HUE051648T2 - CCR3-gátlók használata - Google Patents

CCR3-gátlók használata

Info

Publication number
HUE051648T2
HUE051648T2 HUE13713199A HUE13713199A HUE051648T2 HU E051648 T2 HUE051648 T2 HU E051648T2 HU E13713199 A HUE13713199 A HU E13713199A HU E13713199 A HUE13713199 A HU E13713199A HU E051648 T2 HUE051648 T2 HU E051648T2
Authority
HU
Hungary
Prior art keywords
ccr3 inhibitors
ccr3
inhibitors
Prior art date
Application number
HUE13713199A
Other languages
English (en)
Hungarian (hu)
Inventor
Michael Chadham Nivens
Thierry Bouyssou
Rolf Goeggel
Peter Seither
Original Assignee
Alkahest Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48040249&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE051648(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alkahest Inc filed Critical Alkahest Inc
Publication of HUE051648T2 publication Critical patent/HUE051648T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Structure Of Transmissions (AREA)
HUE13713199A 2012-04-03 2013-04-02 CCR3-gátlók használata HUE051648T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12162937 2012-04-03

Publications (1)

Publication Number Publication Date
HUE051648T2 true HUE051648T2 (hu) 2021-03-29

Family

ID=48040249

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE13713199A HUE051648T2 (hu) 2012-04-03 2013-04-02 CCR3-gátlók használata

Country Status (28)

Country Link
US (5) US20130261153A1 (OSRAM)
EP (3) EP3763369B1 (OSRAM)
JP (2) JP2015512432A (OSRAM)
KR (5) KR20200044988A (OSRAM)
CN (2) CN104220073A (OSRAM)
AU (1) AU2013245027B2 (OSRAM)
BR (1) BR112014023795B1 (OSRAM)
CA (1) CA2869269C (OSRAM)
CL (1) CL2014002523A1 (OSRAM)
CY (1) CY1123222T1 (OSRAM)
DK (1) DK2833884T3 (OSRAM)
EA (1) EA032263B1 (OSRAM)
ES (2) ES2811554T3 (OSRAM)
HR (1) HRP20201165T1 (OSRAM)
HU (1) HUE051648T2 (OSRAM)
IL (1) IL234262A (OSRAM)
IN (1) IN2014DN06989A (OSRAM)
LT (1) LT2833884T (OSRAM)
MX (1) MX2014011786A (OSRAM)
NZ (1) NZ628882A (OSRAM)
PH (1) PH12014502239A1 (OSRAM)
PL (1) PL2833884T3 (OSRAM)
PT (1) PT2833884T (OSRAM)
RS (1) RS60665B1 (OSRAM)
SI (1) SI2833884T1 (OSRAM)
SM (1) SMT202000499T1 (OSRAM)
WO (1) WO2013149986A1 (OSRAM)
ZA (1) ZA201406082B (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US8680280B2 (en) 2012-04-02 2014-03-25 Boehringer Ingelheim International Gmbh Process for the manufacturing of CRR inhibitors
US20130261153A1 (en) * 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
CN109310486B (zh) 2016-11-24 2021-07-02 雾岛精工株式会社 齿列矫正器和齿列矫正器的安装方法
EP3606521B1 (en) * 2017-04-05 2023-04-19 Alkahest, Inc. Compounds and pharmaceutical compositions for use in treating retina-associated disease using ccr3-inhibitors
MX394341B (es) 2017-04-05 2025-03-24 Alkahest Inc Metodos y composiciones para tratar deterioros asociados con el envejecimiento usando inhibidores de ccr3
CA3076017A1 (en) * 2017-10-13 2019-04-18 Alkahest, Inc. Methods and compositions for treating pruritus, xerosis, and associated disease using ccr3-inhibitors
SG11202010115RA (en) 2018-05-15 2020-11-27 Alkahest Inc Treatment of aging-associated disease with modulators of leukotriene a4 hydrolase
EA202190463A1 (ru) * 2018-09-26 2021-06-29 Алкахест, Инк. Способы и композиции для лечения ассоциированных со старением нарушений с применением ccr3-ингибиторов
WO2021252647A1 (en) * 2020-06-11 2021-12-16 Alkahest Inc. Methods of improving retina-associated disease outcome using ccr3-inhibitors
AU2022376563A1 (en) 2021-11-01 2023-12-07 Alkahest, Inc. Benzodioxane modulators of leukotriene a4 hydrolase (lta4h) for prevention and treatment of aging-associated diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6339087B1 (en) * 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
ATE414151T1 (de) * 2000-03-03 2008-11-15 Cambridge Antibody Tech Antikörper gegen eotaxin und deren verwendung
US20020151064A1 (en) * 2001-02-07 2002-10-17 Children's Hospital Medical Center Regulation of CCR3 expression
US8030003B2 (en) * 2004-12-07 2011-10-04 Children's Hospital Medical Center Diagnosis of eosinophilic esophagitis based on presence of an elevated level of eotaxin-3
US8008092B2 (en) * 2007-10-09 2011-08-30 University Of Kentucky Research Foundation CCR3 inhibition for ocular angiogenesis and macular degeneration
WO2010069979A1 (en) * 2008-12-16 2010-06-24 Nycomed Gmbh Pyran derivatives as ccr3 modulators
EP2236520A1 (en) * 2009-03-31 2010-10-06 Leukocare Ag Stabilizing composition for immobilized biomolecules
US8278302B2 (en) * 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
US8778616B2 (en) * 2009-05-26 2014-07-15 University Of Kentucky Research Foundation Method of using CCR3 binding agents to detect choroidal neovascularization
UA109290C2 (uk) * 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US20130261153A1 (en) * 2012-04-03 2013-10-03 Boehringer Ingelheim International Gmbh Use of ccr3-inhibitors
US10213421B2 (en) * 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
WO2020115836A1 (ja) * 2018-12-05 2020-06-11 東浜工業株式会社 ブロワー装置

Also Published As

Publication number Publication date
LT2833884T (lt) 2020-09-10
CN110384699A (zh) 2019-10-29
PT2833884T (pt) 2020-08-26
NZ628882A (en) 2016-05-27
ES2987267T3 (es) 2024-11-14
BR112014023795A8 (pt) 2017-10-10
EP2833884A1 (en) 2015-02-11
WO2013149986A1 (en) 2013-10-10
EA201401083A1 (ru) 2015-03-31
ES2811554T3 (es) 2021-03-12
PL2833884T3 (pl) 2020-11-02
SI2833884T1 (sl) 2020-10-30
KR20140144200A (ko) 2014-12-18
KR20250133980A (ko) 2025-09-09
SMT202000499T1 (it) 2020-11-10
AU2013245027A1 (en) 2014-09-11
KR20200044988A (ko) 2020-04-29
BR112014023795B1 (pt) 2021-09-08
CN104220073A (zh) 2014-12-17
KR20220132012A (ko) 2022-09-29
IL234262A (en) 2017-10-31
US20200375971A1 (en) 2020-12-03
IN2014DN06989A (OSRAM) 2015-04-10
ZA201406082B (en) 2019-01-30
AU2013245027B2 (en) 2017-10-12
DK2833884T3 (da) 2020-08-10
CL2014002523A1 (es) 2015-01-23
US20170319567A1 (en) 2017-11-09
JP2015512432A (ja) 2015-04-27
EP3763369B1 (en) 2024-02-28
US20150099783A1 (en) 2015-04-09
US20160081998A1 (en) 2016-03-24
KR20210063481A (ko) 2021-06-01
RS60665B1 (sr) 2020-09-30
MX2014011786A (es) 2014-12-05
JP2018080183A (ja) 2018-05-24
EP2833884B1 (en) 2020-05-20
CA2869269A1 (en) 2013-10-10
US20130261153A1 (en) 2013-10-03
BR112014023795A2 (OSRAM) 2017-06-20
HRP20201165T1 (hr) 2020-12-11
EA032263B1 (ru) 2019-05-31
PH12014502239A1 (en) 2014-12-15
CA2869269C (en) 2020-06-30
CY1123222T1 (el) 2021-10-29
EP4389217A3 (en) 2024-08-28
EP4389217A2 (en) 2024-06-26
EP3763369A1 (en) 2021-01-13

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