CO7160024A2 - Biocontrol - Google Patents
BiocontrolInfo
- Publication number
- CO7160024A2 CO7160024A2 CO14218631A CO14218631A CO7160024A2 CO 7160024 A2 CO7160024 A2 CO 7160024A2 CO 14218631 A CO14218631 A CO 14218631A CO 14218631 A CO14218631 A CO 14218631A CO 7160024 A2 CO7160024 A2 CO 7160024A2
- Authority
- CO
- Colombia
- Prior art keywords
- expression
- unit
- effector gene
- arthropod
- promoter
- Prior art date
Links
- 230000000443 biocontrol Effects 0.000 title 1
- 239000012636 effector Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 241000238421 Arthropoda Species 0.000 abstract 2
- 108091023040 Transcription factor Proteins 0.000 abstract 2
- 102000040945 Transcription factor Human genes 0.000 abstract 2
- 210000004602 germ cell Anatomy 0.000 abstract 2
- 108091026890 Coding region Proteins 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
- A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
- A01M99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/203—Animal model comprising inducible/conditional expression system, e.g. hormones, tet
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/20—Animal model comprising regulated expression system
- A01K2217/206—Animal model comprising tissue-specific expression system, e.g. tissue specific expression of transgene, of Cre recombinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/70—Invertebrates
- A01K2227/706—Insects, e.g. Drosophila melanogaster, medfly
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/02—Animal zootechnically ameliorated
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0393—Animal model comprising a reporter system for screening tests
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
- C07K2319/81—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor containing a Zn-finger domain for DNA binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/90—Vectors containing a transposable element
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/002—Vectors comprising a special translation-regulating system controllable or inducible
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Insects & Arthropods (AREA)
- Pest Control & Pesticides (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se proporciona un sistema de expresión genética de la línea germinal masculina de artrópodos adecuado para la expresión condicional de un gen efector en una línea germinal masculina de artrópodos. el sistema comprende un gen efector y un promotor para el mismo operativamente enlazado al mismo; y una segunda unidad de expresión. La segunda unidad comprende una secuencia de codificación para un factor de transcripción y un elemento regulador corriente arriba operativamente enlazado al mismo, siendo el factor de transcripción capaz de actuar sobre el promotor en la primera unidad de expresión para impulsar la expresión del gen efector.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1203850.1A GB2500113A (en) | 2012-03-05 | 2012-03-05 | Arthropod male germline gene expression system |
Publications (1)
Publication Number | Publication Date |
---|---|
CO7160024A2 true CO7160024A2 (es) | 2015-01-15 |
Family
ID=46003145
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO14218631A CO7160024A2 (es) | 2012-03-05 | 2014-10-02 | Biocontrol |
Country Status (23)
Country | Link |
---|---|
US (2) | US9487801B2 (es) |
EP (2) | EP3395949A1 (es) |
JP (1) | JP6363023B2 (es) |
CN (2) | CN104271747B (es) |
AR (2) | AR091314A1 (es) |
AU (2) | AU2013229578B2 (es) |
BR (1) | BR112014021922B1 (es) |
CA (1) | CA2866411A1 (es) |
CL (1) | CL2014002369A1 (es) |
CO (1) | CO7160024A2 (es) |
CR (1) | CR20140439A (es) |
CY (1) | CY1120531T1 (es) |
ES (1) | ES2683039T3 (es) |
GB (1) | GB2500113A (es) |
GT (1) | GT201400188A (es) |
MA (1) | MA37380B1 (es) |
MX (1) | MX359468B (es) |
MY (1) | MY169450A (es) |
PE (1) | PE20142278A1 (es) |
PH (1) | PH12014501993B1 (es) |
SG (2) | SG11201405481SA (es) |
WO (1) | WO2013131920A1 (es) |
ZA (1) | ZA201406925B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2404382B (en) | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
GB201303932D0 (en) | 2013-03-05 | 2013-04-17 | Oxitec Ltd | Muscle actin promoter |
SG11201605550QA (en) * | 2014-01-08 | 2016-08-30 | Harvard College | Rna-guided gene drives |
GB2526867A (en) | 2014-06-05 | 2015-12-09 | Oxitec Ltd | Gene expression system |
US11827876B2 (en) | 2016-08-12 | 2023-11-28 | Oxitec Ltd. | Self-limiting, sex-specific gene and methods of using |
GB201810256D0 (en) * | 2018-06-22 | 2018-08-08 | Imperial Innovations Ltd | Polynucleotide |
GB201810253D0 (en) * | 2018-06-22 | 2018-08-08 | Imperial Innovations Ltd | Gene drive |
BR112021002776A8 (pt) * | 2018-08-14 | 2021-05-18 | Oxitec Ltd | artrópodes macho estéril de auto-seleção |
CN109105341A (zh) * | 2018-09-04 | 2019-01-01 | 安徽师范大学 | 一种用于防治斑翅果蝇的辐照不育方法 |
GB2579224A (en) * | 2018-11-26 | 2020-06-17 | Zyzzle Ltd | Apparatus for producing an improved animal population |
EP3660053A1 (en) * | 2018-11-27 | 2020-06-03 | Fraunhofer Gesellschaft zur Förderung der Angewand | Multiprotein expression systems for pest control |
MX2021010611A (es) * | 2019-03-05 | 2021-11-12 | The State Of Israel Ministry Of Agriculture & Rural Development Agricultural Res Organization Aro Vo | Aves con genoma editado. |
CN114395018A (zh) * | 2021-12-31 | 2022-04-26 | 天津大学 | CifA和CifB突变蛋白用于调控胞质不相容性的用途 |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180873A (en) | 1985-04-16 | 1993-01-19 | Dna Plant Technology Corporation | Transformation of plants to introduce closely linked markers |
GB8901677D0 (en) | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
US5643776A (en) | 1988-11-01 | 1997-07-01 | The Regents Of The University Of California | Insect diagnostic and control compositions |
US5254801A (en) | 1990-12-03 | 1993-10-19 | Monsanto Company | Heterologous dominant conditional lethal gene which is a phosphonate monoester hydrolase and use thereof in plants |
GB9216151D0 (en) | 1992-07-29 | 1992-09-09 | Ici Plc | Containment of plant germplasm |
US6225121B1 (en) | 1992-09-14 | 2001-05-01 | Institute Of Molecular Biology And Biotechnology/Forth | Eukaryotic transposable element |
GB9313975D0 (en) | 1993-07-06 | 1993-08-18 | Sandoz Ltd | Improvements in or relating to organic compounds |
EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
US5670353A (en) | 1994-08-25 | 1997-09-23 | Mycogen Plant Science, Inc. | Subgenomic promoter |
US5753434A (en) | 1995-02-10 | 1998-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for altering sexual behavior |
US5851796A (en) | 1995-06-07 | 1998-12-22 | Yale University | Autoregulatory tetracycline-regulated system for inducible gene expression in eucaryotes |
FR2737731B1 (fr) | 1995-08-07 | 1997-10-10 | Pasteur Institut | Sequence de retroelements naturels ou synthetiques ayant pour fonction de permettre l'insertion de sequences nucleotidiques dans une cellule eucaryote |
AUPN816196A0 (en) | 1996-02-19 | 1996-03-14 | Forbio Research Pty Ltd | Regulation of eukaryotic gene expression |
US5773697A (en) | 1996-04-23 | 1998-06-30 | Pioneer Hi-Bred International, Inc. | Genetic constructs and methods for producing fruits with very little or diminished seed |
EP0920521A1 (en) | 1996-08-26 | 1999-06-09 | Genencor International, Inc. | IDENTIFICATION OF AND CLONING A MOBILE TRANSPOSON FROM $i(ASPERGILLUS) |
NZ334604A (en) * | 1996-10-01 | 1999-11-29 | American Cyanamid Co | A DNA molecule containing a baculovirus promoter operable linked to a coding sequnce for an insect-specific toxin; biological insect control agents comprising the altered baculovirus |
US7135608B1 (en) | 1997-08-28 | 2006-11-14 | The Salk Institute For Biological Studies | Site-specific recombination in eukaryotes and constructs useful therefor |
US6338040B1 (en) | 1999-02-12 | 2002-01-08 | Agren, Inc. | Method for delaying the development in pest species of resistance to control techniques, using insurance to encourage correct uses of refuges |
WO2000073510A1 (en) | 1999-06-01 | 2000-12-07 | University Of Utah Research Foundation | iETHOD OF TRANSPOSON-MEDIATED MUTAGENESIS IN THE NEMATODE CAENORHABDITIS ELEGANS |
GB2355459B (en) * | 1999-11-29 | 2001-09-26 | Isis Innovation | A dominant conditional lethal genetic system |
WO2001059088A2 (en) * | 2000-02-11 | 2001-08-16 | Queen Mary & Westfield College | Vector |
US20030150007A1 (en) | 2000-03-21 | 2003-08-07 | Charalambos Savakis | Method of generating transgenic organisms using transposons |
AU2001265187A1 (en) | 2000-05-30 | 2001-12-11 | Baylor College Of Medicine | Chimeric viral vectors for gene therapy |
US6962810B2 (en) | 2000-10-31 | 2005-11-08 | University Of Notre Dame Du Lac | Methods and compositions for transposition using minimal segments of the eukaryotic transformation vector piggyBac |
EP1339863A2 (en) | 2000-12-05 | 2003-09-03 | Wisconsin Alumni Research Foundation | Double transposition methods for manipulating nucleic acids |
ITRM20010120A1 (it) | 2001-03-08 | 2002-09-08 | Univ Napoli Federico Ii | Gene cctra come strumento per produrre progenie di soli maschi nella mosca mediterranea ceratitis capitata. |
FR2825579B1 (fr) | 2001-06-11 | 2004-07-23 | Rhobio | Methode d'obtention de plante monocotyledone contenant un gene d'interet sans sequence auxiliaire etrangere |
DE10251918A1 (de) | 2002-11-08 | 2004-05-19 | Horn, Carsten, Dipl.-Biochem. Dr. | Systeme zur Erzeugung stabiler genomischer Transgen-Insertionen |
GB2402675B (en) | 2003-05-12 | 2008-02-20 | Oxitec Ltd | Resistance dilution |
WO2004108933A1 (en) | 2003-06-10 | 2004-12-16 | National Research Council Of Canada | A coumermycin/novobiocin-regulated gene expression system |
GB2403475B (en) | 2003-07-01 | 2008-02-06 | Oxitec Ltd | Stable integrands |
GB2404382B (en) * | 2003-07-28 | 2008-01-30 | Oxitec Ltd | Pest control |
BRPI0508862A (pt) | 2004-03-15 | 2007-09-04 | Biogen Idec Inc | métodos e construtos para expressar multìmeros de polipeptìdios em células eucarióticas utilizando junção alternativa |
US7563601B1 (en) | 2005-06-01 | 2009-07-21 | City Of Hope | Artificial riboswitch for controlling pre-mRNA splicing |
GB2443186A (en) | 2006-10-25 | 2008-04-30 | Oxitec Ltd | Expression system for mediating alternative splicing |
CN101421408A (zh) | 2006-02-10 | 2009-04-29 | 奥西泰克有限公司 | 昆虫中利用可变剪接的基因表达系统 |
JP2008067678A (ja) * | 2006-09-15 | 2008-03-27 | Kyushu Institute Of Technology | 昆虫の減数分裂期における染色体標的組換え誘導方法 |
WO2008134068A2 (en) * | 2007-04-26 | 2008-11-06 | Hawaii Biotech, Inc. | Synthetic expression vectors for insect cells |
US8677934B2 (en) * | 2007-07-30 | 2014-03-25 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Sex-peptides resistant to proteolytic degradation and their use in biological control of insects |
WO2009115569A1 (en) * | 2008-03-20 | 2009-09-24 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts | Developmental stage-specific lethality system for insect population control |
CA2729095C (en) | 2008-06-27 | 2018-12-04 | Merus B.V. | Method for producing a transgenic murine mammal |
US8704041B2 (en) * | 2009-12-30 | 2014-04-22 | Pioneer Hi Bred International Inc | Methods and compositions for targeted polynucleotide modification |
-
2012
- 2012-03-05 GB GB1203850.1A patent/GB2500113A/en not_active Withdrawn
-
2013
- 2013-03-05 MY MYPI2014002574A patent/MY169450A/en unknown
- 2013-03-05 BR BR112014021922-2A patent/BR112014021922B1/pt active IP Right Grant
- 2013-03-05 PE PE2014001359A patent/PE20142278A1/es active IP Right Grant
- 2013-03-05 EP EP18163791.9A patent/EP3395949A1/en not_active Withdrawn
- 2013-03-05 JP JP2014560338A patent/JP6363023B2/ja not_active Expired - Fee Related
- 2013-03-05 CA CA2866411A patent/CA2866411A1/en not_active Abandoned
- 2013-03-05 US US14/383,515 patent/US9487801B2/en active Active
- 2013-03-05 SG SG11201405481SA patent/SG11201405481SA/en unknown
- 2013-03-05 EP EP13711848.5A patent/EP2823047B1/en active Active
- 2013-03-05 AU AU2013229578A patent/AU2013229578B2/en active Active
- 2013-03-05 ES ES13711848T patent/ES2683039T3/es active Active
- 2013-03-05 WO PCT/EP2013/054417 patent/WO2013131920A1/en active Application Filing
- 2013-03-05 CN CN201380023783.9A patent/CN104271747B/zh active Active
- 2013-03-05 SG SG10201702181PA patent/SG10201702181PA/en unknown
- 2013-03-05 MX MX2014010712A patent/MX359468B/es active IP Right Grant
- 2013-03-05 AR ARP130100723 patent/AR091314A1/es active IP Right Grant
- 2013-03-05 CN CN201710958978.2A patent/CN108018309A/zh active Pending
-
2014
- 2014-09-05 GT GT201400188A patent/GT201400188A/es unknown
- 2014-09-05 CL CL2014002369A patent/CL2014002369A1/es unknown
- 2014-09-05 PH PH12014501993A patent/PH12014501993B1/en unknown
- 2014-09-22 ZA ZA2014/06925A patent/ZA201406925B/en unknown
- 2014-09-23 CR CR20140439A patent/CR20140439A/es unknown
- 2014-09-26 MA MA37380A patent/MA37380B1/fr unknown
- 2014-10-02 CO CO14218631A patent/CO7160024A2/es unknown
-
2016
- 2016-09-21 US US15/272,348 patent/US20170009253A1/en not_active Abandoned
-
2017
- 2017-10-18 AU AU2017248469A patent/AU2017248469A1/en not_active Abandoned
-
2018
- 2018-08-07 CY CY20181100819T patent/CY1120531T1/el unknown
-
2023
- 2023-02-17 AR ARP230100383A patent/AR128556A2/es unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO7160024A2 (es) | Biocontrol | |
GT201700048A (es) | Terapias de combinación con anticuerpos anti-cd38 | |
CL2013002068A1 (es) | Linea celular de ratón con genes inactivados nav1.7 global viable; metodo para generar ratón con dichos genes inactivados; hibridoma. | |
MX2013008538A (es) | Amplificador compensado de fijacion de membrana para la secuenciacion de polinucleotido por nanoporo y otras aplicaciones. | |
CL2012002698A1 (es) | Artículo para fumar que comprende un sistema de flujo variable configurado para controlar de forma variable el flujo gaseoso en o a través del artículo para fumar. | |
CO6571889A2 (es) | Antidotos anticoagulantes | |
EP3022323A4 (en) | Specific nucleic acid amplification with compounded selectivity | |
BR112013016369A2 (pt) | sistema do tipo soldagem e método de calcular um custo de uma operação de soldagem, com calculador de custo | |
CY1117490T1 (el) | Μεθοδος παραγωγης της μεδετομιδινης | |
EP3109442A4 (en) | Fuel supply line system used for gas turbine | |
CL2011002403S1 (es) | Luminaria solar. | |
ITRM20120113A1 (it) | Complesso di governo per una nave con unità di propulsione disassate verticalmente. | |
UA113843C2 (xx) | Стійка до бактерій трансгенна рослина, яка містить дисфункціональні білки t3ss | |
HN2010001614A (es) | Confitura | |
BR112013026464A2 (pt) | sistema de transporte incluindo um veículo flutuante | |
CL2017001383A1 (es) | Proceso para la fabricación de anhídrido carboxílico | |
IT1402405B1 (it) | Dispositivo di alimentazione-separazione filo. | |
CL2012001192S1 (es) | Botella. | |
EP3247361A4 (en) | Pteridine dione monocarboxylate transporter inhibitors | |
IT1404534B1 (it) | Sistema di illuminazione. | |
IT1405068B1 (it) | Produzione di aldeidi per ossidazione in ambiente acquoso con recupero selettivo del prodotto mediante pervaporazione | |
CL2014000033A1 (es) | Fago geneticamente modificado con un sistema de expresion; genes s, r y/o q, lnt y/o xis son inactivados; y uso del mismo. | |
MX2015002908A (es) | Polipeptido con actividad reforzada de beta-glucosidasa a baja temperatura. | |
UA75890U (xx) | Повітряний транспортер | |
UA111656C2 (uk) | Спосіб одержання медетомідину з використанням хлорацетону |