MX2014010712A - Biocontrol. - Google Patents
Biocontrol.Info
- Publication number
- MX2014010712A MX2014010712A MX2014010712A MX2014010712A MX2014010712A MX 2014010712 A MX2014010712 A MX 2014010712A MX 2014010712 A MX2014010712 A MX 2014010712A MX 2014010712 A MX2014010712 A MX 2014010712A MX 2014010712 A MX2014010712 A MX 2014010712A
- Authority
- MX
- Mexico
- Prior art keywords
- transcription factor
- expression
- promoter
- effector gene
- regulatory element
- Prior art date
Links
- 230000000443 biocontrol Effects 0.000 title abstract 2
- 230000014509 gene expression Effects 0.000 abstract 7
- 108091023040 Transcription factor Proteins 0.000 abstract 6
- 102000040945 Transcription factor Human genes 0.000 abstract 6
- 239000012636 effector Substances 0.000 abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 230000001105 regulatory effect Effects 0.000 abstract 3
- 238000011144 upstream manufacturing Methods 0.000 abstract 3
- 241000238421 Arthropoda Species 0.000 abstract 2
- 108091026890 Coding region Proteins 0.000 abstract 2
- 210000004602 germ cell Anatomy 0.000 abstract 2
- 108020003589 5' Untranslated Regions Proteins 0.000 abstract 1
- 230000021121 meiosis Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
- A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
- A01M99/00—Subject matter not provided for in other groups of this subclass
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
- C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/002—Vectors comprising a special translation-regulating system controllable or inducible
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Pest Control & Pesticides (AREA)
- Insects & Arthropods (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Se proporciona un sistema de expresión genética de la línea germinal masculina de artrópodos adecuado para la expresión condicional de un gen efector en una línea germinal masculina de artrópodos. El sistema comprende una primera unidad de expresión que comprende un gen efector y un promotor para el mismo operativamente enlazado al mismo; y una segunda unidad de expresión. La segunda unidad comprende una secuencia de codificación para un factor de transcripción y un elemento regulador corriente arriba operativamente enlazado al mismo, siendo el factor de transcripción capaz de actuar sobre el promotor en la primera unidad de expresión para impulsar la expresión del gen efector. El elemento regulador corriente arriba incluye un promotor para el factor de transcripción; y una UTR 5' adyacente a un sitio de inicio para la secuencia de codificación del factor de transcripción. El elemento regulador corriente arriba que impulsa suficiente expresión del factor de transcripción, de tal manera que la proteína del factor de transcripción a su vz impulsa la transcripción del gen efector antes de la meiosis. También se proporcionan los usos del sistema, por ejemplo, en métodos de control biológico y control de calidad.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1203850.1A GB2500113A (en) | 2012-03-05 | 2012-03-05 | Arthropod male germline gene expression system |
| PCT/EP2013/054417 WO2013131920A1 (en) | 2012-03-05 | 2013-03-05 | Biocontrol |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014010712A true MX2014010712A (es) | 2015-03-10 |
| MX359468B MX359468B (es) | 2018-09-28 |
Family
ID=46003145
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014010712A MX359468B (es) | 2012-03-05 | 2013-03-05 | Biocontrol. |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US9487801B2 (es) |
| EP (2) | EP2823047B1 (es) |
| JP (1) | JP6363023B2 (es) |
| CN (2) | CN108018309A (es) |
| AR (1) | AR091314A1 (es) |
| AU (2) | AU2013229578B2 (es) |
| BR (1) | BR112014021922B1 (es) |
| CA (1) | CA2866411A1 (es) |
| CL (1) | CL2014002369A1 (es) |
| CO (1) | CO7160024A2 (es) |
| CR (1) | CR20140439A (es) |
| CY (1) | CY1120531T1 (es) |
| ES (1) | ES2683039T3 (es) |
| GB (1) | GB2500113A (es) |
| GT (1) | GT201400188A (es) |
| MA (1) | MA37380B1 (es) |
| MX (1) | MX359468B (es) |
| MY (1) | MY169450A (es) |
| PE (1) | PE20142278A1 (es) |
| PH (1) | PH12014501993B1 (es) |
| SG (2) | SG11201405481SA (es) |
| WO (1) | WO2013131920A1 (es) |
| ZA (1) | ZA201406925B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
| GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
| GB201303932D0 (en) | 2013-03-05 | 2013-04-17 | Oxitec Ltd | Muscle actin promoter |
| CN106133141B (zh) * | 2014-01-08 | 2021-08-20 | 哈佛学院董事及会员团体 | Rna引导的基因驱动 |
| GB2526867A (en) | 2014-06-05 | 2015-12-09 | Oxitec Ltd | Gene expression system |
| WO2018029534A1 (en) | 2016-08-12 | 2018-02-15 | Oxitec Ltd. | A self-limiting, sex-specific gene and methods of using |
| GB201810253D0 (en) * | 2018-06-22 | 2018-08-08 | Imperial Innovations Ltd | Gene drive |
| GB201810256D0 (en) * | 2018-06-22 | 2018-08-08 | Imperial Innovations Ltd | Polynucleotide |
| MA52650A1 (fr) * | 2018-08-14 | 2021-12-31 | Oxitec Ltd | Arthropodes mâles stériles à sélection automatique |
| CN109105341A (zh) * | 2018-09-04 | 2019-01-01 | 安徽师范大学 | 一种用于防治斑翅果蝇的辐照不育方法 |
| GB2579224A (en) * | 2018-11-26 | 2020-06-17 | Zyzzle Ltd | Apparatus for producing an improved animal population |
| EP3660053A1 (en) * | 2018-11-27 | 2020-06-03 | Fraunhofer Gesellschaft zur Förderung der Angewand | Multiprotein expression systems for pest control |
| CA3128360A1 (en) * | 2019-03-05 | 2020-09-10 | Yuval CINNAMON | Genome-edited birds |
| CN114395018A (zh) * | 2021-12-31 | 2022-04-26 | 天津大学 | CifA和CifB突变蛋白用于调控胞质不相容性的用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5180873A (en) | 1985-04-16 | 1993-01-19 | Dna Plant Technology Corporation | Transformation of plants to introduce closely linked markers |
| GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
| US5643776A (en) | 1988-11-01 | 1997-07-01 | The Regents Of The University Of California | Insect diagnostic and control compositions |
| US5254801A (en) | 1990-12-03 | 1993-10-19 | Monsanto Company | Heterologous dominant conditional lethal gene which is a phosphonate monoester hydrolase and use thereof in plants |
| GB9216151D0 (en) | 1992-07-29 | 1992-09-09 | Ici Plc | Containment of plant germplasm |
| US6225121B1 (en) | 1992-09-14 | 2001-05-01 | Institute Of Molecular Biology And Biotechnology/Forth | Eukaryotic transposable element |
| GB9313975D0 (en) | 1993-07-06 | 1993-08-18 | Sandoz Ltd | Improvements in or relating to organic compounds |
| EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
| US5633447A (en) | 1994-08-25 | 1997-05-27 | Mycogen Plant Science, Inc. | Plant tissue comprising a subgenomic promoter |
| US5753434A (en) | 1995-02-10 | 1998-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for altering sexual behavior |
| US5851796A (en) | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
| FR2737731B1 (fr) | 1995-08-07 | 1997-10-10 | Pasteur Institut | Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote |
| AUPN816196A0 (en) | 1996-02-19 | 1996-03-14 | Forbio Research Pty Ltd | Regulation of eukaryotic gene expression |
| US5773697A (en) | 1996-04-23 | 1998-06-30 | Pioneer Hi-Bred International, Inc. | Genetic constructs and methods for producing fruits with very little or diminished seed |
| WO1998008960A1 (en) | 1996-08-26 | 1998-03-05 | Genencor International, Inc. | IDENTIFICATION OF AND CLONING A MOBILE TRANSPOSON FROM $i(ASPERGILLUS) |
| WO1998014578A1 (en) * | 1996-10-01 | 1998-04-09 | University Of Georgia Research Foundation, Inc. | Biological insect control agents expressing insect-specific mite toxin genes, methods and compositions |
| US7135608B1 (en) | 1997-08-28 | 2006-11-14 | The Salk Institute For Biological Studies | Site-specific recombination in eukaryotes and constructs useful therefor |
| US6338040B1 (en) | 1999-02-12 | 2002-01-08 | Agren, Inc. | Method for delaying the development in pest species of resistance to control techniques, using insurance to encourage correct uses of refuges |
| EP1187938B1 (en) | 1999-06-01 | 2011-11-09 | The University of Utah Research Foundation | Method of regulated expression of transgenes in the germline of caenorhabditis elegans |
| GB2355459B (en) | 1999-11-29 | 2001-09-26 | Isis Innovation | A dominant conditional lethal genetic system |
| EP1257657A2 (en) * | 2000-02-11 | 2002-11-20 | QUEEN MARY & WESTFIELD COLLEGE | Autoregulatory expression vector for gene therapy |
| US20030150007A1 (en) | 2000-03-21 | 2003-08-07 | Charalambos Savakis | Method of generating transgenic organisms using transposons |
| AU2001265187A1 (en) | 2000-05-30 | 2001-12-11 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
| US6962810B2 (en) | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
| AU2002225888A1 (en) | 2000-12-05 | 2002-06-18 | Wisconsin Alumni Research Foundation. | Double transposition methods for manipulating nucleic acids |
| ITRM20010120A1 (it) | 2001-03-08 | 2002-09-08 | Univ Napoli Federico Ii | Gene cctra come strumento per produrre progenie di soli maschi nella mosca mediterranea ceratitis capitata. |
| FR2825579B1 (fr) | 2001-06-11 | 2004-07-23 | Rhobio | Methode d'obtention de plante monocotyledone contenant un gene d'interet sans sequence auxiliaire etrangere |
| DE10251918A1 (de) | 2002-11-08 | 2004-05-19 | Horn, Carsten, Dipl.-Biochem. Dr. | Systeme zur Erzeugung stabiler genomischer Transgen-Insertionen |
| GB2402675B (en) | 2003-05-12 | 2008-02-20 | Oxitec Ltd | Resistance dilution |
| ATE406450T1 (de) | 2003-06-10 | 2008-09-15 | Ca Nat Research Council | Ein coumermycin/novobiocin-reguliertes genexpressionsystem |
| GB2403475B (en) | 2003-07-01 | 2008-02-06 | Oxitec Ltd | Stable integrands |
| GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
| BRPI0508862A (pt) | 2004-03-15 | 2007-09-04 | Biogen Idec Inc | métodos e construtos para expressar multìmeros de polipeptìdios em células eucarióticas utilizando junção alternativa |
| US7563601B1 (en) | 2005-06-01 | 2009-07-21 | City Of Hope | Artificial riboswitch for controlling pre-mRNA splicing |
| EP1984512B1 (en) | 2006-02-10 | 2016-12-07 | Oxitec Limited | Gene expression system using alternative splicing in insects |
| GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
| JP2008067678A (ja) * | 2006-09-15 | 2008-03-27 | Kyushu Institute Of Technology | 昆虫の減数分裂期における染色体標的組換え誘導方法 |
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| WO2009016627A1 (en) * | 2007-07-30 | 2009-02-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Sex-peptides resistant to proteolytic degradation and their use in biological control of insects |
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| EP3456190B1 (en) | 2008-06-27 | 2021-11-24 | Merus N.V. | Antibody producing transgenic murine animal |
| CN102939383B (zh) * | 2009-12-30 | 2015-04-29 | 先锋国际良种公司 | 用于靶向多核苷酸修饰的方法和组合物 |
-
2012
- 2012-03-05 GB GB1203850.1A patent/GB2500113A/en not_active Withdrawn
-
2013
- 2013-03-05 CN CN201710958978.2A patent/CN108018309A/zh active Pending
- 2013-03-05 EP EP13711848.5A patent/EP2823047B1/en active Active
- 2013-03-05 JP JP2014560338A patent/JP6363023B2/ja not_active Expired - Fee Related
- 2013-03-05 ES ES13711848T patent/ES2683039T3/es active Active
- 2013-03-05 CA CA2866411A patent/CA2866411A1/en not_active Abandoned
- 2013-03-05 SG SG11201405481SA patent/SG11201405481SA/en unknown
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2014
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2016
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2017
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