MX2014010501A - Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act). - Google Patents

Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act).

Info

Publication number
MX2014010501A
MX2014010501A MX2014010501A MX2014010501A MX2014010501A MX 2014010501 A MX2014010501 A MX 2014010501A MX 2014010501 A MX2014010501 A MX 2014010501A MX 2014010501 A MX2014010501 A MX 2014010501A MX 2014010501 A MX2014010501 A MX 2014010501A
Authority
MX
Mexico
Prior art keywords
act
peptides
alpha connexin
terminal
gels containing
Prior art date
Application number
MX2014010501A
Other languages
English (en)
Other versions
MX351881B (es
Inventor
Gautam Ghatnekar
Original Assignee
Firststring Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firststring Res Inc filed Critical Firststring Res Inc
Publication of MX2014010501A publication Critical patent/MX2014010501A/es
Publication of MX351881B publication Critical patent/MX351881B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)

Abstract

Preparación de un fármaco en forma de gel tópico que contiene una composición que comprende un polipéptido aislado que tiene una secuencia de aminoácidos carboxilo terminal de una alfa-conexina (péptido ACT), estabilizantes de péptidos, excipientes, agentes amortiguadores del pH y semejantes. Se divulgan la formulación y los pasos de preparación para la elaboración de un gel tópico estable, elegante y vertible. La formulación resultante presenta una estabilidad a largo plazo adecuada para aplicaciones estéticas y terapéuticas, inclusive para prevenir la formación de cicatrices y para acelerar la curación de heridas.
MX2014010501A 2012-03-01 2013-03-01 Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act). MX351881B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261605528P 2012-03-01 2012-03-01
PCT/US2013/028727 WO2013131040A1 (en) 2012-03-01 2013-03-01 Topical gels containing alpha connexin c-terminal (act) peptides

Publications (2)

Publication Number Publication Date
MX2014010501A true MX2014010501A (es) 2015-03-09
MX351881B MX351881B (es) 2017-11-01

Family

ID=49083360

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014010501A MX351881B (es) 2012-03-01 2013-03-01 Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act).

Country Status (18)

Country Link
US (5) US8846605B2 (es)
EP (1) EP2819682B1 (es)
JP (1) JP6185937B2 (es)
KR (1) KR102038948B1 (es)
CN (1) CN104271142B (es)
AU (1) AU2013225716B2 (es)
BR (1) BR112014021653B1 (es)
CA (1) CA2866115C (es)
DK (1) DK2819682T3 (es)
HK (1) HK1205451A1 (es)
IL (1) IL234380B (es)
IN (1) IN2014DN07420A (es)
MX (1) MX351881B (es)
NZ (1) NZ629769A (es)
RU (1) RU2657535C2 (es)
SG (1) SG11201405359YA (es)
WO (1) WO2013131040A1 (es)
ZA (1) ZA201406373B (es)

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MX351881B (es) 2012-03-01 2017-11-01 Firststring Res Inc Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act).
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MX351881B (es) 2012-03-01 2017-11-01 Firststring Res Inc Geles tópicos que contienen péptidos de alfa-conexina c- terminal (act).

Also Published As

Publication number Publication date
NZ629769A (en) 2016-09-30
IL234380B (en) 2020-10-29
ZA201406373B (en) 2015-12-23
HK1205451A1 (en) 2015-12-18
MX351881B (es) 2017-11-01
US11524049B2 (en) 2022-12-13
RU2014139668A (ru) 2016-04-20
KR20140132388A (ko) 2014-11-17
JP6185937B2 (ja) 2017-08-23
AU2013225716A1 (en) 2014-09-18
AU2013225716B2 (en) 2017-10-12
CA2866115A1 (en) 2013-09-06
BR112014021653B1 (pt) 2023-03-28
EP2819682B1 (en) 2017-05-03
BR112014021653A2 (pt) 2022-05-10
EP2819682A1 (en) 2015-01-07
US10632173B2 (en) 2020-04-28
US20210128682A1 (en) 2021-05-06
US20150018284A1 (en) 2015-01-15
CN104271142A (zh) 2015-01-07
CA2866115C (en) 2020-03-24
US9161984B2 (en) 2015-10-20
CN104271142B (zh) 2017-07-04
SG11201405359YA (en) 2014-09-26
DK2819682T3 (en) 2017-08-21
IN2014DN07420A (es) 2015-04-24
JP2015513549A (ja) 2015-05-14
RU2657535C2 (ru) 2018-06-14
US20230263857A1 (en) 2023-08-24
US20160058834A1 (en) 2016-03-03
US8846605B2 (en) 2014-09-30
WO2013131040A1 (en) 2013-09-06
US20130267471A1 (en) 2013-10-10
KR102038948B1 (ko) 2019-11-26
EP2819682A4 (en) 2016-01-06

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