MX2014011786A - Uso de inhibidores de ccr3. - Google Patents

Uso de inhibidores de ccr3.

Info

Publication number
MX2014011786A
MX2014011786A MX2014011786A MX2014011786A MX2014011786A MX 2014011786 A MX2014011786 A MX 2014011786A MX 2014011786 A MX2014011786 A MX 2014011786A MX 2014011786 A MX2014011786 A MX 2014011786A MX 2014011786 A MX2014011786 A MX 2014011786A
Authority
MX
Mexico
Prior art keywords
eosinophilic
alkyl
age
macular degeneration
ccr3 inhibitors
Prior art date
Application number
MX2014011786A
Other languages
English (en)
Spanish (es)
Inventor
Thierry Bouyssou
Rolf Goeggel
Peter Seither
Michael Chadham Nivens
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48040249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2014011786(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2014011786A publication Critical patent/MX2014011786A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Structure Of Transmissions (AREA)
MX2014011786A 2012-04-03 2013-04-02 Uso de inhibidores de ccr3. MX2014011786A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12162937 2012-04-03
PCT/EP2013/056864 WO2013149986A1 (en) 2012-04-03 2013-04-02 Use of ccr3-inhibitors

Publications (1)

Publication Number Publication Date
MX2014011786A true MX2014011786A (es) 2014-12-05

Family

ID=48040249

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014011786A MX2014011786A (es) 2012-04-03 2013-04-02 Uso de inhibidores de ccr3.

Country Status (28)

Country Link
US (5) US20130261153A1 (OSRAM)
EP (3) EP3763369B1 (OSRAM)
JP (2) JP2015512432A (OSRAM)
KR (5) KR20200044988A (OSRAM)
CN (2) CN104220073A (OSRAM)
AU (1) AU2013245027B2 (OSRAM)
BR (1) BR112014023795B1 (OSRAM)
CA (1) CA2869269C (OSRAM)
CL (1) CL2014002523A1 (OSRAM)
CY (1) CY1123222T1 (OSRAM)
DK (1) DK2833884T3 (OSRAM)
EA (1) EA032263B1 (OSRAM)
ES (2) ES2811554T3 (OSRAM)
HR (1) HRP20201165T1 (OSRAM)
HU (1) HUE051648T2 (OSRAM)
IL (1) IL234262A (OSRAM)
IN (1) IN2014DN06989A (OSRAM)
LT (1) LT2833884T (OSRAM)
MX (1) MX2014011786A (OSRAM)
NZ (1) NZ628882A (OSRAM)
PH (1) PH12014502239A1 (OSRAM)
PL (1) PL2833884T3 (OSRAM)
PT (1) PT2833884T (OSRAM)
RS (1) RS60665B1 (OSRAM)
SI (1) SI2833884T1 (OSRAM)
SM (1) SMT202000499T1 (OSRAM)
WO (1) WO2013149986A1 (OSRAM)
ZA (1) ZA201406082B (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US8680280B2 (en) 2012-04-02 2014-03-25 Boehringer Ingelheim International Gmbh Process for the manufacturing of CRR inhibitors
US20130261153A1 (en) * 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
CN109310486B (zh) 2016-11-24 2021-07-02 雾岛精工株式会社 齿列矫正器和齿列矫正器的安装方法
EP3606521B1 (en) * 2017-04-05 2023-04-19 Alkahest, Inc. Compounds and pharmaceutical compositions for use in treating retina-associated disease using ccr3-inhibitors
MX394341B (es) 2017-04-05 2025-03-24 Alkahest Inc Metodos y composiciones para tratar deterioros asociados con el envejecimiento usando inhibidores de ccr3
CA3076017A1 (en) * 2017-10-13 2019-04-18 Alkahest, Inc. Methods and compositions for treating pruritus, xerosis, and associated disease using ccr3-inhibitors
SG11202010115RA (en) 2018-05-15 2020-11-27 Alkahest Inc Treatment of aging-associated disease with modulators of leukotriene a4 hydrolase
EA202190463A1 (ru) * 2018-09-26 2021-06-29 Алкахест, Инк. Способы и композиции для лечения ассоциированных со старением нарушений с применением ccr3-ингибиторов
WO2021252647A1 (en) * 2020-06-11 2021-12-16 Alkahest Inc. Methods of improving retina-associated disease outcome using ccr3-inhibitors
AU2022376563A1 (en) 2021-11-01 2023-12-07 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6339087B1 (en) * 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
ATE414151T1 (de) * 2000-03-03 2008-11-15 Cambridge Antibody Tech Antikörper gegen eotaxin und deren verwendung
US20020151064A1 (en) * 2001-02-07 2002-10-17 Children's Hospital Medical Center Regulation of CCR3 expression
US8030003B2 (en) * 2004-12-07 2011-10-04 Children's Hospital Medical Center Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3
US8008092B2 (en) * 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
WO2010069979A1 (en) * 2008-12-16 2010-06-24 Nycomed Gmbh Pyran derivatives as ccr3 modulators
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
US8278302B2 (en) * 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
US8778616B2 (en) * 2009-05-26 2014-07-15 University Of Kentucky Research Foundation Method of using CCR3 binding agents to detect choroidal neovascularization
UA109290C2 (uk) * 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US20130261153A1 (en) * 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) * 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
WO2020115836A1 (ja) * 2018-12-05 2020-06-11 東浜工業株式会社 ブロワー装置

Also Published As

Publication number Publication date
LT2833884T (lt) 2020-09-10
CN110384699A (zh) 2019-10-29
PT2833884T (pt) 2020-08-26
NZ628882A (en) 2016-05-27
ES2987267T3 (es) 2024-11-14
BR112014023795A8 (pt) 2017-10-10
EP2833884A1 (en) 2015-02-11
HUE051648T2 (hu) 2021-03-29
WO2013149986A1 (en) 2013-10-10
EA201401083A1 (ru) 2015-03-31
ES2811554T3 (es) 2021-03-12
PL2833884T3 (pl) 2020-11-02
SI2833884T1 (sl) 2020-10-30
KR20140144200A (ko) 2014-12-18
KR20250133980A (ko) 2025-09-09
SMT202000499T1 (it) 2020-11-10
AU2013245027A1 (en) 2014-09-11
KR20200044988A (ko) 2020-04-29
BR112014023795B1 (pt) 2021-09-08
CN104220073A (zh) 2014-12-17
KR20220132012A (ko) 2022-09-29
IL234262A (en) 2017-10-31
US20200375971A1 (en) 2020-12-03
IN2014DN06989A (OSRAM) 2015-04-10
ZA201406082B (en) 2019-01-30
AU2013245027B2 (en) 2017-10-12
DK2833884T3 (da) 2020-08-10
CL2014002523A1 (es) 2015-01-23
US20170319567A1 (en) 2017-11-09
JP2015512432A (ja) 2015-04-27
EP3763369B1 (en) 2024-02-28
US20150099783A1 (en) 2015-04-09
US20160081998A1 (en) 2016-03-24
KR20210063481A (ko) 2021-06-01
RS60665B1 (sr) 2020-09-30
JP2018080183A (ja) 2018-05-24
EP2833884B1 (en) 2020-05-20
CA2869269A1 (en) 2013-10-10
US20130261153A1 (en) 2013-10-03
BR112014023795A2 (OSRAM) 2017-06-20
HRP20201165T1 (hr) 2020-12-11
EA032263B1 (ru) 2019-05-31
PH12014502239A1 (en) 2014-12-15
CA2869269C (en) 2020-06-30
CY1123222T1 (el) 2021-10-29
EP4389217A3 (en) 2024-08-28
EP4389217A2 (en) 2024-06-26
EP3763369A1 (en) 2021-01-13

Similar Documents

Publication Publication Date Title
MX2014011786A (es) Uso de inhibidores de ccr3.
BR112017010354A2 (pt) compostos de triazolopirimidina e usos dos mesmos
CU24083B1 (es) Derivados de oxazina útiles como inhibidores de bace para el tratamiento de trastornos neurológicos
CU20130101A7 (es) Derivados de 1,4-oxazin-3-il-piridin-2-il-acetamida, activos como inhibidores bace-1 o bace-2
ECSP13012494A (es) Inhibidores de oxadiazol de la producción de leucotrieno.
CU24265B1 (es) Compuestos derivados de benzamida para inhibir la actividad de abl1, abl2 y bcr-abl1, útiles en el tratamiento del cáncer
PE20150666A1 (es) Inhibidores de serina/treonina cinasa
UY37311A (es) Derivados de 5,7-dihidro-pirrolo-piridina
CU24187B1 (es) Derivados sustituidos de imidazopiridazinas útiles para el tratamiento o profilaxis de trastornos hiperproliferativos y la angiogénesis
PE20141972A1 (es) Inhibidores de la beta-secretasa
MX2019012815A (es) Proceso para la preparacion de compuestos de 2,3-dihidrotiazolo[3, 2-a]pirimidin-4-io opticamente activo.
CL2019000512A1 (es) Nuevos compuestos sulfonimidoilpurinona 7-sustituidos y derivados para el tratamiento y la profilaxis de la infección vírica.
ECSP20035588A (es) Derivado de amino-metil piperidina como inhibidor de quinasa
CU20110142A6 (es) Procedimiento para tratar enfermedades inflamatorias o alérgicas
ECSP19030134A (es) Compuesto de piridina
BR112014008759A8 (pt) Tratamento de doença ocular
ECSP14013274A (es) Heterociclaminas como inhibidores de pi3k
CU24097B1 (es) Compuestos piridiloxi-indoles sustituidos como inhibidores del vegf-r2 útiles para el tratamiento de enfermedades proliferativas
BR112015021701A2 (pt) novos compostos inibidores da fosfoestearase tipo 10a
PE20151001A1 (es) Alcoxipirazoles como activadores de guanilato ciclasa soluble
MX2019003026A (es) Compuestos de heteroarilcarboxamida como inhibidores de ripk2.
AR092253A1 (es) Inhibidores de serina/treonina cinasa
BR112014009717A8 (pt) derivados de 2-(fenil ou pirid-3-il)aminopirimidina como moduladores de cinase lrrk2 para o tratamento de doença de parkinson.
ECSP11010885A (es) Heteroarilos sustituidos
UY34955A (es) 4-metil-2,3,5,9,9b-pentaaza-ciclopenta[a]naftalenos