1 (es) | 2015-03-05 |
| HK1207973A1 (en) | 2016-02-19 |
| IL235987A0 (en) | 2015-01-29 |
| CR20150047A (es) | 2015-03-23 |
| TW201408696A (zh) | 2014-03-01 |
| SG11201500142RA (en) | 2015-02-27 |
| CA2874904A1 (en) | 2014-01-16 |
| KR20150030754A (ko) | 2015-03-20 |
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